Downregulation of Kv7. 4 channel activity in primary and secondary hypertension TA Jepps, PS Chadha, AJ Davis, MI Harhun, GW Cockerill, SP Olesen, ... Circulation 124 (5), 602-611, 2011 | 187 | 2011 |
Expression and function of the K+ channel KCNQ genes in human arteries FL Ng, AJ Davis, TA Jepps, MI Harhun, SY Yeung, A Wan, M Reddy, ... British journal of pharmacology 162 (1), 42-53, 2011 | 157 | 2011 |
Expression profile and protein translation of TMEM16A in murine smooth muscle AJ Davis, AS Forrest, TA Jepps, ML Valencik, M Wiwchar, CA Singer, ... American Journal of Physiology-Cell Physiology 299 (5), C948-C959, 2010 | 148 | 2010 |
Reduced KCNQ4-encoded voltage-dependent potassium channel activity underlies impaired β-adrenoceptor–mediated relaxation of renal arteries in hypertension PS Chadha, F Zunke, HL Zhu, AJ Davis, TA Jepps, SP Olesen, WC Cole, ... Hypertension 59 (4), 877-884, 2012 | 132 | 2012 |
KV7 potassium channels: a new therapeutic target in smooth muscle disorders JB Stott, TA Jepps, IA Greenwood Drug discovery today 19 (4), 413-424, 2014 | 122 | 2014 |
Contribution of Kv7. 4/Kv7. 5 heteromers to intrinsic and calcitonin gene-related peptide–induced cerebral reactivity PS Chadha, TA Jepps, G Carr, JB Stott, HL Zhu, WC Cole, IA Greenwood Arteriosclerosis, thrombosis, and vascular biology 34 (4), 887-893, 2014 | 107 | 2014 |
Contribution of Kv7 Channels to Basal Coronary Flow and Active Response to Ischemia S Khanamiri, E Soltysinska, TA Jepps, BH Bentzen, PS Chadha, ... Hypertension 62 (6), 1090-1097, 2013 | 95 | 2013 |
Molecular and functional characterization of Kv7 K+ channel in murine gastrointestinal smooth muscles TA Jepps, IA Greenwood, JD Moffatt, KM Sanders, S Ohya American Journal of Physiology-Gastrointestinal and Liver Physiology 297 (1 …, 2009 | 85 | 2009 |
Fundamental role for the KCNE4 ancillary subunit in Kv7. 4 regulation of arterial tone TA Jepps, G Carr, PR Lundegaard, SP Olesen, IA Greenwood The Journal of physiology 593 (24), 5325-5340, 2015 | 80 | 2015 |
Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats JB Stott, V Barrese, TA Jepps, EV Leighton, IA Greenwood Hypertension 65 (3), 676-682, 2015 | 69 | 2015 |
Pharmacological dissection of Kv7.1 channels in systemic and pulmonary arteries PS Chadha, F Zunke, AJ Davis, TA Jepps, JTM Linders, M Schwake, ... British journal of pharmacology 166 (4), 1377-1387, 2012 | 68 | 2012 |
One man's side effect is another man's therapeutic opportunity: targeting Kv7 channels in smooth muscle disorders TA Jepps, SP Olesen, IA Greenwood British journal of pharmacology 168 (1), 19-27, 2013 | 63 | 2013 |
MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension G Carr, V Barrese, JB Stott, OV Povstyan, TA Jepps, HB Figueiredo, ... Cardiovascular research 112 (2), 581-589, 2016 | 57 | 2016 |
KCNQ5 activation is a unifying molecular mechanism shared by genetically and culturally diverse botanical hypotensive folk medicines RW Manville, J Van Der Horst, KE Redford, BB Katz, TA Jepps, GW Abbott Proceedings of the National Academy of Sciences 116 (42), 21236-21245, 2019 | 53 | 2019 |
Vasorelaxant effects of novel Kv7.4 channel enhancers ML213 and NS15370 TA Jepps, BH Bentzen, JB Stott, OV Povstyan, K Sivaloganathan, ... British Journal of Pharmacology 171 (19), 4413-4424, 2014 | 46 | 2014 |
Cyclic AMP-dependent regulation of Kv7 voltage-gated potassium channels J Van der Horst, IA Greenwood, TA Jepps Frontiers in physiology 11, 727, 2020 | 45 | 2020 |
Kcne4 deletion sex-dependently alters vascular reactivity GW Abbott, TA Jepps Journal of vascular research 53 (3-4), 138-148, 2016 | 44 | 2016 |
TMEM16A is implicated in the regulation of coronary flow and is altered in hypertension HR Askew Page, T Dalsgaard, SN Baldwin, TA Jepps, O Povstyan, ... British Journal of Pharmacology 176 (11), 1635-1648, 2019 | 41 | 2019 |
4‐aminopyridine: a pan Kv channel inhibitor that enhances Kv7. 4 currents and inhibits noradrenaline‐mediated contraction of rat mesenteric small arteries MM Khammy, S Kim, BH Bentzen, S Lee, I Choi, C Aalkjær, TA Jepps British Journal of Pharmacology, 2017 | 33* | 2017 |
Molecular and functional characterization of Kv7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats TA Jepps, SP Olesen, IA Greenwood, T Dalsgaard British journal of pharmacology 173 (9), 1478-1490, 2016 | 32 | 2016 |