| Engineering macrophage-derived exosomes for targeted paclitaxel delivery to pulmonary metastases: in vitro and in vivo evaluations MS Kim, MJ Haney, Y Zhao, D Yuan, I Deygen, NL Klyachko, AV Kabanov, ... Nanomedicine: Nanotechnology, Biology and Medicine 14 (1), 195-204, 2018 | 638 | 2018 |
| Macrophage exosomes as natural nanocarriers for protein delivery to inflamed brain D Yuan, Y Zhao, WA Banks, KM Bullock, M Haney, E Batrakova, ... Biomaterials 142, 1-12, 2017 | 554 | 2017 |
| Physiologically based pharmacokinetic modeling of nanoparticles D Yuan, H He, Y Wu, J Fan, Y Cao Journal of pharmaceutical sciences 108 (1), 58-72, 2019 | 156 | 2019 |
| Pharmacokinetics and pharmacodynamics modeling and simulation systems to support the development and regulation of liposomal drugs H He, D Yuan, Y Wu, Y Cao Pharmaceutics 11 (3), 110, 2019 | 79 | 2019 |
| Effect of octreotide–polyethylene glycol (100) monostearate modification on the pharmacokinetics and cellular uptake of nanostructured lipid carrier loaded with … Z Su, J Niu, Y Xiao, Q Ping, M Sun, A Huang, W You, X Sang, D Yuan Molecular pharmaceutics 8 (5), 1641-1651, 2011 | 71 | 2011 |
| A novel lipoprotein-mimic nanocarrier composed of the modified protein and lipid for tumor cell targeting delivery Y Xu, X Jin, Q Ping, J Cheng, M Sun, F Cao, W You, D Yuan Journal of controlled release 146 (3), 299-308, 2010 | 57 | 2010 |
| Pluronic modified leptin with increased systemic circulation, brain uptake and efficacy for treatment of obesity X Yi, D Yuan, SA Farr, WA Banks, CD Poon, AV Kabanov Journal of Controlled Release 191, 34-46, 2014 | 51 | 2014 |
| Intranasal delivery of N-terminal modified leptin-pluronic conjugate for treatment of obesity D Yuan, X Yi, Y Zhao, CD Poon, KM Bullock, KM Hansen, TS Salameh, ... Journal of Controlled Release 263, 172-184, 2017 | 32 | 2017 |
| Effect of ligand density and PEG modification on octreotide-targeted liposome via somatostatin receptor in vitro and in vivo H Li, D Yuan, M Sun, Q Ping Drug Delivery 23 (9), 3562-3572, 2016 | 23 | 2016 |
| Luteinizing hormone releasing hormone-targeted cisplatin-loaded magnetite nanoclusters for simultaneous MR imaging and chemotherapy of ovarian cancer HM Vishwasrao, AM Master, YG Seo, XM Liu, N Pothayee, Z Zhou, ... Chemistry of Materials 28 (9), 3024-3040, 2016 | 21 | 2016 |
| A minimal physiologically based pharmacokinetic model with a nested endosome compartment for novel engineered antibodies D Yuan, F Rode, Y Cao The AAPS journal 20, 1-11, 2018 | 18 | 2018 |
| Downregulation of Interferon-γ Receptor Expression Endows Resistance to Anti–Programmed Death Protein 1 Therapy in Colorectal Cancer C Lv, D Yuan, Y Cao The Journal of pharmacology and experimental therapeutics 376 (1), 21-28, 2021 | 9 | 2021 |
| Efficacy, safety, pharmacokinetic (PK), and pharmacodynamic (PD) support for talquetamab (tal) QW and Q2W dosing in patients (pts) with relapsed/refractory multiple myeloma … X Ma, J Gong, J Zhou, D Yuan, D Vishwamitra, B Hilder, TJ Masterson, ... Journal of Clinical Oncology 41 (16_suppl), 8041-8041, 2023 | 5 | 2023 |
| A systems pharmacokinetic/pharmacodynamic model for concizumab to explore the potential of anti-TFPI recycling antibodies D Yuan, F Rode, Y Cao European Journal of Pharmaceutical Sciences 138, 105032, 2019 | 4 | 2019 |
| 奥曲肽靶向阿霉素脂质体的制备及其体外性质 袁东芬， 孙敏捷， 王宇， 平其能 中国药科大学学报 42 (003), 223-229, 2011 | 4 | 2011 |
| Biological agent-exosome compositions and uses thereof EV Batrakova, AV Kabanov, M Sokolsky, MJ Haney, D Yuan, MS Kim US Patent 11,458,097, 2022 | 1 | 2022 |
| Biological agent-exosome compositions and uses thereof EV Batrakova, AV Kabanov, M Sokolsky, MJ Haney, D Yuan, MS Kim US Patent App. 17/821,576, 2022 | | 2022 |
| A Mechanistic Small Systems Model to Explore the Pharmacokinetics and Pharmacodynamics of Concizumab D Yuan, F Rode, Y Cao JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 45, S23-S23, 2018 | | 2018 |
| Delivery of Therapeutic Proteins to the Brain D Yuan The University of North Carolina at Chapel Hill, 2017 | | 2017 |
Alexander KabanovProfessor, University of North Carolina Chapel HillPatvirtintas el. paštas email.unc.edu