Stebėti
Ron Diskin
Ron Diskin
Department of Chemical and Structural Biology Weizmann Institute of Science
Patvirtintas el. paštas weizmann.ac.il
Pavadinimas
Cituota
Cituota
Metai
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding
JF Scheid, H Mouquet, B Ueberheide, R Diskin, F Klein, TYK Oliveira, ...
Science 333 (6049), 1633-1637, 2011
13882011
Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization
F Klein, R Diskin, JF Scheid, C Gaebler, H Mouquet, IS Georgiev, ...
Cell 153 (1), 126-138, 2013
6582013
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
F Klein, A Halper-Stromberg, JA Horwitz, H Gruell, JF Scheid, ...
Nature 492 (7427), 118-122, 2012
5962012
Increasing the potency and breadth of an HIV antibody by using structure-based rational design
R Diskin, JF Scheid, PM Marcovecchio, AP West Jr, F Klein, H Gao, ...
Science 334 (6060), 1289-1293, 2011
4452011
Longitudinal isolation of potent near-germline SARS-CoV-2-neutralizing antibodies from COVID-19 patients
C Kreer, M Zehner, T Weber, MS Ercanoglu, L Gieselmann, C Rohde, ...
Cell 182 (4), 843-854. e12, 2020
3922020
Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques
M Shingai, OK Donau, RJ Plishka, A Buckler-White, JR Mascola, ...
Journal of Experimental Medicine 211 (10), 2061-2074, 2014
3732014
Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120
AP West Jr, R Diskin, MC Nussenzweig, PJ Bjorkman
Proceedings of the National Academy of Sciences 109 (30), E2083-E2090, 2012
2702012
Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs
S Hoot, AT McGuire, KW Cohen, RK Strong, L Hangartner, F Klein, ...
PLoS pathogens 9 (1), e1003106, 2013
2302013
Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity
R Diskin, PM Marcovecchio, PJ Bjorkman
Nature structural & molecular biology 17 (5), 608-613, 2010
1332010
Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV
SA Ehrhardt, M Zehner, V Krähling, H Cohen-Dvashi, C Kreer, N Elad, ...
Nature medicine 25 (10), 1589-1600, 2019
1202019
Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces
S Warszawski, A Borenstein Katz, R Lipsh, L Khmelnitsky, G Ben Nissan, ...
PLoS computational biology 15 (8), e1007207, 2019
1192019
Assembly mechanism of mucin and von Willebrand factor polymers
G Javitt, L Khmelnitsky, L Albert, LS Bigman, N Elad, D Morgenstern, ...
Cell 183 (3), 717-729. e16, 2020
1132020
Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies
R Diskin, F Klein, JA Horwitz, A Halper-Stromberg, DN Sather, ...
Journal of Experimental Medicine 210 (6), 1235-1249, 2013
1072013
Molecular mechanism for LAMP1 recognition by Lassa virus
H Cohen-Dvashi, N Cohen, H Israeli, R Diskin
Journal of virology 89 (15), 7584-7592, 2015
992015
A mouse model for HIV-1 entry
J Pietzsch, H Gruell, S Bournazos, BM Donovan, F Klein, R Diskin, ...
Proceedings of the National Academy of Sciences 109 (39), 15859-15864, 2012
932012
Structures of p38α active mutants reveal conformational changes in L16 loop that induce autophosphorylation and activation
R Diskin, M Lebendiker, D Engelberg, O Livnah
Journal of molecular biology 365 (1), 66-76, 2007
922007
Active mutants of the human p38α mitogen-activated protein kinase
R Diskin, N Askari, R Capone, D Engelberg, O Livnah
Journal of Biological Chemistry 279 (45), 47040-47049, 2004
882004
Intrinsically active variants of all human p38 isoforms
M Avitzour, R Diskin, B Raboy, N Askari, D Engelberg, O Livnah
The FEBS journal 274 (4), 963-975, 2007
832007
Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody
L Scharf, AP West Jr, H Gao, T Lee, JF Scheid, MC Nussenzweig, ...
Proceedings of the National Academy of Sciences 110 (15), 6049-6054, 2013
822013
Role of LAMP1 binding and pH sensing by the spike complex of Lassa virus
H Cohen-Dvashi, H Israeli, O Shani, A Katz, R Diskin
Journal of virology 90 (22), 10329-10338, 2016
732016
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Straipsniai 1–20