Antisense RNA stabilization induces transcriptional gene silencing via histone deacetylation in S. cerevisiae J Camblong, N Iglesias, C Fickentscher, G Dieppois, F Stutz Cell 131 (4), 706-717, 2007 | 421 | 2007 |
The Rat1p 5′ to 3′ exonuclease degrades telomeric repeat-containing RNA and promotes telomere elongation in Saccharomyces cerevisiae B Luke, A Panza, S Redon, N Iglesias, Z Li, J Lingner Molecular cell 32 (4), 465-477, 2008 | 415 | 2008 |
Cotranscriptional recruitment to the mRNA export receptor Mex67p contributes to nuclear pore anchoring of activated genes G Dieppois, N Iglesias, F Stutz Molecular and cellular biology 26 (21), 7858-7870, 2006 | 216 | 2006 |
TERRA biogenesis, turnover and implications for function S Feuerhahn, N Iglesias, A Panza, A Porro, J Lingner FEBS letters 584 (17), 3812-3818, 2010 | 205 | 2010 |
Ubiquitin-mediated mRNP dynamics and surveillance prior to budding yeast mRNA export N Iglesias, E Tutucci, C Gwizdek, P Vinciguerra, E Von Dach, AH Corbett, ... Genes & development 24 (17), 1927-1938, 2010 | 177 | 2010 |
Perinuclear Mlp proteins downregulate gene expression in response to a defect in mRNA export P Vinciguerra, N Iglesias, J Camblong, D Zenklusen, F Stutz The EMBO journal 24 (4), 813-823, 2005 | 163 | 2005 |
Ubiquitin-associated domain of Mex67 synchronizes recruitment of the mRNA export machinery with transcription C Gwizdek, N Iglesias, MS Rodriguez, B Ossareh-Nazari, M Hobeika, ... Proceedings of the National Academy of Sciences 103 (44), 16376-16381, 2006 | 158 | 2006 |
Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription G Jih, N Iglesias, MA Currie, NV Bhanu, JA Paulo, SP Gygi, BA Garcia, ... Nature 547 (7664), 463-467, 2017 | 140 | 2017 |
Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast N Iglesias, S Redon, V Pfeiffer, M Dees, J Lingner, B Luke EMBO reports 12 (6), 587-593, 2011 | 138 | 2011 |
Regulation of mRNP dynamics along the export pathway N Iglesias, F Stutz FEBS letters 582 (14), 1987-1996, 2008 | 113 | 2008 |
Native chromatin proteomics reveals a role for specific nucleoporins in heterochromatin organization and maintenance N Iglesias, JA Paulo, A Tatarakis, X Wang, AL Edwards, NV Bhanu, ... Molecular cell 77 (1), 51-66. e8, 2020 | 95 | 2020 |
Determinants of heterochromatic siRNA biogenesis and function R Yu, G Jih, N Iglesias, D Moazed Molecular cell 53 (2), 262-276, 2014 | 72 | 2014 |
Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability N Iglesias, MA Currie, G Jih, JA Paulo, N Siuti, M Kalocsay, SP Gygi, ... Nature 560 (7719), 504-508, 2018 | 70 | 2018 |
Structural basis for polyadenosine-RNA binding by Nab2 Zn fingers and its function in mRNA nuclear export C Brockmann, S Soucek, SI Kuhlmann, K Mills-Lujan, SM Kelly, JC Yang, ... Structure 20 (6), 1007-1018, 2012 | 43 | 2012 |
Coordination of Hpr1 and ubiquitin binding by the UBA domain of the mRNA export factor Mex67 M Hobeika, C Brockmann, N Iglesias, C Gwizdek, D Neuhaus, F Stutz, ... Molecular biology of the cell 18 (7), 2561-2568, 2007 | 39 | 2007 |
Heterochromatin assembly by interrupted Sir3 bridges across neighboring nucleosomes R Behrouzi, C Lu, MA Currie, G Jih, N Iglesias, D Moazed Elife 5, e17556, 2016 | 35 | 2016 |
Distinct functions of argonaute slicer in siRNA maturation and heterochromatin formation R Jain, N Iglesias, D Moazed Molecular cell 63 (2), 191-205, 2016 | 25 | 2016 |
Robust, durable gene activation in vivo via mRNA-encoded activators JP Beyersdorf, S Bawage, N Iglesias, HE Peck, RA Hobbs, JA Wroe, ... ACS nano 16 (4), 5660-5671, 2022 | 20 | 2022 |
Silencing repetitive DNA N Iglesias, D Moazed Elife 6, e29503, 2017 | 19 | 2017 |
Epigenome editing technologies for discovery and medicine SR McCutcheon, D Rohm, N Iglesias, CA Gersbach Nature Biotechnology 42 (8), 1199-1217, 2024 | 16 | 2024 |