| Luminescent probes for the bioimaging of small anionic species in vitro and in vivo TD Ashton, KA Jolliffe, FM Pfeffer Chemical Society Reviews 44 (14), 4547-4595, 2015 | 371 | 2015 |
| The development process for discovery and clinical advancement of modern antimalarials TD Ashton, SM Devine, JJ Mohrle, B Laleu, JN Burrows, SA Charman, ... Journal of Medicinal Chemistry 62 (23), 10526-10562, 2019 | 85 | 2019 |
| Disruption of the class IIa HDAC corepressor complex increases energy expenditure and lipid oxidation V Gaur, T Connor, A Sanigorski, SD Martin, CR Bruce, DC Henstridge, ... Cell reports 16 (11), 2802-2810, 2016 | 80 | 2016 |
| Synthesis and Characterization of Novel 2-Amino-3-benzoylthiophene Derivatives as Biased Allosteric Agonists and Modulators of the Adenosine A1 Receptor C Valant, L Aurelio, SM Devine, TD Ashton, JM White, PM Sexton, ... Journal of medicinal chemistry 55 (5), 2367-2375, 2012 | 62 | 2012 |
| Pharmacological validation of Trypanosoma brucei phosphodiesterases B1 and B2 as druggable targets for African sleeping sickness ND Bland, C Wang, C Tallman, AE Gustafson, Z Wang, TD Ashton, ... Journal of medicinal chemistry 54 (23), 8188-8194, 2011 | 61 | 2011 |
| In silico identification of an aryl hydrocarbon receptor antagonist with biological activity in vitro and in vivo AJ Parks, MP Pollastri, ME Hahn, EA Stanford, O Novikov, DG Franks, ... Molecular pharmacology 86 (5), 593-608, 2014 | 56 | 2014 |
| Modular synthesis of 4-aminocarbonyl substituted 1, 8-naphthalimides and application in single molecule fluorescence detection KN Hearn, TD Nalder, RP Cox, HD Maynard, TDM Bell, FM Pfeffer, ... Chemical Communications 53 (91), 12298-12301, 2017 | 53 | 2017 |
| Improved synthesis and structural reassignment of MC1568: a class IIa selective HDAC inhibitor CL Fleming, TD Ashton, V Gaur, SL McGee, FM Pfeffer Journal of medicinal chemistry 57 (3), 1132-1135, 2014 | 53 | 2014 |
| An Improved Process for the N‐Demethylation of Opiate Alkaloids using an Iron (II) Catalyst in Acetate Buffer G Kok, TD Ashton, PJ Scammells Advanced Synthesis & Catalysis 351 (1‐2), 283-286, 2009 | 53 | 2009 |
| Blue Electrogenerated Chemiluminescence from Water‐Soluble Iridium Complexes Containing Sulfonated Phenylpyridine or Tetraethylene Glycol Derivatized Triazolylpyridine Ligands E Kerr, EH Doeven, GJ Barbante, TU Connell, PS Donnelly, DJD Wilson, ... Chemistry–A European Journal 21 (42), 14987-14995, 2015 | 50 | 2015 |
| Structure–activity relationships of adenosines with heterocyclic N6-substituents TD Ashton, KM Aumann, SP Baker, CH Schiesser, PJ Scammells Bioorganic & medicinal chemistry letters 17 (24), 6779-6784, 2007 | 50 | 2007 |
| Identification and Characterization of Kava‐derived Compounds Mediating TNF‐α Suppression MP Pollastri, A Whitty, JC Merrill, X Tang, TD Ashton, S Amar Chemical biology & drug design 74 (2), 121-128, 2009 | 48 | 2009 |
| A fluorescent histone deacetylase (HDAC) inhibitor for cellular imaging CL Fleming, TD Ashton, C Nowell, M Devlin, A Natoli, J Schreuders, ... Chemical Communications 51 (37), 7827-7830, 2015 | 43 | 2015 |
| Norbornane-based cationic antimicrobial peptidomimetics targeting the bacterial membrane SM Hickey, TD Ashton, G Boer, CA Bader, M Thomas, AG Elliott, ... European journal of medicinal chemistry 160, 9-22, 2018 | 35 | 2018 |
| Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 1. Sildenafil analogs C Wang, TD Ashton, A Gustafson, ND Bland, SO Ochiana, RK Campbell, ... Bioorganic & medicinal chemistry letters 22 (7), 2579-2581, 2012 | 32 | 2012 |
| An improved synthesis of 5′-fluoro-5′-deoxyadenosines TD Ashton, PJ Scammells Bioorganic & medicinal chemistry letters 15 (14), 3361-3363, 2005 | 32 | 2005 |
| N6-substituted C5′-modified adenosines as A1 adenosine receptor agonists TD Ashton, SP Baker, SA Hutchinson, PJ Scammells Bioorganic & medicinal chemistry 16 (4), 1861-1873, 2008 | 27 | 2008 |
| Highly fluorescent and HDAC6 selective scriptaid analogues CL Fleming, A Natoli, J Schreuders, M Devlin, P Yoganantharajah, ... European Journal of Medicinal Chemistry 162, 321-333, 2019 | 26 | 2019 |
| Synthesis of norbornane bisether antibiotics via silver-mediated alkylation SM Hickey, TD Ashton, JM White, J Li, RL Nation, YY Heidi, AG Elliott, ... RSC advances 5 (36), 28582-28596, 2015 | 26 | 2015 |
| Microwave-assisted direct amination: Rapid access to multi-functionalized N6-substituted adenosines TD Ashton, PJ Scammells Australian Journal of Chemistry 61 (1), 49-58, 2008 | 25 | 2008 |
