| Purification and characterization of a newly identified growth factor specific for epithelial cells. JS Rubin, H Osada, PW Finch, WG Taylor, S Rudikoff, SA Aaronson Proceedings of the National Academy of Sciences 86 (3), 802-806, 1989 | 1162 | 1989 |
| In vivo destabilization of dynamic microtubules by HDAC6‐mediated deacetylation A Matsuyama, T Shimazu, Y Sumida, A Saito, Y Yoshimatsu, ... The EMBO journal, 2002 | 871 | 2002 |
| Novel mammalian cell cycle inhibitors, spirotryprostatins A and B, produced by Aspergillus fumigatus, which inhibit mammalian cell cycle at G2/M phase CB Cui, H Kakeya, H Osada Tetrahedron 52 (39), 12651-12666, 1996 | 665 | 1996 |
| M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFβ-TrCP N Watanabe, H Arai, Y Nishihara, M Taniguchi, N Watanabe, T Hunter, ... Proceedings of the National Academy of Sciences 101 (13), 4419-4424, 2004 | 643 | 2004 |
| Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-κB ligand (RANKL) M Matsumoto, T Sudo, T Saito, H Osada, M Tsujimoto Journal of Biological Chemistry 275 (40), 31155-31161, 2000 | 636 | 2000 |
| Spirotryprostatin B, a novel mammalian cell cycle inhibitor produced by Aspergillus fumigatus CB Cui, H Kakeya, H Osada The Journal of Antibiotics 49 (8), 832-835, 1996 | 380 | 1996 |
| Novel Mammalian Cell Cycle Inhibitors, Tryprostatins A, B and Other Diketopiperazines Produced by Aspergillus Fumigatus I. Taxonomy, Fermentation, Isolation and Biological … CB Cui, H Kakeya, G Okada, R Onose, H Osada The Journal of antibiotics 49 (6), 527-533, 1996 | 334 | 1996 |
| Tryprostatin A, a specific and novel inhibitor of microtubule assembly T Usui, M Kondoh, CB Cui, T Mayumi, H OSADA Biochemical Journal 333 (3), 543-548, 1998 | 287 | 1998 |
| Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways N Watanabe, H Arai, J Iwasaki, M Shiina, K Ogata, T Hunter, H Osada Proceedings of the National Academy of Sciences 102 (33), 11663-11668, 2005 | 281 | 2005 |
| Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis V Temkin, Q Huang, H Liu, H Osada, RM Pope Molecular and cellular biology 26 (6), 2215-2225, 2006 | 244 | 2006 |
| A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning N Takahashi-Ando, M Kimura, H Kakeya, H Osada, I Yamaguchi Biochemical journal 365 (1), 1-6, 2002 | 240 | 2002 |
| Immobilization of natural products on glass slides by using a photoaffinity reaction and the detection of protein-small-molecule interactions N Kanoh, S Kumashiro, S Simizu, Y Kondoh, S Hatakeyama, H Tashiro, ... Angewandte Chemie-International Edition 42 (45), 5584-5587, 2003 | 219 | 2003 |
| Novel mammalian cell cycle inhibitors, cyclotroprostatins A–D, produced by Aspergillus fumigatus, which inhibit mammalian cell cycle at G2/M phase CB Cui, H Kakeya, H Osada Tetrahedron 53 (1), 59-72, 1997 | 217 | 1997 |
| Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus II. Physico-chemical properties and structures CB Cui, H Kakeya, H Osada The Journal of antibiotics 49 (6), 534-540, 1996 | 209 | 1996 |
| RK-682, a potent inhibitor of tyrosine phosphatase, arrested the mammalian cell cycle progression at G1phase T Hamaguchi, T Sudo, H Osada FEBS letters 372 (1), 54-58, 1995 | 200 | 1995 |
| Tryprostatins A and B, novel mammalian cell cycle inhibitors produced by Aspergillus fumigatus CB Cui, H KAKEYA, GEN Okada, RIE Onose, M UBUKATA, I TAKAHASHI, ... The Journal of antibiotics 48 (11), 1382-1384, 1995 | 197 | 1995 |
| Epolactaene, a novel neuritogenic compound in human neuroblastoma cells, produced by a marine fungus H KAKEYA, I TAKAHASHI, GEN OKADA, K ISONO, H OSADA The Journal of Antibiotics 48 (7), 733-735, 1995 | 187 | 1995 |
| Laforin, defective in the progressive myoclonus epilepsy of Lafora type, is a dual-specificity phosphatase associated with polyribosomes S Ganesh, KL Agarwala, K Ueda, T Akagi, K Shoda, T Usui, T Hashikawa, ... Human molecular genetics 9 (15), 2251-2261, 2000 | 184 | 2000 |
| Cytoxazone: A Novel Cytokine Modulator Containing a 2-Oxazolidinone Ring Produced by Streptomyces sp. H Kakeya, M Morishita, H Koshino, T Morita, K Kobayashi, H Osada The Journal of Organic Chemistry 64 (3), 1052-1053, 1999 | 184 | 1999 |
| Azaspirene: A Novel Angiogenesis Inhibitor Containing a 1-Oxa-7-azaspiro[4.4]non-2-ene-4,6-dione Skeleton Produced by the Fungus Neosartorya sp. Y Asami, H Kakeya, R Onose, A Yoshida, H Matsuzaki, H Osada Organic letters 4 (17), 2845-2848, 2002 | 177 | 2002 |
Takeo UsuiUniversity of TsukubaPatvirtintas el. paštas u.tsukuba.ac.jp