| Cell type–specific delivery of siRNAs with aptamer-siRNA chimeras JO McNamara, ER Andrechek, Y Wang, KD Viles, RE Rempel, E Gilboa, ... Nature biotechnology 24 (8), 1005-1015, 2006 | 1305 | 2006 |
| The E2F1–3 transcription factors are essential for cellular proliferation L Wu, C Timmers, B Maiti, HI Saavedra, L Sang, GT Chong, F Nuckolls, ... Nature 414 (6862), 457-462, 2001 | 779 | 2001 |
| Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors JP Dassie, X Liu, GS Thomas, RM Whitaker, KW Thiel, KR Stockdale, ... Nature biotechnology 27 (9), 839-846, 2009 | 721 | 2009 |
| Cardiovascular transition at birth: a physiological sequence SB Hooper, AB Te Pas, J Lang, JJ van Vonderen, CC Roehr, M Kluckow, ... Pediatric research 77 (5), 608-614, 2015 | 600* | 2015 |
| The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding PH Giangrande, E A. Kimbrel, DP Edwards, DP McDonnell Molecular and cellular biology 20 (9), 3102-3115, 2000 | 450 | 2000 |
| The A and B isoforms of the human progesterone receptor: two functionally different transcription factors encoded by a single gene. PH Giangrande, DP McDonnell Recent progress in hormone research 54, 291-313; discussion 313, 1999 | 427 | 1999 |
| E2Fs link the control of G1/S and G2/M transcription W Zhu, PH Giangrande, JR Nevins The EMBO journal 23 (23), 4615-4626, 2004 | 394 | 2004 |
| Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice JO McNamara, D Kolonias, F Pastor, RS Mittler, L Chen, PH Giangrande, ... The Journal of clinical investigation 118 (1), 376-386, 2008 | 368 | 2008 |
| Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay F Pastor, D Kolonias, PH Giangrande, E Gilboa Nature 465 (7295), 227-230, 2010 | 340 | 2010 |
| Myc requires distinct E2F activities to induce S phase and apoptosis G Leone, R Sears, E Huang, R Rempel, F Nuckolls, CH Park, ... Molecular cell 8 (1), 105-113, 2001 | 335 | 2001 |
| Reduction of chromium (VI) by ascorbate leads to chromium-DNA binding and DNA strand breaks in vitro DM Stearns, LJ Kennedy, KD Courtney, PH Giangrande, LS Phieffer, ... Biochemistry 34 (3), 910-919, 1995 | 287 | 1995 |
| Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers KW Thiel, LI Hernandez, JP Dassie, WH Thiel, X Liu, KR Stockdale, ... Nucleic acids research 40 (13), 6319-6337, 2012 | 256 | 2012 |
| Mapping and characterization of the functional domains responsible for the differential activity of the A and B isoforms of the human progesterone receptor PH Giangrande, G Pollio, DP McDonnell Journal of Biological Chemistry 272 (52), 32889-32900, 1997 | 245 | 1997 |
| Therapeutic applications of DNA and RNA aptamers KW Thiel, PH Giangrande Oligonucleotides 19 (3), 209-222, 2009 | 213 | 2009 |
| Hormone-Dependent Interaction between the Amino- and Carboxyl-Terminal Domains of Progesterone Receptor in Vitro and in Vivo MJ Tetel, PH Giangrande, SA Leonhardt, DP McDonnell, DP Edwards Molecular endocrinology 13 (6), 910-924, 1999 | 206 | 1999 |
| Multifunctional aptamer-miRNA conjugates for targeted cancer therapy CL Esposito, L Cerchia, S Catuogno, G De Vita, JP Dassie, G Santamaria, ... Molecular therapy 22 (6), 1151-1163, 2014 | 186 | 2014 |
| Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling WM Rockey, FJ Hernandez, SY Huang, S Cao, CA Howell, GS Thomas, ... Nucleic acid therapeutics 21 (5), 299-314, 2011 | 158 | 2011 |
| Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection WH Thiel, T Bair, AS Peek, X Liu, J Dassie, KR Stockdale, MA Behlke, ... Public Library of Science 7 (9), e43836, 2012 | 146 | 2012 |
| A role for E2F6 in distinguishing G1/S-and G2/M-specific transcription PH Giangrande, W Zhu, S Schlisio, X Sun, S Mori, S Gaubatz, JR Nevins Genes & development 18 (23), 2941-2951, 2004 | 141 | 2004 |
| Isolation and optimization of murine IL-10 receptor blocking oligonucleotide aptamers using high-throughput sequencing A Berezhnoy, CA Stewart, JO Mcnamara II, W Thiel, P Giangrande, ... Molecular Therapy 20 (6), 1242-1250, 2012 | 138 | 2012 |
