Stebėti
Roz Laing
Roz Laing
Wellcome Clinical Research Career Development Fellow, SBOHVM, University of Glasgow
Patvirtintas el. paštas glasgow.ac.uk
Pavadinimas
Cituota
Cituota
Metai
Ivermectin–old drug, new tricks?
R Laing, V Gillan, E Devaney
Trends in parasitology 33 (6), 463-472, 2017
4912017
The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery
R Laing, T Kikuchi, A Martinelli, IJ Tsai, RN Beech, E Redman, N Holroyd, ...
Genome biology 14, 1-16, 2013
3922013
Refugia and anthelmintic resistance: concepts and challenges
JE Hodgkinson, RM Kaplan, F Kenyon, ER Morgan, AW Park, S Paterson, ...
International Journal for Parasitology: Drugs and Drug Resistance 10, 51-57, 2019
1422019
Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm
SR Doyle, A Tracey, R Laing, N Holroyd, D Bartley, W Bazant, H Beasley, ...
Communications biology 3 (1), 656, 2020
1402020
Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus
SR Doyle, CJR Illingworth, R Laing, DJ Bartley, E Redman, A Martinelli, ...
BMC genomics 20, 1-19, 2019
952019
Characterization of the xenobiotic response of Caenorhabditis elegans to the anthelmintic drug albendazole and the identification of novel drug glucoside metabolites
ST Laing, A Ivens, R Laing, S Ravikumar, V Butler, DJ Woods, JS Gilleard
Biochemical Journal 432 (3), 505-516, 2010
912010
Characterization and comparative analysis of the complete Haemonchus contortus β-tubulin gene family and implications for benzimidazole resistance in strongylid nematodes
GI Saunders, JD Wasmuth, R Beech, R Laing, M Hunt, H Naghra, ...
International journal for parasitology 43 (6), 465-475, 2013
812013
The cytochrome P450 family in the parasitic nematode Haemonchus contortus
R Laing, DJ Bartley, AA Morrison, A Rezansoff, A Martinelli, ST Laing, ...
International journal for parasitology 45 (4), 243-251, 2015
752015
A genome resequencing-based genetic map reveals the recombination landscape of an outbred parasitic nematode in the presence of polyploidy and polyandry
SR Doyle, R Laing, DJ Bartley, C Britton, U Chaudhry, JS Gilleard, ...
Genome Biology and Evolution 10 (2), 396-409, 2018
692018
Genomic landscape of drug response reveals mediators of anthelmintic resistance
SR Doyle, R Laing, D Bartley, A Morrison, N Holroyd, K Maitland, ...
Cell Reports 41 (3), 2022
63*2022
The Transcriptional Response of Caenorhabditis elegans to Ivermectin Exposure Identifies Novel Genes Involved in the Response to Reduced Food Intake
ST Laing, A Ivens, V Butler, SP Ravikumar, R Laing, DJ Woods, ...
PloS one 7 (2), e31367, 2012
552012
UDP-glycosyltransferase family in Haemonchus contortus: phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences
P Matoušková, L Lecová, R Laing, D Dimunová, H Vogel, LR Stuchlíková, ...
International Journal for Parasitology: Drugs and Drug Resistance 8 (3), 420-429, 2018
482018
Evidence from two independent backcross experiments supports genetic linkage of microsatellite Hcms8a20, but not other candidate loci, to a major ivermectin resistance locus in …
AM Rezansoff, R Laing, JS Gilleard
International journal for parasitology 46 (10), 653-661, 2016
452016
Evaluation of DNA extraction methods on individual helminth egg and larval stages for whole-genome sequencing
SR Doyle, G Sankaranarayanan, F Allan, D Berger, PD Jimenez Castro, ...
Frontiers in Genetics 10, 826, 2019
412019
Small RNAs in parasitic nematodes–forms and functions
C Britton, R Laing, E Devaney
Parasitology 147 (8), 855-864, 2020
372020
Haemonchus contortus: genome structure, organization and comparative genomics
R Laing, A Martinelli, A Tracey, N Holroyd, JS Gilleard, JA Cotton
Advances in Parasitology 93, 569-598, 2016
342016
Increased expression of a microRNA correlates with anthelmintic resistance in parasitic nematodes
V Gillan, K Maitland, R Laing, H Gu, ND Marks, AD Winter, D Bartley, ...
Frontiers in Cellular and Infection Microbiology 7, 452, 2017
322017
Transcriptomic analyses implicate neuronal plasticity and chloride homeostasis in ivermectin resistance and response to treatment in a parasitic nematode
R Laing, SR Doyle, J McIntyre, K Maitland, A Morrison, DJ Bartley, ...
PLoS pathogens 18 (6), e1010545, 2022
312022
Analysis of putative resistance gene loci in UK field populations of Haemonchus contortus after 6 years of macrocyclic lactone use
R Laing, K Maitland, L Lecová, PJ Skuce, A Tait, E Devaney
International journal for parasitology 46 (10), 621-630, 2016
312016
Profiling microRNAs through development of the parasitic nematode Haemonchus identifies nematode-specific miRNAs that suppress larval development
ND Marks, AD Winter, HY Gu, K Maitland, V Gillan, M Ambroz, A Martinelli, ...
Scientific reports 9 (1), 17594, 2019
302019
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