Stebėti
Rachel Kember
Rachel Kember
Assistant Professor, University of Pennsylvania
Patvirtintas el. paštas pennmedicine.upenn.edu
Pavadinimas
Cituota
Cituota
Metai
The power of genetic diversity in genome-wide association studies of lipids
SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ...
Nature 600 (7890), 675-679, 2021
6542021
A saturated map of common genetic variants associated with human height
L Yengo, S Vedantam, E Marouli, J Sidorenko, E Bartell, S Sakaue, ...
Nature 610 (7933), 704-712, 2022
5602022
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations
HR Kranzler, H Zhou, RL Kember, R Vickers Smith, AC Justice, ...
Nature communications 10 (1), 1499, 2019
5012019
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits
H Zhou, JM Sealock, S Sanchez-Roige, TK Clarke, DF Levey, Z Cheng, ...
Nature neuroscience 23 (7), 809-818, 2020
3292020
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
R Karlsson Linnér, TT Mallard, PB Barr, S Sanchez-Roige, JW Madole, ...
Nature neuroscience 24 (10), 1367-1376, 2021
2582021
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations
C Tcheandjieu, X Zhu, AT Hilliard, SL Clarke, V Napolioni, S Ma, KM Lee, ...
Nature medicine 28 (8), 1679-1692, 2022
2262022
Rare variants in the genetic background modulate cognitive and developmental phenotypes in individuals carrying disease-associated variants
L Pizzo, M Jensen, A Polyak, JA Rosenfeld, K Mannik, A Krishnan, ...
Genetics in Medicine 21 (4), 816-825, 2019
1822019
Maternal separation is associated with strain‐specific responses to stress and epigenetic alterations to Nr3c1, Avp, and Nr4a1 in mouse
RL Kember, EL Dempster, THA Lee, LC Schalkwyk, J Mill, C Fernandes
Brain and behavior 2 (4), 455-467, 2012
1732012
Association of OPRM1 functional coding variant with opioid use disorder: a genome-wide association study
H Zhou, CT Rentsch, Z Cheng, RL Kember, YZ Nunez, RM Sherva, ...
JAMA psychiatry 77 (10), 1072-1080, 2020
1542020
Genomics-first evaluation of heart disease associated with titin-truncating variants
CM Haggerty, SM Damrauer, MG Levin, D Birtwell, DJ Carey, AM Golden, ...
Circulation 140 (1), 42-54, 2019
1492019
Transcriptomic signatures across human tissues identify functional rare genetic variation
NM Ferraro, BJ Strober, J Einson, NS Abell, F Aguet, AN Barbeira, ...
Science 369 (6509), eaaz5900, 2020
1482020
Association of the V122I hereditary transthyretin amyloidosis genetic variant with heart failure among individuals of African or Hispanic/Latino ancestry
SM Damrauer, K Chaudhary, JH Cho, LW Liang, E Argulian, L Chan, ...
Jama 322 (22), 2191-2202, 2019
1322019
A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation
M Vujkovic, S Ramdas, KM Lorenz, X Guo, R Darlay, HJ Cordell, J He, ...
Nature genetics 54 (6), 761-771, 2022
1292022
Behavioural battery testing: evaluation and behavioural outcomes in 8 inbred mouse strains
HV Lad, L Liu, JL Paya-Cano, MJ Parsons, R Kember, C Fernandes, ...
Physiology & behavior 99 (3), 301-316, 2010
1232010
Limitations of contemporary guidelines for managing patients at high genetic risk of coronary artery disease
KG Aragam, A Dobbyn, R Judy, M Chaffin, K Chaudhary, G Hindy, ...
Journal of the American College of Cardiology 75 (22), 2769-2780, 2020
1222020
Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals
K Xu, B Li, KA McGinnis, R Vickers-Smith, C Dao, N Sun, RL Kember, ...
Nature communications 11 (1), 5302, 2020
1062020
Advancing paternal age is associated with deficits in social and exploratory behaviors in the offspring: a mouse model
RG Smith, RL Kember, J Mill, C Fernandes, LC Schalkwyk, JD Buxbaum, ...
PLoS One 4 (12), e8456, 2009
992009
Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate
B Georgi, D Craig, RL Kember, W Liu, I Lindquist, S Nasser, C Brown, ...
PLoS genetics 10 (3), e1004229, 2014
982014
The Penn Medicine BioBank: towards a genomics-enabled learning healthcare system to accelerate precision medicine in a diverse population
A Verma, SM Damrauer, N Naseer, JE Weaver, CM Kripke, L Guare, ...
Journal of Personalized Medicine 12 (12), 1974, 2022
812022
Association of inherited pathogenic variants in checkpoint kinase 2 (CHEK2) with susceptibility to testicular germ cell tumors
SH AlDubayan, LC Pyle, M Gamulin, T Kulis, ND Moore, A Taylor-Weiner, ...
JAMA oncology 5 (4), 514-522, 2019
732019
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Straipsniai 1–20