| Comprehensive evaluation of the 5XFAD mouse model for preclinical testing applications: a MODEL-AD study AL Oblak, PB Lin, KP Kotredes, RS Pandey, D Garceau, HM Williams, ... Frontiers in aging neuroscience 13, 713726, 2021 | 235 | 2021 |
| INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia AP Tsai, PBC Lin, C Dong, M Moutinho, BT Casali, Y Liu, BT Lamb, ... Neurobiology of disease 153, 105303, 2021 | 90 | 2021 |
| PLCG2 is associated with the inflammatory response and is induced by amyloid plaques in Alzheimer’s disease AP Tsai, C Dong, PBC Lin, EJ Messenger, BT Casali, M Moutinho, Y Liu, ... Genome Medicine 14 (1), 17, 2022 | 73 | 2022 |
| The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer’s disease M Moutinho, SS Puntambekar, AP Tsai, I Coronel, PB Lin, BT Casali, ... Science translational medicine 14 (637), eabl7634, 2022 | 63 | 2022 |
| CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer’s disease SS Puntambekar, M Moutinho, PBC Lin, V Jadhav, D Tumbleson-Brink, ... Molecular neurodegeneration 17 (1), 47, 2022 | 52 | 2022 |
| Deletion of Abi3 gene locus exacerbates neuropathological features of Alzheimer’s disease in a mouse model of Aβ amyloidosis H Karahan, DC Smith, B Kim, LC Dabin, MM Al-Amin, HRS Wijeratne, ... Science Advances 7 (45), eabe3954, 2021 | 44 | 2021 |
| Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice VS Jadhav, PBC Lin, T Pennington, GV Di Prisco, AJ Jannu, G Xu, ... Molecular Neurodegeneration 15, 1-16, 2020 | 40 | 2020 |
| Uncovering disease mechanisms in a novel mouse model expressing humanized APOEε4 and Trem2* R47H KP Kotredes, A Oblak, RS Pandey, PBC Lin, D Garceau, H Williams, ... Frontiers in Aging Neuroscience 13, 735524, 2021 | 37 | 2021 |
| INPP5D deficiency attenuates amyloid pathology in a mouse model of Alzheimer's disease PBC Lin, APY Tsai, D Soni, A Lee‐Gosselin, M Moutinho, ... Alzheimer's & Dementia 19 (6), 2528-2537, 2023 | 33 | 2023 |
| Metabolic defects caused by high-fat diet modify disease risk through inflammatory and amyloidogenic pathways in a mouse model of Alzheimer’s disease AM Reilly, AP Tsai, PB Lin, AC Ericsson, AL Oblak, H Ren Nutrients 12 (10), 2977, 2020 | 31 | 2020 |
| Acute alcohol intoxication aggravates brain injury caused by intracerebral hemorrhage in rats HK Liew, HY Cheng, LC Huang, KW Li, HF Peng, HI Yang, PBC Lin, ... Journal of stroke and cerebrovascular diseases 25 (1), 15-25, 2016 | 26 | 2016 |
| Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer’s disease AP Tsai, C Dong, PBC Lin, AL Oblak, GV Di Prisco, N Wang, N Hajicek, ... Immunity 56 (9), 2121-2136. e6, 2023 | 22 | 2023 |
| Over-activated proteasome mediates neuroinflammation on acute intracerebral hemorrhage in rats HK Liew, WF Hu, PBC Lin, PK Wang, APY Tsai, CY Pang, TY Chen Cells 8 (11), 1326, 2019 | 20 | 2019 |
| Plcg2M28L Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer’s Disease-Relevant Phenotypes in Mice AL Oblak, KP Kotredes, RS Pandey, AM Reagan, C Ingraham, B Perkins, ... Frontiers in Aging Neuroscience 14, 886575, 2022 | 15 | 2022 |
| PLCG2 as a Risk Factor for Alzheimer’s Disease AP Tsai, C Dong, C Preuss, M Moutinho, PBC Lin, N Hajicek, J Sondek, ... bioRxiv, 2020.05. 19.104216, 2020 | 11 | 2020 |
| The role of urocortins in intracerebral hemorrhage KW Choy, APY Tsai, PBC Lin, MY Wu, C Lee, A Alias, CY Pang, HK Liew Biomolecules 10 (1), 96, 2020 | 10 | 2020 |
| Moderate ethanol pre-treatment mitigates ICH-induced injury via ER stress modulation in rats PBC Lin, PK Wang, CY Pang, WF Hu, APY Tsai, AL Oblak, HK Liew Frontiers in Molecular Neuroscience 14, 682775, 2021 | 8 | 2021 |
| Age-dependent microstructure alterations in 5xFAD mice by high-resolution diffusion tensor imaging S Maharjan, AP Tsai, PB Lin, C Ingraham, MR Jewett, GE Landreth, ... Frontiers in Neuroscience 16, 964654, 2022 | 6 | 2022 |
| Therapeutic potential of niacin in Alzheimer's disease: Nonhuman/Target identification and validation studies: Other M Moutinho, AP Tsai, SS Puntambekar, J Patel, PB Lin, V Jadhav, ... Alzheimer's & Dementia 16, e040679, 2020 | 6 | 2020 |
| Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer’s progression JF Codocedo, C Mera-Reina, PBC Lin, PB Fallen, SS Puntambekar, ... Cell reports 43 (7), 2024 | 4 | 2024 |
Adrian L OblakAssistant Professor, Indiana University School of MedicineGeverifieerd e-mailadres voor IUPUI.EDU
