| Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson’s disease S Sarkar, E Malovic, DS Harishchandra, S Ghaisas, N Panicker, A Charli, ... npj Parkinson's Disease 3 (1), 30, 2017 | 252 | 2017 |
| Manganese-induced neurotoxicity: new insights into the triad of protein misfolding, mitochondrial impairment, and neuroinflammation DS Harischandra, S Ghaisas, G Zenitsky, H Jin, A Kanthasamy, ... Frontiers in neuroscience 13, 654, 2019 | 244 | 2019 |
| Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia N Panicker, S Sarkar, DS Harischandra, M Neal, TI Kam, H Jin, ... Journal of Experimental Medicine 216 (6), 1411-1430, 2019 | 236 | 2019 |
| Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein DS Harischandra, D Rokad, ML Neal, S Ghaisas, S Manne, S Sarkar, ... Science signaling 12 (572), eaau4543, 2019 | 168 | 2019 |
| Fyn kinase regulates microglial neuroinflammatory responses in cell culture and animal models of Parkinson's disease N Panicker, H Saminathan, H Jin, M Neal, DS Harischandra, R Gordon, ... Journal of Neuroscience 35 (27), 10058-10077, 2015 | 166 | 2015 |
| Manganese exposure induces neuroinflammation by impairing mitochondrial dynamics in astrocytes S Sarkar, E Malovic, DS Harischandra, HA Ngwa, A Ghosh, C Hogan, ... Neurotoxicology 64, 204-218, 2018 | 146 | 2018 |
| Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells S Sarkar, D Rokad, E Malovic, J Luo, DS Harischandra, H Jin, ... Science Signaling 12 (563), eaat9900, 2019 | 138 | 2019 |
| Prokineticin‐2 promotes chemotaxis and alternative A2 reactivity of astrocytes M Neal, J Luo, DS Harischandra, R Gordon, S Sarkar, H Jin, ... Glia 66 (10), 2137-2157, 2018 | 131 | 2018 |
| Kv1. 3 modulates neuroinflammation and neurodegeneration in Parkinson’s disease S Sarkar, HM Nguyen, E Malovic, J Luo, M Langley, BN Palanisamy, ... The Journal of clinical investigation 130 (8), 4195-4212, 2020 | 124 | 2020 |
| Mitoapocynin treatment protects against neuroinflammation and dopaminergic neurodegeneration in a preclinical animal model of Parkinson’s disease A Ghosh, MR Langley, DS Harischandra, ML Neal, H Jin, V Anantharam, ... Journal of Neuroimmune Pharmacology 11, 259-278, 2016 | 109 | 2016 |
| α-Synuclein protects against manganese neurotoxic insult during the early stages of exposure in a dopaminergic cell model of Parkinson’s disease DS Harischandra, H Jin, V Anantharam, A Kanthasamy, AG Kanthasamy Toxicological Sciences 143 (2), 454-468, 2015 | 106 | 2015 |
| Environmental neurotoxicant manganese regulates exosome-mediated extracellular miRNAs in cell culture model of Parkinson's disease: Relevance to α-synuclein misfolding in metal … DS Harischandra, S Ghaisas, D Rokad, M Zamanian, H Jin, ... Neurotoxicology 64, 267-277, 2018 | 104 | 2018 |
| Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease R Gordon, N Singh, V Lawana, A Ghosh, DS Harischandra, H Jin, ... Neurobiology of disease 93, 96-114, 2016 | 104 | 2016 |
| Neuronal protection against oxidative insult by polyanhydride nanoparticle-based mitochondria-targeted antioxidant therapy TM Brenza, S Ghaisas, JEV Ramirez, D Harischandra, V Anantharam, ... Nanomedicine: Nanotechnology, biology and medicine 13 (3), 809-820, 2017 | 99 | 2017 |
| Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degeneration R Gordon, ML Neal, J Luo, MR Langley, DS Harischandra, N Panicker, ... Nature communications 7 (1), 12932, 2016 | 98 | 2016 |
| The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease A Ghosh, H Saminathan, A Kanthasamy, V Anantharam, H Jin, ... Journal of Biological Chemistry 288 (30), 21955-21971, 2013 | 98 | 2013 |
| Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease H Jin, A Kanthasamy, DS Harischandra, N Kondru, A Ghosh, N Panicker, ... Journal of Biological Chemistry 289 (50), 34743-34767, 2014 | 90 | 2014 |
| Role of neurotoxicants and traumatic brain injury in α-synuclein protein misfolding and aggregation D Rokad, S Ghaisas, DS Harischandra, H Jin, V Anantharam, ... Brain research bulletin 133, 60-70, 2017 | 68 | 2017 |
| Exosomes in toxicology: relevance to chemical exposure and pathogenesis of environmentally linked diseases DS Harischandra, S Ghaisas, D Rokad, AG Kanthasamy Toxicological Sciences 158 (1), 3-13, 2017 | 56 | 2017 |
| TRIM11 protects against tauopathies and is down-regulated in Alzheimer’s disease ZY Zhang, DS Harischandra, R Wang, S Ghaisas, JY Zhao, ... Science 381 (6656), eadd6696, 2023 | 53 | 2023 |
Vellareddy AnantharamAssociate Professor of Biomedical Sciences, Iowa State UniversityPatvirtintas el. paštas iastate.edu