Ivermectin–old drug, new tricks? R Laing, V Gillan, E Devaney Trends in parasitology 33 (6), 463-472, 2017 | 491 | 2017 |
The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery R Laing, T Kikuchi, A Martinelli, IJ Tsai, RN Beech, E Redman, N Holroyd, ... Genome biology 14, 1-16, 2013 | 392 | 2013 |
Refugia and anthelmintic resistance: concepts and challenges JE Hodgkinson, RM Kaplan, F Kenyon, ER Morgan, AW Park, S Paterson, ... International Journal for Parasitology: Drugs and Drug Resistance 10, 51-57, 2019 | 142 | 2019 |
Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm SR Doyle, A Tracey, R Laing, N Holroyd, D Bartley, W Bazant, H Beasley, ... Communications biology 3 (1), 656, 2020 | 140 | 2020 |
Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus SR Doyle, CJR Illingworth, R Laing, DJ Bartley, E Redman, A Martinelli, ... BMC genomics 20, 1-19, 2019 | 95 | 2019 |
Characterization of the xenobiotic response of Caenorhabditis elegans to the anthelmintic drug albendazole and the identification of novel drug glucoside metabolites ST Laing, A Ivens, R Laing, S Ravikumar, V Butler, DJ Woods, JS Gilleard Biochemical Journal 432 (3), 505-516, 2010 | 91 | 2010 |
Characterization and comparative analysis of the complete Haemonchus contortus β-tubulin gene family and implications for benzimidazole resistance in strongylid nematodes GI Saunders, JD Wasmuth, R Beech, R Laing, M Hunt, H Naghra, ... International journal for parasitology 43 (6), 465-475, 2013 | 81 | 2013 |
The cytochrome P450 family in the parasitic nematode Haemonchus contortus R Laing, DJ Bartley, AA Morrison, A Rezansoff, A Martinelli, ST Laing, ... International journal for parasitology 45 (4), 243-251, 2015 | 75 | 2015 |
A genome resequencing-based genetic map reveals the recombination landscape of an outbred parasitic nematode in the presence of polyploidy and polyandry SR Doyle, R Laing, DJ Bartley, C Britton, U Chaudhry, JS Gilleard, ... Genome Biology and Evolution 10 (2), 396-409, 2018 | 69 | 2018 |
Genomic landscape of drug response reveals mediators of anthelmintic resistance SR Doyle, R Laing, D Bartley, A Morrison, N Holroyd, K Maitland, ... Cell Reports 41 (3), 2022 | 63* | 2022 |
The Transcriptional Response of Caenorhabditis elegans to Ivermectin Exposure Identifies Novel Genes Involved in the Response to Reduced Food Intake ST Laing, A Ivens, V Butler, SP Ravikumar, R Laing, DJ Woods, ... PloS one 7 (2), e31367, 2012 | 55 | 2012 |
UDP-glycosyltransferase family in Haemonchus contortus: phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences P Matoušková, L Lecová, R Laing, D Dimunová, H Vogel, LR Stuchlíková, ... International Journal for Parasitology: Drugs and Drug Resistance 8 (3), 420-429, 2018 | 48 | 2018 |
Evidence from two independent backcross experiments supports genetic linkage of microsatellite Hcms8a20, but not other candidate loci, to a major ivermectin resistance locus in … AM Rezansoff, R Laing, JS Gilleard International journal for parasitology 46 (10), 653-661, 2016 | 45 | 2016 |
Evaluation of DNA extraction methods on individual helminth egg and larval stages for whole-genome sequencing SR Doyle, G Sankaranarayanan, F Allan, D Berger, PD Jimenez Castro, ... Frontiers in Genetics 10, 826, 2019 | 41 | 2019 |
Small RNAs in parasitic nematodes–forms and functions C Britton, R Laing, E Devaney Parasitology 147 (8), 855-864, 2020 | 37 | 2020 |
Haemonchus contortus: genome structure, organization and comparative genomics R Laing, A Martinelli, A Tracey, N Holroyd, JS Gilleard, JA Cotton Advances in Parasitology 93, 569-598, 2016 | 34 | 2016 |
Increased expression of a microRNA correlates with anthelmintic resistance in parasitic nematodes V Gillan, K Maitland, R Laing, H Gu, ND Marks, AD Winter, D Bartley, ... Frontiers in Cellular and Infection Microbiology 7, 452, 2017 | 32 | 2017 |
Transcriptomic analyses implicate neuronal plasticity and chloride homeostasis in ivermectin resistance and response to treatment in a parasitic nematode R Laing, SR Doyle, J McIntyre, K Maitland, A Morrison, DJ Bartley, ... PLoS pathogens 18 (6), e1010545, 2022 | 31 | 2022 |
Analysis of putative resistance gene loci in UK field populations of Haemonchus contortus after 6 years of macrocyclic lactone use R Laing, K Maitland, L Lecová, PJ Skuce, A Tait, E Devaney International journal for parasitology 46 (10), 621-630, 2016 | 31 | 2016 |
Profiling microRNAs through development of the parasitic nematode Haemonchus identifies nematode-specific miRNAs that suppress larval development ND Marks, AD Winter, HY Gu, K Maitland, V Gillan, M Ambroz, A Martinelli, ... Scientific reports 9 (1), 17594, 2019 | 30 | 2019 |