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hui yang
hui yang
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Geverifieerd e-mailadres voor simm.ac.cn
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One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
H Wang, H Yang, CS Shivalila, MM Dawlaty, AW Cheng, F Zhang, ...
cell 153 (4), 910-918, 2013
44532013
One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering
H Yang, H Wang, CS Shivalila, AW Cheng, L Shi, R Jaenisch
Cell 154 (6), 1370-1379, 2013
19982013
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
TP Gu, F Guo, H Yang, HP Wu, GF Xu, W Liu, ZG Xie, L Shi, X He, S Jin, ...
Nature 477 (7366), 606-610, 2011
13432011
Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system
AW Cheng, H Wang, H Yang, L Shi, Y Katz, TW Theunissen, ...
Cell research 23 (10), 1163-1171, 2013
10122013
Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos
E Zuo, Y Sun, W Wei, T Yuan, W Ying, H Sun, L Yuan, LM Steinmetz, Y Li, ...
Science 364 (6437), 289-292, 2019
7872019
Generating genetically modified mice using CRISPR/Cas-mediated genome engineering
H Yang, H Wang, R Jaenisch
Nature protocols 9 (8), 1956-1968, 2014
6212014
Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis
C Zhou, Y Sun, R Yan, Y Liu, E Zuo, C Gu, L Han, Y Wei, X Hu, R Zeng, ...
Nature 571 (7764), 275-278, 2019
4652019
Glia-to-neuron conversion by CRISPR-CasRx alleviates symptoms of neurological disease in mice
H Zhou, J Su, X Hu, C Zhou, H Li, Z Chen, Q Xiao, BO Wang, W Wu, ...
Cell 181 (3), 590-603. e16, 2020
3962020
Homology-mediated end joining-based targeted integration using CRISPR/Cas9
X Yao, X Wang, X Hu, Z Liu, J Liu, H Zhou, X Shen, Y Wei, Z Huang, ...
Cell research 27 (6), 801-814, 2017
3362017
In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9-activator transgenic mice
H Zhou, J Liu, C Zhou, N Gao, Z Rao, H Li, X Hu, C Li, X Yao, X Shen, ...
Nature neuroscience 21 (3), 440-446, 2018
2882018
Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes
C Xu, Y Zhou, Q Xiao, B He, G Geng, Z Wang, B Cao, X Dong, W Bai, ...
Nature methods 18 (5), 499-506, 2021
2682021
Generation of genetically modified mice by oocyte injection of androgenetic haploid embryonic stem cells
H Yang, L Shi, BA Wang, D Liang, C Zhong, W Liu, Y Nie, J Liu, J Zhao, ...
Cell 149 (3), 605-617, 2012
2452012
One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs
E Zuo, YJ Cai, K Li, Y Wei, BA Wang, Y Sun, Z Liu, J Liu, X Hu, W Wei, ...
Cell research 27 (7), 933-945, 2017
2212017
CRISPR/Cas9-mediated targeted chromosome elimination
E Zuo, X Huo, X Yao, X Hu, Y Sun, J Yin, B He, X Wang, L Shi, J Ping, ...
Genome biology 18, 1-18, 2017
2072017
Zscan4 promotes genomic stability during reprogramming and dramatically improves the quality of iPS cells as demonstrated by tetraploid complementation
J Jiang, W Lv, X Ye, L Wang, M Zhang, H Yang, M Okuka, C Zhou, ...
Cell research 23 (1), 92-106, 2013
1702013
Tild-CRISPR allows for efficient and precise gene knockin in mouse and human cells
X Yao, M Zhang, X Wang, W Ying, X Hu, P Dai, F Meng, L Shi, Y Sun, ...
Developmental cell 45 (4), 526-536. e5, 2018
1502018
Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes
H Yang, Z Liu, Y Ma, C Zhong, Q Yin, C Zhou, L Shi, Y Cai, H Zhao, ...
Cell research 23 (10), 1187-1200, 2013
1462013
High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects
H Tong, J Huang, Q Xiao, B He, X Dong, Y Liu, X Yang, D Han, Z Wang, ...
Nature biotechnology 41 (1), 108-119, 2023
1452023
Lentiviral delivery of co-packaged Cas9 mRNA and a Vegfa-targeting guide RNA prevents wet age-related macular degeneration in mice
S Ling, S Yang, X Hu, D Yin, Y Dai, X Qian, D Wang, X Pan, J Hong, ...
Nature biomedical engineering 5 (2), 144-156, 2021
1452021
A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects
E Zuo, Y Sun, T Yuan, B He, C Zhou, W Ying, J Liu, W Wei, R Zeng, Y Li, ...
Nature methods 17 (6), 600-604, 2020
1332020
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