Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2 Y Liu, G Hu, Y Wang, W Ren, X Zhao, F Ji, Y Zhu, F Feng, M Gong, X Ju, ... Proceedings of the National Academy of Sciences 118 (12), e2025373118, 2021 | 262 | 2021 |
Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species R Wang, Q Zhang, J Ge, W Ren, R Zhang, J Lan, B Ju, B Su, F Yu, P Chen, ... Immunity 54 (7), 1611-1621. e5, 2021 | 243 | 2021 |
A novel cell culture system modeling the SARS-CoV-2 life cycle X Ju, Y Zhu, Y Wang, J Li, J Zhang, M Gong, W Ren, S Li, J Zhong, ... PLoS pathogens 17 (3), e1009439, 2021 | 160 | 2021 |
Phase separation of RNA-binding protein promotes polymerase binding and transcription W Shao, X Bi, Y Pan, B Gao, J Wu, Y Yin, Z Liu, M Peng, W Zhang, ... Nature Chemical Biology 18 (1), 70-80, 2022 | 100 | 2022 |
Mutation Y453F in the spike protein of SARS-CoV-2 enhances interaction with the mink ACE2 receptor for host adaption W Ren, J Lan, X Ju, M Gong, Q Long, Z Zhu, Y Yu, J Wu, J Zhong, ... PLoS pathogens 17 (11), e1010053, 2021 | 67 | 2021 |
Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2 S Zhang, Q Liang, X He, C Zhao, W Ren, Z Yang, Z Wang, Q Ding, ... Cell research 32 (3), 315-318, 2022 | 40 | 2022 |
Susceptibilities of human ACE2 genetic variants in coronavirus infection W Ren, Y Zhu, J Lan, H Chen, Y Wang, H Shi, F Feng, DY Chen, B Close, ... Journal of virology 96 (1), e01492-21, 2022 | 35 | 2022 |
Comparative analysis reveals the species-specific genetic determinants of ACE2 required for SARS-CoV-2 entry W Ren, Y Zhu, Y Wang, H Shi, Y Yu, G Hu, F Feng, X Zhao, J Lan, J Wu, ... PLoS pathogens 17 (3), e1009392, 2021 | 34 | 2021 |
Structural insights into the binding of SARS-CoV-2, SARS-CoV, and hCoV-NL63 spike receptor-binding domain to horse ACE2 J Lan, P Chen, W Liu, W Ren, L Zhang, Q Ding, Q Zhang, X Wang, J Ge Structure 30 (10), 1432-1442. e4, 2022 | 26 | 2022 |
Characterization of SARS-CoV-2 variants B. 1.617. 1 (Kappa), B. 1.617. 2 (Delta), and B. 1.618 by cell entry and immune evasion W Ren, X Ju, M Gong, J Lan, Y Yu, Q Long, DJ Kenney, AK O’Connell, ... Mbio 13 (2), e00099-22, 2022 | 24 | 2022 |
Evolution of immune evasion and host range expansion by the SARS-CoV-2 B. 1.1. 529 (Omicron) variant W Ren, Y Zhang, J Rao, Z Wang, J Lan, K Liu, X Zhang, X Hu, C Yang, ... Mbio 14 (2), e00416-23, 2023 | 15 | 2023 |
SARS-CoV-2 main protease cleaves MAGED2 to antagonize host antiviral defense X Ju, Z Wang, P Wang, W Ren, Y Yu, Y Yu, B Yuan, J Song, X Zhang, ... MBio 14 (4), e01373-23, 2023 | 9 | 2023 |
The PRMT5/WDR77 complex restricts hepatitis E virus replication X Ju, Y Yu, W Ren, L Dong, X Meng, H Deng, Y Nan, Q Ding PLoS Pathogens 19 (6), e1011434, 2023 | 6 | 2023 |
Zika virus NS5 protein inhibits type I interferon signaling via CRL3 E3 ubiquitin ligase-mediated degradation of STAT2 W Ren, C Fu, Y Zhang, X Ju, X Jiang, J Song, M Gong, Z Li, W Fan, J Yao, ... Proceedings of the National Academy of Sciences 121 (34), e2403235121, 2024 | 3 | 2024 |