| Catalytic dyad residues His41 and Cys145 impact the catalytic activity and overall conformational fold of the main SARS-CoV-2 protease 3-chymotrypsin-like protease JC Ferreira, S Fadl, AJ Villanueva, WM Rabeh Frontiers in Chemistry 9, 692168, 2021 | 112 | 2021 |
| The catalytic inactivation of the N-half of human hexokinase 2 and structural and biochemical characterization of its mitochondrial conformation MH Nawaz, JC Ferreira, L Nedyalkova, H Zhu, C Carrasco-López, ... Bioscience reports 38 (1), 2018 | 73 | 2018 |
| Biochemical and biophysical characterization of the main protease, 3-chymotrypsin-like protease (3CLpro) from the novel coronavirus SARS-CoV 2 JC Ferreira, WM Rabeh Scientific reports 10 (1), 22200, 2020 | 46 | 2020 |
| Key dimer interface residues impact the catalytic activity of 3CLpro, the main protease of SARS-CoV-2 JC Ferreira, S Fadl, WM Rabeh Journal of Biological Chemistry 298 (6), 2022 | 44 | 2022 |
| On the mechanisms of phenothiazine-induced mitochondrial permeability transition: Thiol oxidation, strict Ca< sup> 2+</sup> dependence, and cyt< i> c</i> release TS Cruz, PA Faria, DP Santana, JC Ferreira, V Oliveira, OR Nascimento, ... Biochemical pharmacology 80 (8), 1284-1295, 2010 | 44 | 2010 |
| Oligomerization of the cysteinyl-rich oligopeptidase EP24. 15 is triggered by S-glutathionylation M Demasi, GM Piassa Filho, LM Castro, JC Ferreira, V Rioli, ES Ferro Free Radical Biology and Medicine 44 (6), 1180-1190, 2008 | 40 | 2008 |
| Not Only Oxidation of Cardiolipin Affects the Affinity of Cytochrome c for Lipid Bilayers C Kawai, JC Ferreira, MS Baptista, IL Nantes The Journal of Physical Chemistry B 118 (41), 11863-11872, 2014 | 32 | 2014 |
| Beetle luciferases with naturally red-and blue-shifted emission C Carrasco-López, JC Ferreira, NM Lui, S Schramm, R Berraud-Pache, ... Life science alliance 1 (4), 2018 | 30 | 2018 |
| Dimethyl sulfoxide reduces the stability but enhances catalytic activity of the main SARS‐CoV‐2 protease 3CLpro JC Ferreira, S Fadl, M Ilter, H Pekel, R Rezgui, O Sensoy, WM Rabeh The FASEB Journal 35 (8), 2021 | 19 | 2021 |
| pH profiles of 3-chymotrypsin-like protease (3CLpro) from SARS-CoV-2 elucidate its catalytic mechanism and a histidine residue critical for activity K Al Adem, JC Ferreira, S Fadl, WM Rabeh Journal of Biological Chemistry, 102790, 2022 | 15 | 2022 |
| Linker residues regulate the activity and stability of hexokinase 2, a promising anticancer target JC Ferreira, AR Khrbtli, CL Shetler, S Mansoor, L Ali, O Sensoy, ... Journal of Biological Chemistry 296, 2021 | 15 | 2021 |
| Key allosteric and active site residues of SARS-CoV-2 3CLpro are promising drug targets K Al Adem, JC Ferreira, S Fadl, M Mustafa, WM Rabeh Biochemical Journal 480 (11), 791-813, 2023 | 12 | 2023 |
| Redox modulation of thimet oligopeptidase activity by hydrogen peroxide MY Icimoto, JC Ferreira, CH Yokomizo, LV Bim, A Marem, JM Gilio, ... FEBS Open Bio 7 (7), 1037-1050, 2017 | 12 | 2017 |
| Intermediate tyrosyl radical and amyloid structure in peroxide-activated cytoglobin JC Ferreira, MF Marcondes, MY Icimoto, THS Cardoso, A Tofanello, ... PLoS One 10 (8), e0136554, 2015 | 12 | 2015 |
| Substrate specificity, physicochemical and kinetic properties of a trypsin from the giant Amazonian fish pirarucu (Arapaima gigas) ACV de Freitas-Júnior, HMS da Costa, M Marcuschi, MY Icimoto, ... Biocatalysis and Agricultural Biotechnology 35, 102073, 2021 | 11 | 2021 |
| Hysteretic behavior of proprotein convertase 1/3 (PC1/3) MY Icimoto, NM Barros, JC Ferreira, MF Marcondes, D Andrade, ... PloS one 6 (9), e24545, 2011 | 10 | 2011 |
| Therapeutic potential of metal ions for COVID-19: insights from the papain-like protease of SARS-CoV-2 CL Shetler, JC Ferreira, THS Cardoso, EMA Silva, NK Saksena, ... Biochemical Journal 479 (20), 2175-2193, 2022 | 9 | 2022 |
| The Discovery of Small Allosteric and Active Site Inhibitors of the SARS-CoV-2 Main Protease via Structure-Based Virtual Screening and Biological Evaluation RE Mahgoub, FE Mohamed, L Alzyoud, BR Ali, J Ferreira, WM Rabeh, ... Molecules 27 (19), 6710, 2022 | 7 | 2022 |
| SARS-CoV-2 variants, its recombinants and epigenomic exploitation of host defenses NK Saksena, SB Reddy, M Miranda-Saksena, THS Cardoso, EMA Silva, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 166836, 2023 | 6 | 2023 |
| Recycling of the High Valence States of Heme Proteins by Cysteine Residues of Thimet-Oligopeptidase JC Ferreira, MY Icimoto, MF Marcondes, V Oliveira, OR Nascimento, ... PloS one 8 (11), e79102, 2013 | 5 | 2013 |
