| Intron retention as a component of regulated gene expression programs AG Jacob, CWJ Smith Human genetics 136 (9), 1043-1057, 2017 | 317 | 2017 |
| Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage DF Comiskey Jr, AG Jacob, RK Singh, AS Tapia-Santos, DS Chandler Nucleic acids research 43 (8), 4202-4218, 2015 | 51 | 2015 |
| The splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA AG Jacob, RK Singh, F Mohammad, TW Bebee, DS Chandler Journal of Biological Chemistry 289 (25), 17350-17364, 2014 | 44 | 2014 |
| Identification of RBPMS as a mammalian smooth muscle master splicing regulator via proximity of its gene with super-enhancers EE Nakagaki-Silva, C Gooding, M Llorian, AG Jacob, F Richards, ... Elife 8, e46327, 2019 | 40 | 2019 |
| Advances in pediatric rhabdomyosarcoma characterization and disease model development D O’Brien, AG Jacob, SJ Qualman, DS Chandler Histology and histopathology 27 (1), 13, 2012 | 39 | 2012 |
| Stress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct ways AG Jacob, RK Singh, DF Comiskey Jr, MF Rouhier, F Mohammad, ... PLoS One 9 (8), e104444, 2014 | 34 | 2014 |
| Stress-induced isoforms of MDM2 and MDM4 correlate with high-grade disease and an altered splicing network in pediatric rhabdomyosarcoma AG Jacob, D O'Brien, RK Singh, DF Comiskey Jr, RM Littleton, ... Neoplasia 15 (9), 1049-IN8, 2013 | 28 | 2013 |
| A novel mouse model of rhabdomyosarcoma underscores the dichotomy of MDM2-ALT1 function in vivo DF Comiskey Jr, AG Jacob, BL Sanford, M Montes, AK Goodwin, ... Oncogene 37 (1), 95-106, 2018 | 14 | 2018 |
| Myocardin regulates exon usage in smooth muscle cells through induction of splicing regulatory factors L Liu, D Kryvokhyzha, C Rippe, A Jacob, A Borreguero-Muñoz, ... Cellular and Molecular Life Sciences 79 (8), 459, 2022 | 12 | 2022 |
| Densified collagen tubular grafts for human tissue replacement and disease modelling applications AW Justin, F Cammarata, AA Guy, SR Estevez, S Burgess, H Davaapil, ... Biomaterials Advances 145, 213245, 2023 | 5 | 2023 |
| RBPMS promotes contractile smooth muscle splicing and alters phenotypic behaviour of human embryonic stem cell derived vascular smooth muscle cells AG Jacob, I Moutsopoulous, A Petchey, I Mohorianu, S Sinha, CWJ Smith BiorXiv, 2022.11. 27.516868, 2022 | 2 | 2022 |
| Understanding genomic medicine for thoracic aortic disease through the lens of induced pluripotent stem cells AA Singh, DK Shetty, AG Jacob, S Bayraktar, S Sinha Frontiers in cardiovascular medicine 11, 1349548, 2024 | 1 | 2024 |
| Differentiation and quality control of smooth muscle cells from human pluripotent stem cells via the neural crest lineage PJ Holt, H Davaapil, DK Shetty, AG Jacob, S Sinha bioRxiv, 2023.05. 31.543049, 2023 | 1 | 2023 |
| Identification of RBPMS as a smooth muscle master splicing regulator via proximity of its gene with super-enhancers EE Nakagaki-Silva, C Gooding, M Llorian, AG Jacob, F Richards, ... bioRxiv, 563304, 2019 | 1 | 2019 |
| RNA binding protein with multiple splicing (RBPMS) promotes contractile phenotype splicing in human embryonic stem cell–derived vascular smooth muscle cells AG Jacob, I Moutsopoulos, A Petchey, R Kollyfas, VR Knight-Schrijver, ... Cardiovascular Research 120 (16), 2104-2116, 2024 | | 2024 |
| RBPMS promotes contractile phenotype splicing in human embryonic stem cell derived vascular smooth muscle cells. A Jacob, I Moutsopoulous, A Petchey, R Kollyfas, VR Knight-Schrijver, ... European Society of Cardiology, 2024 | | 2024 |
| BS52 RNA binding protein multiple splicing (RBPMS) drives a contractile splicing network in human embryonic stem cell derived vascular smooth muscle cells. A Jacob, I Moutsopoulous, A Petchey, I Mohorianu, C Smith, S Sinha Heart 109 (Suppl 3), A281-A282, 2023 | | 2023 |
| BS17 RNA binding protein multiple splicing (RBPMS) drives a contractile splicing network in human embryonic stem cell derived vascular smooth muscle cells A Jacob, S Sinha, C Smith Heart 107 (Suppl 1), A164-A166, 2021 | | 2021 |
| The dual role of MDM2-ALT1 as both a suppressor and driver of oncogenesis is highlighted in a new RMS mouse model DF Comiskey, AG Jacob, M Montes, KL Perle, PN Boyaka, DS Chandler Cancer Research 78 (13_Supplement), 4140-4140, 2018 | | 2018 |
