β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis J Rosenbluh, D Nijhawan, AG Cox, X Li, JT Neal, EJ Schafer, TI Zack, ... Cell 151 (7), 1457-1473, 2012 | 867 | 2012 |
Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling AG Cox, CC Winterbourn, MB Hampton Biochemical Journal 425 (2), 313-325, 2010 | 600 | 2010 |
Mitochondrial dysfunction remodels one-carbon metabolism in human cells XR Bao, SE Ong, O Goldberger, J Peng, R Sharma, DA Thompson, ... elife 5, e10575, 2016 | 371 | 2016 |
Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth AG Cox, KL Hwang, KK Brown, KJ Evason, S Beltz, A Tsomides, ... Nature cell biology 18 (8), 886-896, 2016 | 223 | 2016 |
The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation AG Cox, KK Brown, ESJ Arner, MB Hampton Biochemical pharmacology 76 (9), 1097-1109, 2008 | 210 | 2008 |
Redox potential and peroxide reactivity of human peroxiredoxin 3 AG Cox, AV Peskin, LN Paton, CC Winterbourn, MB Hampton Biochemistry 48 (27), 6495-6501, 2009 | 147 | 2009 |
Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo JM Harris, V Esain, GM Frechette, LJ Harris, AG Cox, M Cortes, ... Blood, The Journal of the American Society of Hematology 121 (13), 2483-2493, 2013 | 132 | 2013 |
Mitochondrial peroxiredoxin 3 is more resilient to hyperoxidation than cytoplasmic peroxiredoxins AG Cox, AG Pearson, JM Pullar, TJ Jönsson, WT Lowther, ... Biochemical Journal 421 (1), 51-58, 2009 | 127 | 2009 |
Estrogen activation of G-protein–coupled estrogen receptor 1 regulates phosphoinositide 3-kinase and mTOR signaling to promote liver growth in zebrafish and proliferation of … S Chaturantabut, A Shwartz, KJ Evason, AG Cox, K Labella, AG Schepers, ... Gastroenterology 156 (6), 1788-1804. e13, 2019 | 110 | 2019 |
Measuring the redox state of cellular peroxiredoxins by immunoblotting AG Cox, CC Winterbourn, MB Hampton Methods in enzymology 474, 51-66, 2010 | 106 | 2010 |
Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth AG Cox, A Tsomides, D Yimlamai, KL Hwang, J Miesfeld, GG Galli, ... The EMBO journal 37 (22), e100294, 2018 | 98 | 2018 |
Oxidation of mitochondrial peroxiredoxin 3 during the initiation of receptor-mediated apoptosis AG Cox, JM Pullar, G Hughes, EC Ledgerwood, MB Hampton Free Radical Biology and Medicine 44 (6), 1001-1009, 2008 | 97 | 2008 |
YAP regulates hematopoietic stem cell formation in response to the biomechanical forces of blood flow V Lundin, WW Sugden, LN Theodore, PM Sousa, A Han, S Chou, ... Developmental cell 52 (4), 446-460. e5, 2020 | 87 | 2020 |
Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis AG Cox, A Tsomides, AJ Kim, D Saunders, KL Hwang, KJ Evason, ... Proceedings of the National Academy of Sciences 113 (38), E5562-E5571, 2016 | 74 | 2016 |
S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury AG Cox, DC Saunders, PB Kelsey, AA Conway, Y Tesmenitsky, ... Cell reports 6 (1), 56-69, 2014 | 64 | 2014 |
Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3 AV Peskin, AG Cox, P Nagy, PE Morgan, MB Hampton, MJ Davies, ... Biochemical Journal 432 (2), 313-321, 2010 | 60 | 2010 |
The lure of zebrafish in liver research: regulation of hepatic growth in development and regeneration AG Cox, W Goessling Current opinion in genetics & development 32, 153-161, 2015 | 57 | 2015 |
Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer S Nissim, I Leshchiner, JD Mancias, MB Greenblatt, O Maertens, ... Nature Genetics 51 (9), 1308-1314, 2019 | 55 | 2019 |
Mitochondrial respiratory chain involvement in peroxiredoxin 3 oxidation by phenethyl isothiocyanate and auranofin KK Brown, AG Cox, MB Hampton FEBS letters 584 (6), 1257-1262, 2010 | 50 | 2010 |
Release and clinical significance of soluble CD83 in chronic lymphocytic leukemia BD Hock, LJ Fernyhough, SM Gough, A Steinkasserer, AG Cox, ... Leukemia research 33 (8), 1089-1095, 2009 | 39 | 2009 |