Subtype and pathway specific responses to anticancer compounds in breast cancer LM Heiser, A Sadanandam, WL Kuo, SC Benz, TC Goldstein, S Ng, ... Proceedings of the National Academy of Sciences 109 (8), 2724-2729, 2012 | 552 | 2012 |
The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ... Cell systems 6 (1), 13-24, 2018 | 441 | 2018 |
Bladder cancer outcome and subtype classification by gene expression E Blaveri, JP Simko, JE Korkola, JL Brewer, F Baehner, K Mehta, ... Clinical Cancer Research 11 (11), 4044-4055, 2005 | 383 | 2005 |
A central role for RAF→ MEK→ ERK signaling in the genesis of pancreatic ductal adenocarcinoma EA Collisson, CL Trejo, JM Silva, S Gu, JE Korkola, LM Heiser, ... Cancer discovery 2 (8), 685-693, 2012 | 365 | 2012 |
Down-regulation of stem cell genes, including those in a 200-kb gene cluster at 12p13. 31, is associated with in vivo differentiation of human male germ cell tumors JE Korkola, J Houldsworth, RSV Chadalavada, AB Olshen, D Dobrzynski, ... Cancer research 66 (2), 820-827, 2006 | 349 | 2006 |
Modeling precision treatment of breast cancer A Daemen, OL Griffith, LM Heiser, NJ Wang, OM Enache, Z Sanborn, ... Genome biology 14, 1-14, 2013 | 343 | 2013 |
Array-based comparative genomic hybridization for genome-wide screening of DNA copy number in bladder tumors JA Veltman, J Fridlyand, S Pejavar, AB Olshen, JE Korkola, S DeVries, ... Cancer research 63 (11), 2872-2880, 2003 | 315 | 2003 |
Differentiation of lobular versus ductal breast carcinomas by expression microarray analysis JE Korkola, S DeVries, J Fridlyand, ES Hwang, ALH Estep, YY Chen, ... Cancer research 63 (21), 7167-7175, 2003 | 284 | 2003 |
Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival CE Gast, AD Silk, L Zarour, L Riegler, JG Burkhart, KT Gustafson, ... Science advances 4 (9), eaat7828, 2018 | 277 | 2018 |
Modeling tumor phenotypes in vitro with three-dimensional bioprinting EM Langer, BL Allen-Petersen, SM King, ND Kendsersky, MA Turnidge, ... Cell reports 26 (3), 608-623. e6, 2019 | 249 | 2019 |
Clonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma E Shelley Hwang, SJ Nyante, Y Yi Chen, D Moore, S DeVries, JE Korkola, ... Cancer 100 (12), 2562-2572, 2004 | 203 | 2004 |
Exome sequencing of cell-free DNA from metastatic cancer patients identifies clinically actionable mutations distinct from primary disease TM Butler, K Johnson-Camacho, M Peto, NJ Wang, TA Macey, JE Korkola, ... PloS one 10 (8), e0136407, 2015 | 143 | 2015 |
CCR5 governs DNA damage repair and breast cancer stem cell expansion X Jiao, MA Velasco-Velazquez, M Wang, Z Li, H Rui, AR Peck, JE Korkola, ... Cancer research 78 (7), 1657-1671, 2018 | 138 | 2018 |
Cellular senescence in cancer: from mechanisms to detection HL Ou, R Hoffmann, C González‐López, GJ Doherty, JE Korkola, ... Molecular oncology 15 (10), 2634-2671, 2021 | 137 | 2021 |
A multi-center study on the reproducibility of drug-response assays in mammalian cell lines M Niepel, M Hafner, CE Mills, K Subramanian, EH Williams, M Chung, ... Cell systems 9 (1), 35-48. e5, 2019 | 135 | 2019 |
A genetic strategy for single and combinatorial analysis of miRNA function in mammalian hematopoietic stem cells EP Papapetrou, JE Korkola, M Sadelain Stem cells 28 (2), 287-296, 2010 | 107 | 2010 |
Breast cancer genomes—form and function J Korkola, JW Gray Current opinion in genetics & development 20 (1), 4-14, 2010 | 104 | 2010 |
Identification and validation of a gene expression signature that predicts outcome in adult men with germ cell tumors JE Korkola, J Houldsworth, DR Feldman, AB Olshen, LX Qin, S Patil, ... Journal of clinical oncology 27 (31), 5240-5247, 2009 | 94 | 2009 |
Kinome rewiring reveals AURKA limits PI3K-pathway inhibitor efficacy in breast cancer HJ Donnella, JT Webber, RS Levin, R Camarda, O Momcilovic, N Bayani, ... Nature chemical biology 14 (8), 768-777, 2018 | 92 | 2018 |
Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib A Daemen, DM Wolf, JE Korkola, OL Griffith, JR Frankum, R Brough, ... Breast cancer research and treatment 135, 505-517, 2012 | 91 | 2012 |