In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation PCJ Armstrong, PD Leadbeater, MV Chan, NS Kirkby, JA Jakubowski, ... Journal of Thrombosis and Haemostasis 9 (3), 552-561, 2011 | 208 | 2011 |
Association of microRNAs and YRNAs with platelet function D Kaudewitz, P Skroblin, LH Bender, T Barwari, P Willeit, R Pechlaner, ... Circulation research 118 (3), 420-432, 2016 | 203 | 2016 |
Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways NS Kirkby, MV Chan, AK Zaiss, E Garcia-Vaz, J Jiao, LM Berglund, ... Proceedings of the National Academy of Sciences 113 (2), 434-439, 2016 | 203 | 2016 |
Anti-inflammatory and cytoprotective actions of hydrogen sulfide: translation to therapeutics JL Wallace, RW Blackler, MV Chan, GJ Da Silva, W Elsheikh, ... Antioxidants & redox signaling 22 (5), 398-410, 2015 | 177 | 2015 |
Hydrogen sulfide-based therapeutics and gastrointestinal diseases: translating physiology to treatments MV Chan, JL Wallace American Journal of Physiology-Gastrointestinal and Liver Physiology 305 (7 …, 2013 | 133 | 2013 |
Antiplatelet effects of aspirin vary with level of P2Y12 receptor blockade supplied by either ticagrelor or prasugrel NS Kirkby, PDM Leadbeater, MV Chan, S Nylander, JA Mitchell, ... Journal of Thrombosis and Haemostasis 9 (10), 2103-2105, 2011 | 85 | 2011 |
Eicosanoids in platelets and the effect of their modulation by aspirin in the cardiovascular system (and beyond) M Crescente, L Menke, MV Chan, PC Armstrong, TD Warner British journal of pharmacology 176 (8), 988-999, 2019 | 82 | 2019 |
Newly formed reticulated platelets undermine pharmacokinetically short-lived antiplatelet therapies PC Armstrong, T Hoefer, RB Knowles, AT Tucker, MA Hayman, ... Arteriosclerosis, thrombosis, and vascular biology 37 (5), 949-956, 2017 | 80 | 2017 |
Optical multichannel (optimul) platelet aggregometry in 96-well plates as an additional method of platelet reactivity testing MV Chan, PCJ Armstrong, F Papalia, NS Kirkby, TD Warner Platelets 22 (7), 485-494, 2011 | 78 | 2011 |
Characterization of multiple platelet activation pathways in patients with bleeding as a high-throughput screening option: use of 96-well Optimul assay M Lordkipanidzé, GC Lowe, NS Kirkby, MV Chan, MH Lundberg, ... Blood, The Journal of the American Society of Hematology 123 (8), e11-e22, 2014 | 74 | 2014 |
Blockade of the purinergic P2Y12 receptor greatly increases the platelet inhibitory actions of nitric oxide NS Kirkby, MH Lundberg, MV Chan, I Vojnovic, AB Solomon, M Emerson, ... Proceedings of the National Academy of Sciences 110 (39), 15782-15787, 2013 | 70 | 2013 |
Differential COX-2 induction by viral and bacterial PAMPs: Consequences for cytokine and interferon responses and implications for anti-viral COX-2 directed therapies NS Kirkby, AK Zaiss, WR Wright, J Jiao, MV Chan, TD Warner, ... Biochemical and biophysical research communications 438 (2), 249-256, 2013 | 56 | 2013 |
Distinct endothelial pathways underlie sexual dimorphism in vascular auto‐regulation MV Chan, KJ Bubb, A Noyce, IC Villar, J Duchene, AJ Hobbs, ... British journal of pharmacology 167 (4), 805-817, 2012 | 50 | 2012 |
96-well plate-based aggregometry MV Chan, PC Armstrong, TD Warner Platelets 29 (7), 650-655, 2018 | 49 | 2018 |
Proteome and functional decline as platelets age in the circulation HE Allan, MA Hayman, S Marcone, MV Chan, ML Edin, T Maffucci, ... Journal of Thrombosis and Haemostasis 19 (12), 3095-3112, 2021 | 47 | 2021 |
Neutrophil-derived protein S100A8/A9 alters the platelet proteome in acute myocardial infarction and is associated with changes in platelet reactivity A Joshi, LE Schmidt, SA Burnap, R Lu, MV Chan, PC Armstrong, F Baig, ... Arteriosclerosis, thrombosis, and vascular biology 42 (1), 49-62, 2022 | 45 | 2022 |
Standardised optical multichannel (optimul) platelet aggregometry using high-speed shaking and fixed time point readings MV Chan, TD Warner Platelets 23 (5), 404-408, 2012 | 44 | 2012 |
A year of COVID-19 GWAS results from the GRASP portal reveals potential genetic risk factors F Thibord, MV Chan, MH Chen, AD Johnson Human Genetics and Genomics Advances 3 (2), 2022 | 43 | 2022 |
P2Y12 receptor blockade synergizes strongly with nitric oxide and prostacyclin to inhibit platelet activation MV Chan, RBM Knowles, MH Lundberg, AT Tucker, NA Mohamed, ... British journal of clinical pharmacology 81 (4), 621-633, 2016 | 43 | 2016 |
Loss of GPVI and GPIbα contributes to trauma-induced platelet dysfunction in severely injured patients P Vulliamy, SJ Montague, S Gillespie, MV Chan, LA Coupland, ... Blood advances 4 (12), 2623-2630, 2020 | 42 | 2020 |