Microglia-mediated neurotoxicity: uncovering the molecular mechanisms ML Block, L Zecca, JS Hong Nature Reviews Neuroscience 8 (1), 57-69, 2007 | 4800 | 2007 |
Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration L Qin, X Wu, ML Block, Y Liu, GR Breese, JS Hong, DJ Knapp, FT Crews Glia 55 (5), 453-462, 2007 | 2505 | 2007 |
Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism ML Block, JS Hong Progress in neurobiology 76 (2), 77-98, 2005 | 1934 | 2005 |
Air pollution: mechanisms of neuroinflammation and CNS disease ML Block, L Calderón-Garcidueñas Trends in neurosciences 32 (9), 506-516, 2009 | 1679 | 2009 |
Aggregated α‐synuclein activates microglia: a process leading to disease progression in Parkinson's disease W Zhang, T Wang, Z Pei, DS Miller, X Wu, ML Block, B Wilson, W Zhang, ... The FASEB Journal 19 (6), 533-542, 2005 | 1485 | 2005 |
Microglial activation and chronic neurodegeneration ME Lull, ML Block Neurotherapeutics 7 (4), 354-365, 2010 | 1172 | 2010 |
NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia L Qin, Y Liu, T Wang, SJ Wei, ML Block, B Wilson, B Liu, JS Hong Journal of Biological Chemistry 279 (2), 1415-1421, 2004 | 698 | 2004 |
The outdoor air pollution and brain health workshop ML Block, A Elder, RL Auten, SD Bilbo, H Chen, JC Chen, ... Neurotoxicology 33 (5), 972-984, 2012 | 598 | 2012 |
Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase ML Block, X Wu, Z Pei, G Li, T Wang, L Qin, B Wilson, J Yang, JS Hong, ... The FASEB journal 18 (13), 1618-1620, 2004 | 449 | 2004 |
Chronic microglial activation and progressive dopaminergic neurotoxicity ML Block, JS Hong Biochemical Society Transactions 35 (5), 1127-1132, 2007 | 432 | 2007 |
Diesel exhaust activates and primes microglia: air pollution, neuroinflammation, and regulation of dopaminergic neurotoxicity S Levesque, T Taetzsch, ME Lull, U Kodavanti, K Stadler, A Wagner, ... Environmental health perspectives 119 (8), 1149-1155, 2011 | 413 | 2011 |
Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease S Levesque, MJ Surace, J McDonald, ML Block Journal of neuroinflammation 8, 1-10, 2011 | 388 | 2011 |
Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons X Wu, PS Chen, S Dallas, B Wilson, ML Block, CC Wang, H Kinyamu, ... International Journal of Neuropsychopharmacology 11 (8), 1123-1134, 2008 | 361 | 2008 |
Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults L Calderón-Garcidueñas, M Kavanaugh, M Block, A D'Angiulli, ... Journal of Alzheimer’s Disease 28 (1), 93-107, 2012 | 315 | 2012 |
Retinoic acid attenuates β-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model Y Ding, A Qiao, Z Wang, JS Goodwin, ES Lee, ML Block, M Allsbrook, ... Journal of Neuroscience 28 (45), 11622-11634, 2008 | 310 | 2008 |
Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier AMS Hartz, B Bauer, ML Block, JS Hong, DS Miller The FASEB Journal 22 (8), 2723, 2008 | 301 | 2008 |
Interactive role of the toll‐like receptor 4 and reactive oxygen species in LPS‐induced microglia activation L Qin, G Li, X Qian, Y Liu, X Wu, B Liu, JS Hong, ML Block Glia 52 (1), 78-84, 2005 | 255 | 2005 |
Particulate matter, oxidative stress and neurotoxicity SMJ MohanKumar, A Campbell, M Block, B Veronesi Neurotoxicology 29 (3), 479-488, 2008 | 251 | 2008 |
A pivotal role of matrix metalloproteinase‐3 activity in dopaminergic neuronal degeneration via microglial activation YS Kim, DH Choi, ML Block, S Lorenzl, L Yang, YJ Kim, S Sugama, ... The FASEB Journal 21 (1), 179-187, 2007 | 248 | 2007 |
NADPH oxidase as a therapeutic target in Alzheimer's disease ML Block BMC neuroscience 9 (Suppl 2), S8, 2008 | 230 | 2008 |