| Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations SA MacParland, JC Liu, XZ Ma, BT Innes, AM Bartczak, BK Gage, ... Nature communications 9 (1), 4383, 2018 | 1273 | 2018 |
| A clinically applicable integrative molecular classification of meningiomas F Nassiri, J Liu, V Patil, Y Mamatjan, JZ Wang, R Hugh-White, AM Macklin, ... Nature 597 (7874), 119-125, 2021 | 331 | 2021 |
| Identification of tumorsphere-and tumor-initiating cells in HER2/Neu-induced mammary tumors JC Liu, T Deng, RS Lehal, J Kim, E Zacksenhaus Cancer research 67 (18), 8671-8681, 2007 | 191 | 2007 |
| Single‐cell, single‐nucleus, and spatial RNA sequencing of the human liver identifies cholangiocyte and mesenchymal heterogeneity TS Andrews, J Atif, JC Liu, CT Perciani, XZ Ma, C Thoeni, M Slyper, ... Hepatology Communications 6 (4), 821-840, 2022 | 172 | 2022 |
| Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status Z Jiang, T Deng, R Jones, H Li, JI Herschkowitz, JC Liu, VJ Weigman, ... The Journal of clinical investigation 120 (9), 3296-3309, 2010 | 168 | 2010 |
| Cooperation between Pik3ca and p53 Mutations in Mouse Mammary Tumor Formation JR Adams, K Xu, JC Liu, NMR Agamez, AJ Loch, RG Wong, W Wang, ... Cancer research 71 (7), 2706-2717, 2011 | 166 | 2011 |
| RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation RA Jones, TJ Robinson, JC Liu, M Shrestha, V Voisin, YJ Ju, PED Chung, ... The Journal of clinical investigation 126 (10), 3739-3757, 2016 | 143 | 2016 |
| Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial F Nassiri, V Patil, LS Yefet, O Singh, J Liu, RMA Dang, TN Yamaguchi, ... Nature medicine 29 (6), 1370-1378, 2023 | 139 | 2023 |
| Mitochondrial OXPHOS induced by RB1 deficiency in breast cancer: implications for anabolic metabolism, stemness, and metastasis E Zacksenhaus, M Shrestha, JC Liu, I Vorobieva, PED Chung, YJ Ju, ... Trends in cancer 3 (11), 768-779, 2017 | 138 | 2017 |
| Combined deletion of P ten and p53 in mammary epithelium accelerates triple‐negative breast cancer with dependency on e EF 2 K JC Liu, V Voisin, S Wang, DY Wang, RA Jones, A Datti, D Uehling, ... EMBO molecular medicine 6 (12), 1542-1560, 2014 | 128 | 2014 |
| RB1 and p53 at the crossroad of EMT and triple-negative breast cancer Z Jiang, R Jones, JC Liu, T Deng, T Robinson, PED Chung, S Wang, ... Cell cycle 10 (10), 1563-1570, 2011 | 127 | 2011 |
| Seventeen-gene signature from enriched Her2/Neu mammary tumor-initiating cells predicts clinical outcome for human HER2+: ERα− breast cancer JC Liu, V Voisin, GD Bader, T Deng, L Pusztai, WF Symmans, FJ Esteva, ... Proceedings of the National Academy of Sciences 109 (15), 5832-5837, 2012 | 103 | 2012 |
| RB1 status in triple negative breast cancer cells dictates response to radiation treatment and selective therapeutic drugs TJW Robinson, JC Liu, F Vizeacoumar, T Sun, N Maclean, SE Egan, ... PloS one 8 (11), e78641, 2013 | 101 | 2013 |
| High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells: interaction with IQ motif-containing factors T Robinson, M Pai, J Liu, F Vizeacoumar, T Sun, S Egan, A Datti, J Huang, ... Cell Cycle 12 (18), 3013-3024, 2013 | 84 | 2013 |
| Generation of functional liver sinusoidal endothelial cells from human pluripotent stem-cell-derived venous angioblasts BK Gage, JC Liu, BT Innes, SA MacParland, ID McGilvray, GD Bader, ... Cell Stem Cell 27 (2), 254-269. e9, 2020 | 82 | 2020 |
| Activation of Go-coupled dopamine D2 receptors inhibits ERK1/ERK2 in pituitary cells: a key step in the transcriptional suppression of the prolactin gene JC Liu, RE Baker, C Sun, VC Sundmark, HP Elsholtz Journal of Biological Chemistry 277 (39), 35819-35825, 2002 | 82 | 2002 |
| Ras signaling is a key determinant for metastatic dissemination and poor survival of luminal breast cancer patients KL Wright, JR Adams, JC Liu, AJ Loch, RG Wong, CEB Jo, LA Beck, ... Cancer research 75 (22), 4960-4972, 2015 | 80 | 2015 |
| Identification of CDC25 as a common therapeutic target for triple-negative breast cancer JC Liu, L Granieri, M Shrestha, DY Wang, I Vorobieva, EA Rubie, R Jones, ... Cell reports 23 (1), 112-126, 2018 | 78 | 2018 |
| Elevated PI3K signaling drives multiple breast cancer subtypes JR Adams, NF Schachter, JC Liu, E Zacksenhaus, SE Egan Oncotarget 2 (6), 435, 2011 | 74 | 2011 |
| Ketoconazole and posaconazole selectively target HK2-expressing glioblastoma cells S Agnihotri, S Mansouri, K Burrell, M Li, Y Mamatjan, J Liu, R Nejad, ... Clinical Cancer Research 25 (2), 844-855, 2019 | 71 | 2019 |
Eldad ZacksenhausProfessor of Medicine, University of TorontoPatvirtintas el. paštas utoronto.ca