Large deletions induced by Cas9 cleavage F Adikusuma, S Piltz, MA Corbett, M Turvey, SR McColl, KJ Helbig, ... Nature 560 (7717), E8-E9, 2018 | 370 | 2018 |
Viperin is an important host restriction factor in control of Zika virus infection KH Van der Hoek, NS Eyre, B Shue, O Khantisitthiporn, K Glab-Ampi, ... Scientific reports 7 (1), 4475, 2017 | 125 | 2017 |
Targeted deletion of an entire chromosome using CRISPR/Cas9 F Adikusuma, N Williams, F Grutzner, J Hughes, P Thomas Molecular Therapy 25 (8), 1736-1738, 2017 | 104 | 2017 |
Optimized nickase- and nuclease-based prime editing in human and mouse cells F Adikusuma, C Lushington, J Arudkumar, GI Godahewa, YCJ Chey, ... Nucleic Acids Research 49 (18), 10785–10795, 2021 | 74 | 2021 |
Versatile single-step-assembly CRISPR/Cas9 vectors for dual gRNA expression F Adikusuma, C Pfitzner, PQ Thomas PLoS One 12 (12), e0187236, 2017 | 54 | 2017 |
A Y-chromosome shredding gene drive for controlling pest vertebrate populations TAA Prowse*, F Adikusuma*, P Cassey, P Thomas, JV Ross Elife 8, e41873, 2019 | 52 | 2019 |
Functional equivalence of the SOX2 and SOX3 transcription factors in the developing mouse brain and testes F Adikusuma, D Pederick, D McAninch, J Hughes, P Thomas Genetics 206 (3), 1495-1503, 2017 | 37 | 2017 |
Antisense oligonucleotide therapy for KCNT1 encephalopathy LE Burbano, M Li, N Jancovski, P Jafar-Nejad, K Richards, A Sedo, ... JCI insight 7 (23), 2022 | 35 | 2022 |
Progress toward zygotic and germline gene drives in mice C Pfitzner, MA White, SG Piltz, M Scherer, F Adikusuma, JN Hughes, ... The CRISPR Journal 3 (5), 388-397, 2020 | 32 | 2020 |
CRISPR applications for Duchenne muscular dystrophy: from animal models to potential therapies YCJ Chey, J Arudkumar, A Aartsma‐Rus, F Adikusuma*, PQ Thomas* WIREs Mechanisms of Disease 15 (1), e1580, 2023 | 15 | 2023 |
Expanding the RNA-Guided Endonuclease Toolkit for Mouse Genome Editing L Robertson, D Pederick, S Piltz, M White, A Nieto, M Ahladas, ... The CRISPR Journal 1 (6), 431-439, 2018 | 11 | 2018 |
The Nestin neural enhancer is essential for normal levels of endogenous Nestin in neuroprogenitors but is not required for embryo development E Thomson, R Dawson, CH H’ng, F Adikusuma, S Piltz, PQ Thomas PloS one 16 (11), e0258538, 2021 | 3 | 2021 |
CRISPR-mediated megabase-scale transgene de-duplication to generate a functional single-copy full-length humanized DMD mouse model YCJ Chey, MA Corbett, J Arudkumar, SG Piltz, PQ Thomas, F Adikusuma BMC biology 22 (1), 214, 2024 | 2 | 2024 |
Enhancing gRNA Transcript levels by Reducing the Scaffold Poly-T Tract for Optimal SpCas9-and SaCas9-mediated Gene Editing YCJ Chey, L Gierus, C Lushington, JC Arudkumar, A Geiger, LG Staker, ... bioRxiv, 2024.07. 19.604224, 2024 | 1 | 2024 |
Optimal SpCas9-and SaCas9-mediated gene editing by enhancing gRNA transcript levels through scaffold poly-T tract reduction YCJ Chey, L Gierus, C Lushington, JC Arudkumar, AB Geiger, LG Staker, ... BMC genomics 26, 138, 2025 | | 2025 |
Genetically edited human placental organoids cast new light on the role of ACE2 AL Arthurs, B Dietrich, M Knöfler, CJ Lushington, PQ Thomas, ... Cell Death & Disease 16 (1), 78, 2025 | | 2025 |
CRISPR-mediated generation and comprehensive phenotyping of Duchenne Muscular Dystrophy mouse models J Arudkumar, YCJ Chey, SG Piltz, PQ Thomas, F Adikusuma BMC Methods 1 (1), 1-13, 2024 | | 2024 |
Generation and characterisation of mouse models of Duchenne Muscular Dystrophy (DMD) J Arudkumar, YCJ Chey, SG Piltz, PQ Thomas, F Adikusuma bioRxiv, 2024.08. 11.607106, 2024 | | 2024 |
Megabase-scale Transgene De-Duplication to Generate a Functional Single-Copy Full-Length Humanized DMD Mouse Model YCJ Chey, MA Corbett, J Arudkumar, SG Piltz, PQ Thomas, F Adikusuma bioRxiv, 2024.03. 25.586713, 2024 | | 2024 |
Agent for treating or preventing a dominantly-inherited disease PQ THOMAS, F ADIKUSUMA, AB GEIGER | | 2024 |