Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach AK Krug, R Kolde, JA Gaspar, E Rempel, NV Balmer, K Meganathan, ... Archives of toxicology 87, 123-143, 2013 | 253 | 2013 |
Chemoprotective mechanism of the natural compounds, epigallocatechin-3-O-gallate, quercetin and curcumin against cancer and cardiovascular diseases S Jagtap, K Meganathan, V Wagh, J Winkler, J Hescheler, A Sachinidis Current medicinal chemistry 16 (12), 1451-1462, 2009 | 233 | 2009 |
Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells B Zimmer, G Lee, NV Balmer, K Meganathan, A Sachinidis, L Studer, ... Environmental health perspectives 120 (8), 1116-1122, 2012 | 125 | 2012 |
Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue P Godoy, A Widera, W Schmidt-Heck, G Campos, C Meyer, C Cadenas, ... Archives of toxicology 90, 2513-2529, 2016 | 121 | 2016 |
Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells K Meganathan, S Jagtap, V Wagh, J Winkler, JA Gaspar, D Hildebrand, ... Public Library of Science 7 (8), e44228, 2012 | 100 | 2012 |
From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug … NV Balmer, S Klima, E Rempel, VN Ivanova, R Kolde, MK Weng, ... Archives of toxicology 88, 1451-1468, 2014 | 81 | 2014 |
Development of a neural teratogenicity test based on human embryonic stem cells: response to retinoic acid exposure S Colleoni, C Galli, JA Gaspar, K Meganathan, S Jagtap, J Hescheler, ... Toxicological sciences 124 (2), 370-377, 2011 | 70 | 2011 |
Mesoderm-derived stem cells: the link between the transcriptome and their differentiation potential J De Kock, M Najar, J Bolleyn, F Al Battah, RM Rodrigues, K Buyl, ... Stem cells and development 21 (18), 3309-3323, 2012 | 65 | 2012 |
Signaling molecules, transcription growth factors and other regulators revealed from in-vivo and in-vitro models for the regulation of cardiac development K Meganathan, I Sotiriadou, K Natarajan, J Hescheler, A Sachinidis International journal of cardiology 183, 117-128, 2015 | 64 | 2015 |
Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Tox ukn and STOP-Tox ukk tests V Shinde, L Hoelting, SP Srinivasan, J Meisig, K Meganathan, S Jagtap, ... Archives of toxicology 91, 839-864, 2017 | 62 | 2017 |
Effects of cryopreservation on the transcriptome of human embryonic stem cells after thawing and culturing V Wagh, K Meganathan, S Jagtap, JA Gaspar, J Winkler, D Spitkovsky, ... Stem Cell Reviews and Reports 7, 506-517, 2011 | 59 | 2011 |
Human pluripotent stem cell based developmental toxicity assays for chemical safety screening and systems biology data generation V Shinde, S Klima, PS Sureshkumar, K Meganathan, S Jagtap, E Rempel, ... Journal of visualized experiments: JoVE, 52333, 2015 | 56 | 2015 |
Regulation of liver metabolism by the endosomal GTPase Rab5 A Zeigerer, RL Bogorad, K Sharma, J Gilleron, S Seifert, S Sales, ... Cell reports 11 (6), 884-892, 2015 | 56 | 2015 |
Human skin-derived stem cells as a novel cell source for in vitro hepatotoxicity screening of pharmaceuticals RM Rodrigues, J De Kock, S Branson, M Vinken, K Meganathan, ... Stem cells and development 23 (1), 44-55, 2014 | 56 | 2014 |
Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development K Meganathan, EMA Lewis, P Gontarz, S Liu, EG Stanley, AG Elefanty, ... Proceedings of the National Academy of Sciences 114 (52), E11180-E11189, 2017 | 51 | 2017 |
Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells K Meganathan, S Jagtap, SP Srinivasan, V Wagh, J Hescheler, ... Cell death & disease 6 (5), e1756-e1756, 2015 | 50 | 2015 |
Cytosine arabinoside induces ectoderm and inhibits mesoderm expression in human embryonic stem cells during multilineage differentiation S Jagtap, K Meganathan, J Gaspar, V Wagh, J Winkler, J Hescheler, ... British journal of pharmacology 162 (8), 1743-1756, 2011 | 49 | 2011 |
Balancing serendipity and reproducibility: Pluripotent stem cells as experimental systems for intellectual and developmental disorders NC Anderson, PF Chen, K Meganathan, WA Saber, AJ Petersen, ... Stem cell reports 16 (6), 1446-1457, 2021 | 35 | 2021 |
Neuronal-Specific Deficiency of the Splicing Factor Tra2b Causes Apoptosis in Neurogenic Areas of the Developing Mouse Brain M Storbeck, K Hupperich, JA Gaspar, K Meganathan, L Martínez Carrera, ... PLoS One 9 (2), e89020, 2014 | 32 | 2014 |
Complexities of X chromosome inactivation status in female human induced pluripotent stem cells—a brief review and scientific update for autism research MG Dandulakis, K Meganathan, KL Kroll, A Bonni, JN Constantino Journal of neurodevelopmental disorders 8, 1-7, 2016 | 30 | 2016 |