Naruhiko Sahara

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Dennis W. DicksonMayo ClinicPatvirtintas el. paštas mayo.edu
Ichio AokiNational Institutes for Quantum Science and Technology, QSTPatvirtintas el. paštas qst.go.jp
Sumihiro MaedaKeio University School of MedicinePatvirtintas el. paštas keio.jp
Yasuyuki KimuraNational Center for Geriatrics and GerontologyPatvirtintas el. paštas ncgg.go.jp
Virginia LeeProfessor of Pathology and Laboratory Medicine, University of PennsylvaniaPatvirtintas el. paštas upenn.edu
Keisuke Takahata, MD, PhDNational Institutes for Quantum Science and Technology (QST)Patvirtintas el. paštas qst.go.jp
Shunsuke KogaHospital of the University of PennsylvaniaPatvirtintas el. paštas pennmedicine.upenn.edu
Tara Spires-JonesUniversity of EdinburghPatvirtintas el. paštas ed.ac.uk
Bradley HymanMassachusetts General Hospital, Harvard Medical SchoolPatvirtintas el. paštas partners.org
Satoshi KuwabaraDepartment of Neurology, Chiba UniversityPatvirtintas el. paštas faculty.chiba-u.jp
Masayuki ShimojoShibaura Institute of TechnologyPatvirtintas el. paštas shibaura-it.ac.jp
Kazuto MasamotoUniv. of Electro-CommunicationsPatvirtintas el. paštas mce.uec.ac.jp
Ruiqing NiETH Zurich & University of ZurichPatvirtintas el. paštas biomed.ee.ethz.ch
Hideyuki OkanoKeio UniversityPatvirtintas el. paštas keio.jp
Marcelo Febo, PhDDepts of Psychiatry & Neuroscience, MBI, AMRIS, University of Florida College of MedicinePatvirtintas el. paštas ufl.edu
Shigeo MurataProfessor of Pharmaceutical Sciences, the University of TokyoPatvirtintas el. paštas mol.f.u-tokyo.ac.jp
Ryosuke TakahashiProfessor of Neurology, Kyoto University Graduate School of MedicinePatvirtintas el. paštas kuhp.kyoto-u.ac.jp
Truman Christopher GamblinProfessor of Biology, University of Texas at San AntonioPatvirtintas el. paštas utsa.edu

Stebėti

Naruhiko Sahara

National Institutes for Quantum Science and Technology, Japan

Patvirtintas el. paštas qst.go.jp

Alzheimer's Disease neurodegenerative diseases tau protein


Pavadinimas Rūšiuoti pagal šaltinius Rūšiuoti pagal metus Rūšiuoti pagal pavadinimą	Cituota Cituota	Metai
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP J Lewis, DW Dickson, WL Lin, L Chisholm, A Corral, G Jones, SH Yen, ... Science 293 (5534), 1487-1491, 2001	2134	2001
Propagation of tau pathology in a model of early Alzheimer's disease A De Calignon, M Polydoro, M Suárez-Calvet, C William, DH Adamowicz, ... Neuron 73 (4), 685-697, 2012	1612	2012
Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls M Maruyama, H Shimada, T Suhara, H Shinotoh, B Ji, J Maeda, ... Neuron 79 (6), 1094-1108, 2013	875	2013
Granular tau oligomers as intermediates of tau filaments S Maeda, N Sahara, Y Saito, M Murayama, Y Yoshiike, H Kim, T Miyasaka, ... Biochemistry 46 (12), 3856-3861, 2007	378	2007
Increased levels of granular tau oligomers: an early sign of brain aging and Alzheimer's disease S Maeda, N Sahara, Y Saito, S Murayama, A Ikai, A Takashima Neuroscience research 54 (3), 197-201, 2006	362	2006
Argyrophilic grain disease is a sporadic 4-repeat tauopathy T Togo, N Sahara, SH Yen, N Cookson, T Ishizawa, M Hutton, R De Silva, ... Journal of Neuropathology & Experimental Neurology 61 (6), 547-556, 2002	310	2002
In vivo evidence of CHIP up‐regulation attenuating tau aggregation N Sahara, M Murayama, T Mizoroki, M Urushitani, Y Imai, R Takahashi, ... Journal of neurochemistry 94 (5), 1254-1263, 2005	246	2005
Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies M Ono, N Sahara, K Kumata, B Ji, R Ni, S Koga, DW Dickson, ... Brain 140 (3), 764-780, 2017	240	2017
APP717 missense mutation affects the ratio of amyloid beta protein species (A beta 1-42/43 and a beta 1-40) in familial Alzheimer's disease brain A Tamaoka, A Odaka, Y Ishibashi, M Usami, N Sahara, N Suzuki, ... Journal of Biological Chemistry 269 (52), 32721-32724, 1994	238	1994
High-contrast in vivo imaging of tau pathologies in Alzheimer’s and non-Alzheimer’s disease tauopathies K Tagai, M Ono, M Kubota, S Kitamura, K Takahata, C Seki, Y Takado, ... Neuron 109 (1), 42-58. e8, 2021	236	2021
Assembly of two distinct dimers and higher‐order oligomers from full‐length tau N Sahara, S Maeda, M Murayama, T Suzuki, N Dohmae, SH Yen, ... European Journal of Neuroscience 25 (10), 3020-3029, 2007	222	2007
Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer’s disease A Sobue, O Komine, Y Hara, F Endo, H Mizoguchi, S Watanabe, ... Acta neuropathologica communications 9, 1-17, 2021	190	2021
Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild‐type human tau T Kimura, S Yamashita, T Fukuda, JM Park, M Murayama, T Mizoroki, ... The EMBO journal 26 (24), 5143-5152, 2007	174	2007
GSK-3β is required for memory reconsolidation in adult brain T Kimura, S Yamashita, S Nakao, JM Park, M Murayama, T Mizoroki, ... PloS one 3 (10), e3540, 2008	167	2008
Promotion of CHIP-mediated p53 degradation protects the heart from ischemic injury AT Naito, S Okada, T Minamino, K Iwanaga, ML Liu, T Sumida, S Nomura, ... Circulation research 106 (11), 1692-1702, 2010	163	2010
Biochemical evidence for the long-tail form (Aβ1-42/43) of amyloid β protein as a seed molecule in cerebral deposits of alzheimer′ s disease A Tamaoka, T Kondo, A Odaka, N Sahara, N Sawamura, K Ozawa, ... Biochemical and biophysical research communications 205 (1), 834-842, 1994	151	1994
Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility N Sahara, J Lewis, M DeTure, E McGowan, DW Dickson, M Hutton, ... Journal of neurochemistry 83 (6), 1498-1508, 2002	149	2002
Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607 Y Shi, AG Murzin, B Falcon, A Epstein, J Machin, P Tempest, KL Newell, ... Acta neuropathologica 141, 697-708, 2021	148	2021
Characteristics of TBS-extractable hyperphosphorylated tau species: aggregation intermediates in rTg4510 mouse brain N Sahara, M DeTure, Y Ren, AS Ebrahim, D Kang, J Knight, C Volbracht, ... Journal of Alzheimer’s disease 33 (1), 249-263, 2012	124	2012
PET quantification of tau pathology in human brain with 11C-PBB3 Y Kimura, M Ichise, H Ito, H Shimada, Y Ikoma, C Seki, H Takano, ... Journal of Nuclear Medicine 56 (9), 1359-1365, 2015	123	2015

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