RNA sequencing shows no dosage compensation of the active X-chromosome Y Xiong, X Chen, Z Chen, X Wang, S Shi, X Wang, J Zhang, X He Nature genetics 42 (12), 1043-1047, 2010 | 225 | 2010 |
Codon-by-codon modulation of translational speed and accuracy via mRNA folding JR Yang, X Chen, J Zhang PLoS Biol 12 (7), e1001910, 2014 | 127 | 2014 |
Differential requirements for mRNA folding partially explain why highly expressed proteins evolve slowly C Park, X Chen, JR Yang, J Zhang Proceedings of the National Academy of Sciences 110 (8), E678-E686, 2013 | 124 | 2013 |
Nucleosomes suppress spontaneous mutations base-specifically in eukaryotes X Chen, Z Chen, H Chen, Z Su, J Yang, F Lin, S Shi, X He Science 335 (6073), 1235-1238, 2012 | 111 | 2012 |
The ortholog conjecture is untestable by the current gene ontology but is supported by RNA sequencing data X Chen, J Zhang PLoS Comput Biol 8 (11), e1002784, 2012 | 99 | 2012 |
The genomic landscape of position effects on protein expression level and noise in yeast X Chen, J Zhang Cell systems 2 (5), 347-354, 2016 | 98 | 2016 |
Dissimilation of synonymous codon usage bias in virus–host coevolution due to translational selection F Chen, P Wu, S Deng, H Zhang, Y Hou, Z Hu, J Zhang, X Chen, JR Yang Nature ecology & evolution 4 (4), 589-600, 2020 | 97 | 2020 |
No gene-specific optimization of mutation rate in Escherichia coli X Chen, J Zhang Molecular biology and evolution 30 (7), 1559-1562, 2013 | 68 | 2013 |
Population genetics of speciation in nonmodel organisms: I. Ancestral polymorphism in mangroves R Zhou, K Zeng, W Wu, X Chen, Z Yang, S Shi, CI Wu Molecular Biology and Evolution 24 (12), 2746-2754, 2007 | 62 | 2007 |
No X-chromosome dosage compensation in human proteomes X Chen, J Zhang Molecular biology and evolution 32 (6), 1456-1460, 2015 | 41 | 2015 |
Gene expression profiles in response to salt stress in Hibiscus tiliaceus G Yang, R Zhou, T Tang, X Chen, J Ouyang, L He, W Li, S Chen, M Guo, ... Plant Molecular Biology Reporter 29 (3), 609-617, 2011 | 40 | 2011 |
Expression level is a major modifier of the fitness landscape of a protein coding gene Z Wu, X Cai, X Zhang, Y Liu, G Tian, JR Yang, X Chen Nature ecology & evolution, 1-13, 2021 | 30 | 2021 |
Why are genes encoded on the lagging strand of the bacterial genome? X Chen, J Zhang Genome biology and evolution 5 (12), 2436-2439, 2013 | 30 | 2013 |
He et al. reply X He, X Chen, Y Xiong, Z Chen, X Wang, S Shi, X Wang, J Zhang Nature Genetics 43 (12), 1171-1172, 2011 | 30 | 2011 |
Reduced intrinsic DNA curvature leads to increased mutation rate C Duan, Q Huan, X Chen, S Wu, LB Carey, X He, W Qian Genome biology 19 (1), 1-12, 2018 | 29 | 2018 |
Nascent RNA folding mitigates transcription-associated mutagenesis X Chen, JR Yang, J Zhang Genome research 26 (1), 50-59, 2016 | 28 | 2016 |
Mutation accumulation experiment supports elevated mutation rates at highly transcribed sites X Chen, J Zhang Proc. Natl. Acad. Sci. USA 111 (E4062), 2014 | 24* | 2014 |
The evolution of sex chromosome dosage compensation in animals J Chen, M Wang, X He, JR Yang, X Chen Journal of Genetics and Genomics 47 (11), 681-693, 2020 | 21 | 2020 |
The X to autosome expression ratio in haploid and diploid human embryonic stem cells X Chen, J Zhang Molecular biology and evolution 33 (12), 3104-3107, 2016 | 18 | 2016 |
Alignment of cell lineage trees elucidates genetic programs for the development and evolution of cell types M Yuan, X Yang, J Lin, X Cao, F Chen, X Zhang, Z Li, G Zheng, X Wang, ... Iscience 23 (7), 101273, 2020 | 13 | 2020 |