Crystal structure of the peroxisome proliferator-activated receptor γ (PPARγ) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic … R Montanari, F Saccoccia, E Scotti, M Crestani, C Godio, F Gilardi, ... Journal of medicinal chemistry 51 (24), 7768-7776, 2008 | 130 | 2008 |
Resveratrol and its metabolites bind to PPARs E Calleri, G Pochetti, KSS Dossou, A Laghezza, R Montanari, D Capelli, ... ChemBioChem 15 (8), 1154-1160, 2014 | 107 | 2014 |
Structural basis for PPAR partial or full activation revealed by a novel ligand binding mode D Capelli, C Cerchia, R Montanari, F Loiodice, P Tortorella, A Laghezza, ... Scientific reports 6 (1), 34792, 2016 | 101 | 2016 |
Extra Binding Region Induced by Non-Zinc Chelating Inhibitors into the S1′ Subsite of Matrix Metalloproteinase 8 (MMP-8) G Pochetti, R Montanari, C Gege, C Chevrier, AG Taveras, F Mazza Journal of medicinal chemistry 52 (4), 1040-1049, 2009 | 96 | 2009 |
Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis G Brusotti, R Montanari, D Capelli, G Cattaneo, A Laghezza, P Tortorella, ... Scientific reports 7 (1), 5777, 2017 | 84 | 2017 |
Surface plasmon resonance technology: Recent advances, applications and experimental cases D Capelli, V Scognamiglio, R Montanari TrAC Trends in Analytical Chemistry 163, 117079, 2023 | 79 | 2023 |
Structural insight into peroxisome proliferator-activated receptor γ binding of two ureidofibrate-like enantiomers by molecular dynamics, cofactor interaction analysis, and … G Pochetti, N Mitro, A Lavecchia, F Gilardi, N Besker, E Scotti, M Aschi, ... Journal of medicinal chemistry 53 (11), 4354-4366, 2010 | 58 | 2010 |
Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity L Porcelli, F Gilardi, A Laghezza, L Piemontese, N Mitro, A Azzariti, ... Journal of medicinal chemistry 55 (1), 37-54, 2012 | 56 | 2012 |
New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors α/γ dual agonists with improved potency and reduced adverse effects on skeletal muscle … G Fracchiolla, A Laghezza, L Piemontese, P Tortorella, F Mazza, ... Journal of medicinal chemistry 52 (20), 6382-6393, 2009 | 50 | 2009 |
Green approach for the fabrication of silver-oxidized cellulose nanocomposite with antibacterial properties D Caschera, RG Toro, F Federici, R Montanari, T de Caro, MT Al-Shemy, ... Cellulose 27, 8059-8073, 2020 | 49 | 2020 |
Fabrication of packaging paper sheets decorated with alginate/oxidized nanocellulose‑silver nanoparticles bio-nanocomposite AM Adel, MT Al-Shemy, MA Diab, M El-Sakhawy, RG Toro, R Montanari, ... International Journal of Biological Macromolecules 181, 612-620, 2021 | 46 | 2021 |
The investigation on cationic exchange capacity of zeolites: The use as selective ion trappers in the electrokinetic soil technique O Ursini, E Lilla, R Montanari Journal of hazardous materials 137 (2), 1079-1088, 2006 | 45 | 2006 |
New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor α/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression A Laghezza, G Pochetti, A Lavecchia, G Fracchiolla, S Faliti, ... Journal of Medicinal Chemistry 56 (1), 60-72, 2013 | 41 | 2013 |
Surface plasmon resonance as a tool for ligand binding investigation of engineered GPR17 receptor, a G protein coupled receptor involved in myelination D Capelli, C Parravicini, G Pochetti, R Montanari, C Temporini, ... Frontiers in chemistry 7, 910, 2020 | 39 | 2020 |
Frontal affinity chromatography with MS detection of the ligand binding domain of PPARγ receptor: ligand affinity screening and stereoselective ligand–macromolecule interaction E Calleri, G Fracchiolla, R Montanari, G Pochetti, A Lavecchia, F Loiodice, ... Journal of Chromatography A 1232, 84-92, 2012 | 36 | 2012 |
Identification of the first PPARα/γ dual agonist able to bind to canonical and alternative sites of PPARγ and to inhibit its cdk5-mediated phosphorylation A Laghezza, L Piemontese, C Cerchia, R Montanari, D Capelli, M Giudici, ... Journal of Medicinal Chemistry 61 (18), 8282-8298, 2018 | 33 | 2018 |
Catechol-based matrix metalloproteinase inhibitors with additional antioxidative activity M Tauro, A Laghezza, F Loiodice, L Piemontese, A Caradonna, D Capelli, ... Journal of Enzyme Inhibition and Medicinal Chemistry 31 (sup4), 25-37, 2016 | 33 | 2016 |
On the Metabolically Active Form of Metaglidasen: Improved Synthesis and Investigation of Its Peculiar Activity on Peroxisome Proliferator‐Activated Receptors and Skeletal Muscles A Laghezza, R Montanari, A Lavecchia, L Piemontese, G Pochetti, ... ChemMedChem 10 (3), 555-565, 2015 | 33 | 2015 |
Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors α/γ dual agonists G Fracchiolla, A Laghezza, L Piemontese, M Parente, A Lavecchia, ... Bioorganic & medicinal chemistry 20 (6), 2141-2151, 2012 | 30 | 2012 |
Insights into PPARγ phosphorylation and its inhibition mechanism R Montanari, D Capelli, K Yamamoto, H Awaishima, K Nishikata, ... Journal of Medicinal Chemistry 63 (9), 4811-4823, 2020 | 28 | 2020 |