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Mark Cookson
Mark Cookson
Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health
Geverifieerd e-mailadres voor mail.nih.gov - Homepage
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
111632021
α-Synuclein locus triplication causes Parkinson's disease
AB Singleton, M Farrer, J Johnson, A Singleton, S Hague, J Kachergus, ...
science 302 (5646), 841-841, 2003
53682003
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
DP Narendra, SM Jin, A Tanaka, DF Suen, CA Gautier, J Shen, ...
PLoS biology 8 (1), e1000298, 2010
31582010
Genome-wide association study reveals genetic risk underlying Parkinson's disease
J Simón-Sánchez, C Schulte, JM Bras, M Sharma, JR Gibbs, D Berg, ...
Nature genetics 41 (12), 1308-1312, 2009
22622009
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
MA Nalls, C Blauwendraat, CL Vallerga, K Heilbron, S Bandres-Ciga, ...
The Lancet Neurology 18 (12), 1091-1102, 2019
19742019
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
RM Canet-Avilés, MA Wilson, DW Miller, R Ahmad, C McLendon, ...
Proceedings of the National Academy of Sciences 101 (24), 9103-9108, 2004
14112004
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain
JR Gibbs, MP Van Der Brug, DG Hernandez, BJ Traynor, MA Nalls, SL Lai, ...
PLoS genetics 6 (5), e1000952, 2010
9162010
Common genetic variants influence human subcortical brain structures
DP Hibar, JL Stein, ME Renteria, A Arias-Vasquez, S Desrivières, ...
Nature 520 (7546), 224-229, 2015
8992015
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
E Greggio, S Jain, A Kingsbury, R Bandopadhyay, P Lewis, A Kaganovich, ...
Neurobiology of disease 23 (2), 329-341, 2006
8632006
The biochemistry of Parkinson's disease
MR Cookson
Annu. Rev. Biochem. 74 (1), 29-52, 2005
8432005
Hallmarks of neurodegenerative diseases
DM Wilson, MR Cookson, L Van Den Bosch, H Zetterberg, DM Holtzman, ...
Cell 186 (4), 693-714, 2023
7782023
An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered α-synuclein metabolism and oxidative damage
TB Sherer, R Betarbet, AK Stout, S Lund, M Baptista, AV Panov, ...
Journal of Neuroscience 22 (16), 7006-7015, 2002
7512002
Genetic variability in the regulation of gene expression in ten regions of the human brain
A Ramasamy, D Trabzuni, S Guelfi, V Varghese, C Smith, R Walker, T De, ...
Nature neuroscience 17 (10), 1418-1428, 2014
7232014
Parkin protects against the toxicity associated with mutant α-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons
L Petrucelli, C O'Farrell, PJ Lockhart, M Baptista, K Kehoe, L Vink, P Choi, ...
Neuron 36 (6), 1007-1019, 2002
7232002
α‐Synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma
OMA El-Agnaf, SA Salem, KE Paleologou, LJ Cooper, NJ Fullwood, ...
The FASEB Journal 17 (13), 1-16, 2003
7092003
The transcriptional landscape of age in human peripheral blood
MJ Peters, R Joehanes, LC Pilling, C Schurmann, KN Conneely, J Powell, ...
Nature communications 6 (1), 8570, 2015
6782015
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
GU Höglinger, NM Melhem, DW Dickson, PMA Sleiman, LS Wang, L Klei, ...
Nature genetics 43 (7), 699-705, 2011
6512011
The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease
MR Cookson
Nature Reviews Neuroscience 11 (12), 791-797, 2010
6222010
A soluble α-synuclein construct forms a dynamic tetramer
W Wang, I Perovic, J Chittuluru, A Kaganovich, LTT Nguyen, J Liao, ...
Proceedings of the National Academy of Sciences 108 (43), 17797-17802, 2011
6102011
Evidence for natural antisense transcript-mediated inhibition of microRNA function
MA Faghihi, M Zhang, J Huang, F Modarresi, MP Van der Brug, MA Nalls, ...
Genome biology 11, 1-13, 2010
6082010
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Artikelen 1–20