Immune checkpoints and their inhibition in cancer and infectious diseases L Dyck, KHG Mills European journal of immunology 47 (5), 765-779, 2017 | 597 | 2017 |
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses X Michelet, L Dyck, A Hogan, RM Loftus, D Duquette, K Wei, S Beyaz, ... Nature immunology 19 (12), 1330-1340, 2018 | 550 | 2018 |
Srebp-controlled glucose metabolism is essential for NK cell functional responses N Assmann, KL O'Brien, RP Donnelly, L Dyck, V Zaiatz-Bittencourt, ... Nature immunology 18 (11), 1197-1206, 2017 | 338 | 2017 |
Pyruvate kinase M2 is required for the expression of the immune checkpoint PD-L1 in immune cells and tumors EM Palsson-McDermott, L Dyck, Z Zasłona, D Menon, AF McGettrick, ... Frontiers in immunology 8, 1300, 2017 | 165 | 2017 |
Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments N Lopes, C McIntyre, S Martin, M Raverdeau, N Sumaria, AC Kohlgruber, ... Nature immunology 22 (2), 179-192, 2021 | 163 | 2021 |
Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN K Menck, C Scharf, A Bleckmann, L Dyck, U Rost, D Wenzel, VM Dhople, ... Journal of molecular cell biology 7 (2), 143-153, 2015 | 159 | 2015 |
Suppressive effects of the obese tumor microenvironment on CD8 T cell infiltration and effector function L Dyck, H Prendeville, M Raverdeau, MM Wilk, RM Loftus, A Douglas, ... Journal of Experimental Medicine 219 (3), e20210042, 2022 | 89 | 2022 |
Anti-PD-1 inhibits Foxp3+ Treg cell conversion and unleashes intratumoural effector T cells thereby enhancing the efficacy of a cancer vaccine in a mouse model L Dyck, MM Wilk, M Raverdeau, A Misiak, L Boon, KHG Mills Cancer Immunology, Immunotherapy 65, 1491-1498, 2016 | 74 | 2016 |
Blocking retinoic acid receptor-α enhances the efficacy of a dendritic cell vaccine against tumours by suppressing the induction of regulatory T cells KC Galvin, L Dyck, NA Marshall, AM Stefanska, KP Walsh, B Moran, ... Cancer immunology, immunotherapy 62, 1273-1282, 2013 | 64 | 2013 |
Modulation of apoptosis sensitivity through the interplay with autophagic and proteasomal degradation pathways ME Delgado, L Dyck, MA Laussmann, M Rehm Cell death & disease 5 (1), e1011-e1011, 2014 | 57 | 2014 |
Cancer, obesity and immunometabolism–Connecting the dots L Dyck, L Lynch Cancer Letters 417, 11-20, 2018 | 47 | 2018 |
New job for NK cells: architects of the tumor microenvironment L Dyck, L Lynch Immunity 48 (1), 9-11, 2018 | 22 | 2018 |
Proteasome inhibition triggers the formation of TRAIL receptor 2 platforms for caspase-8 activation that accumulate in the cytosol CT Hellwig, ME Delgado, J Skoko, L Dyck, C Hanna, A Wentges, ... Cell Death & Differentiation 29 (1), 147-155, 2022 | 13 | 2022 |
Diverse effects of obesity on antitumor immunity and immunotherapy L Dyck, L Lynch Trends in Molecular Medicine 29 (2), 112-123, 2023 | 11 | 2023 |
Modulation of apoptosis sensitivity through the interplay with autophagic and proteasomal degradation pathways. Cell Death Dis 2014; 5: e1011; PMID: 24457955 ME Delgado, L Dyck, MA Laussmann, M Rehm | 5 | 2013 |
Region-specific phosphorylation determines neuroligin-3 localization to excitatory versus inhibitory synapses B Altas, LP Tuffy, A Patrizi, K Dimova, T Soykan, C Brandenburg, ... Biological Psychiatry 96 (10), 815-828, 2024 | 1 | 2024 |
Phosphorylation Determines Whether Neuroligin-3 is at Excitatory or Inhibitory Synapses in Different Regions of the Brain B Altas, LP Tuffy, A Patrizi, K Dimova, T Soykan, AJ Romanowski, ... bioRxiv, 2022.07. 23.501257, 2022 | 1 | 2022 |
38/# 924 Immunometabolic changes during weight loss induce tumor immunogenicity resulting in tumor regression M Brennan, L Dyck, H Prendeville, D Brennan, L Lynch International Journal of Gynecological Cancer 32 (Suppl 3), A42-A42, 2022 | | 2022 |
O66: FLOW CYTOMETRIC AND RNA SEQUENCED UNCOUPLING OF TUMOUR-INFILTRATING LYMPHOCYTE CHECKPOINT EXPRESSION AND MISMATCH REPAIR STATUS IN COLORECTAL CANCER A Zaborowski, C Harmon, D Duquette, L Dyck, L Lynch, D Winter British Journal of Surgery 108 (Supplement_1), znab117. 066, 2021 | | 2021 |
BLOCKING PD-1 IMPROVES THE EFFICACY OF A CANCER VACCINE BY REDUCING TUMOUR-INFILTRATING TREG CELLS AND ENHANCING EFFECTOR T CELL RESPONSES IN A MURINE TUMOUR MODEL L Dyck, MM Wilk, M Raverdeau, A Misiak, KHG Mills CYTOKINE 87, 111-111, 2016 | | 2016 |