Essential role of Plzf in maintenance of spermatogonial stem cells JA Costoya, RM Hobbs, M Barna, G Cattoretti, K Manova, M Sukhwani, ... Nature genetics 36 (6), 653-659, 2004 | 1103 | 2004 |
The BTB–zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions D Kovalovsky, OU Uche, S Eladad, RM Hobbs, W Yi, E Alonzo, K Chua, ... Nature immunology 9 (9), 1055-1064, 2008 | 651 | 2008 |
Identification of the miR-106b~25 MicroRNA Cluster as a Proto-Oncogenic PTEN-Targeting Intron That Cooperates with Its Host Gene MCM7 in Transformation L Poliseno, L Salmena, L Riccardi, A Fornari, MS Song, RM Hobbs, ... Science signaling 3 (117), ra29-ra29, 2010 | 551 | 2010 |
Generation of functional multipotent adult stem cells from GPR125+ germline progenitors M Seandel, D James, SV Shmelkov, I Falciatori, J Kim, S Chavala, ... Nature 449 (7160), 346-350, 2007 | 542 | 2007 |
Role of the proto-oncogene Pokemon in cellular transformation and ARF repression T Maeda, RM Hobbs, T Merghoub, I Guernah, A Zelent, C Cordon-Cardo, ... Nature 433 (7023), 278-285, 2005 | 519 | 2005 |
Systemic elevation of PTEN induces a tumor-suppressive metabolic state I Garcia-Cao, MS Song, RM Hobbs, G Laurent, C Giorgi, VCJ De Boer, ... Cell 149 (1), 49-62, 2012 | 453 | 2012 |
A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein JH Schefe, M Menk, J Reinemund, K Effertz, RM Hobbs, PP Pandolfi, ... Circulation research 99 (12), 1355-1366, 2006 | 378 | 2006 |
Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function A Papa, L Wan, M Bonora, L Salmena, MS Song, RM Hobbs, A Lunardi, ... Cell 157 (3), 595-610, 2014 | 320 | 2014 |
TCR-inducible PLZF transcription factor required for innate phenotype of a subset of γδ T cells with restricted TCR diversity T Kreslavsky, AK Savage, R Hobbs, F Gounari, R Bronson, P Pereira, ... Proceedings of the National Academy of Sciences 106 (30), 12453-12458, 2009 | 301 | 2009 |
Plzf regulates germline progenitor self-renewal by opposing mTORC1 RM Hobbs, M Seandel, I Falciatori, S Rafii, PP Pandolfi Cell 142 (3), 468-479, 2010 | 290 | 2010 |
Characterization, cryopreservation, and ablation of spermatogonial stem cells in adult rhesus macaques BP Hermann, M Sukhwani, CC Lin, Y Sheng, J Tomko, M Rodriguez, ... Stem cells 25 (9), 2330-2338, 2007 | 268 | 2007 |
Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF T Maeda, T Merghoub, RM Hobbs, L Dong, M Maeda, J Zakrzewski, ... Science 316 (5826), 860-866, 2007 | 251 | 2007 |
Repression of kit expression by Plzf in germ cells D Filipponi, RM Hobbs, S Ottolenghi, P Rossi, EA Jannini, PP Pandolfi, ... Molecular and cellular biology 27 (19), 6770-6781, 2007 | 239 | 2007 |
A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis I Haase, RM Hobbs, MR Romero, S Broad, FM Watt The Journal of clinical investigation 108 (4), 527-536, 2001 | 210 | 2001 |
Functional antagonism between Sall4 and Plzf defines germline progenitors RM Hobbs, S Fagoonee, A Papa, K Webster, F Altruda, R Nishinakamura, ... Cell stem cell 10 (3), 284-298, 2012 | 206 | 2012 |
Development of promyelocytic zinc finger and ThPOK-expressing innate γδ T cells is controlled by strength of TCR signaling and Id3 ES Alonzo, RA Gottschalk, J Das, T Egawa, RM Hobbs, PP Pandolfi, ... The journal of immunology 184 (3), 1268-1279, 2010 | 174 | 2010 |
The transcription factor Pokemon: a new key player in cancer pathogenesis T Maeda, RM Hobbs, PP Pandolfi Cancer research 65 (19), 8575-8578, 2005 | 174 | 2005 |
LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis T Maeda, K Ito, T Merghoub, L Poliseno, RM Hobbs, G Wang, L Dong, ... Developmental cell 17 (4), 527-540, 2009 | 149 | 2009 |
Expression of activated MEK1 in differentiating epidermal cells is sufficient to generate hyperproliferative and inflammatory skin lesions RM Hobbs, V Silva-Vargas, R Groves, FM Watt Journal of investigative dermatology 123 (3), 503-515, 2004 | 121 | 2004 |
Molecular regulation of spermatogonial stem cell renewal and differentiation JA Mäkelä, RM Hobbs Reproduction 158 (5), R169-R187, 2019 | 117 | 2019 |