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Francesca Mattiroli
Francesca Mattiroli
Group Leader, Hubrecht Institute, Utrecht, the Netherlands
Geverifieerd e-mailadres voor hubrecht.eu
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RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
F Mattiroli, JHA Vissers, WJ van Dijk, P Ikpa, E Citterio, W Vermeulen, ...
Cell 150 (6), 1182-1195, 2012
7452012
RNF8‐and RNF168‐dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
FA Mallette, F Mattiroli, G Cui, LC Young, MJ Hendzel, G Mer, TK Sixma, ...
The EMBO journal 31 (8), 1865-1878, 2012
3982012
Structure of histone-based chromatin in Archaea
F Mattiroli, S Bhattacharyya, PN Dyer, AE White, K Sandman, BW Burkhart, ...
Science 357 (6351), 609-612, 2017
2012017
Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways
F Mattiroli, TK Sixma
Nature structural & molecular biology 21 (4), 308-316, 2014
1792014
Histone ubiquitination: an integrative signaling platform in genome stability
F Mattiroli, L Penengo
Trends in Genetics 37 (6), 566-581, 2021
1662021
Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer
K Nacerddine, JB Beaudry, V Ginjala, B Westerman, F Mattiroli, JY Song, ...
The Journal of clinical investigation 122 (5), 1920-1932, 2012
1422012
The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A
F Mattiroli, M Uckelmann, DD Sahtoe, WJ Van Dijk, TK Sixma
Nature communications 5 (1), 3291, 2014
1072014
DNA-mediated association of two histone-bound complexes of yeast Chromatin Assembly Factor-1 (CAF-1) drives tetrasome assembly in the wake of DNA replication
F Mattiroli, Y Gu, T Yadav, JL Balsbaugh, MR Harris, ES Findlay, Y Liu, ...
Elife 6, e22799, 2017
862017
The right place at the right time: chaperoning core histone variants
F Mattiroli, S D'Arcy, K Luger
EMBO reports 16 (11), 1454-1466, 2015
832015
Mechanistic insights into histone deposition and nucleosome assembly by the chromatin assembly factor-1
PV Sauer, Y Gu, WH Liu, F Mattiroli, D Panne, K Luger, MEA Churchill
Nucleic acids research 46 (19), 9907-9917, 2018
802018
A novel SUMO1-specific interacting motif in dipeptidyl peptidase 9 (DPP9) that is important for enzymatic regulation
E Pilla, U Möller, G Sauer, F Mattiroli, F Melchior, R Geiss-Friedlander
Journal of Biological Chemistry 287 (53), 44320-44329, 2012
722012
In vitro chromatin assembly: strategies and quality control
U Muthurajan, F Mattiroli, S Bergeron, K Zhou, Y Gu, S Chakravarthy, ...
Methods in enzymology 573, 3-41, 2016
532016
The crucial step in ether phospholipid biosynthesis: structural basis of a noncanonical reaction associated with a peroxisomal disorder
A Razeto, F Mattiroli, E Carpanelli, A Aliverti, V Pandini, A Coda, A Mattevi
Structure 15 (6), 683-692, 2007
502007
The Cac2 subunit is essential for productive histone binding and nucleosome assembly in CAF-1
F Mattiroli, Y Gu, JL Balsbaugh, NG Ahn, K Luger
Scientific reports 7 (1), 46274, 2017
302017
Structural aspects of multi-domain RING/Ubox E3 ligases in DNA repair
RG Hibbert, F Mattiroli, TK Sixma
DNA repair 8 (4), 525-535, 2009
292009
CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands
C Rouillon, BV Eckhardt, L Kollenstart, F Gruss, AEE Verkennis, I Rondeel, ...
Nucleic acids research 51 (8), 3770-3792, 2023
242023
Archaeal DNA on the histone merry‐go‐round
S Bhattacharyya, F Mattiroli, K Luger
The FEBS journal 285 (17), 3168-3174, 2018
182018
Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF
I Corbeski, X Guo, BV Eckhardt, D Fasci, W Wiegant, MA Graewert, ...
Science advances 8 (30), eabo0517, 2022
172022
The fork protection complex promotes parental histone recycling and epigenetic memory
SJ Charlton, V Flury, Y Kanoh, AV Genzor, L Kollenstart, W Ao, P Brøgger, ...
Cell 187 (18), 5029-5047. e21, 2024
162024
A public–private partnership model for COVID-19 diagnostics
PHL Krijger, TA Hoek, S Boersma, LIPM Donders, MMC Broeders, ...
Nature biotechnology 39 (10), 1182-1184, 2021
132021
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