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Gareth Jenkins
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NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials
N Singh, B Manshian, GJS Jenkins, SM Griffiths, PM Williams, ...
Biomaterials 30 (23-24), 3891-3914, 2009
14752009
Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION)
N Singh, GJS Jenkins, R Asadi, SH Doak
Nano reviews 1 (1), 5358, 2010
12722010
Graphene field‐effect transistor and its application for electronic sensing
B Zhan, C Li, J Yang, G Jenkins, W Huang, X Dong
Small 10 (20), 4042-4065, 2014
3992014
Confounding experimental considerations in nanogenotoxicology
SH Doak, SM Griffiths, B Manshian, N Singh, PM Williams, AP Brown, ...
Mutagenesis 24 (4), 285-293, 2009
2862009
In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines
SH Doak, B Manshian, GJS Jenkins, N Singh
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 745 (1-2 …, 2012
2772012
Mechanistic influences for mutation induction curves after exposure to DNA-reactive carcinogens
SH Doak, GJS Jenkins, GE Johnson, E Quick, EM Parry, JM Parry
Cancer research 67 (8), 3904-3911, 2007
2182007
The role of iron redox state in the genotoxicity of ultrafine superparamagnetic iron oxide nanoparticles
N Singh, GJS Jenkins, BC Nelson, BJ Marquis, TGG Maffeis, AP Brown, ...
Biomaterials 33 (1), 163-170, 2012
1762012
The bile acid deoxycholic acid (DCA) at neutral pH activates NF-κB and induces IL-8 expression in oesophageal cells in vitro
GJS Jenkins, K Harries, SH Doak, A Wilmes, AP Griffiths, JN Baxter, ...
Carcinogenesis 25 (3), 317-323, 2004
1722004
Deoxycholic acid at neutral and acid pH, is genotoxic to oesophageal cells through the induction of ROS: the potential role of anti-oxidants in Barrett's oesophagus
GJS Jenkins, FR D'Souza, SH Suzen, ZS Eltahir, SA James, JM Parry, ...
Carcinogenesis 28 (1), 136-142, 2007
1542007
Genetic pathways involved in the progression of Barrett's metaplasia to adenocarcinoma
GJS Jenkins, SH Doak, JM Parry, FR D'Souza, AP Griffiths, JN Baxter
British Journal of Surgery 89 (7), 824-837, 2002
1462002
Do dose response thresholds exist for genotoxic alkylating agents?
GJS Jenkins, SH Doak, GE Johnson, E Quick, EM Waters, JM Parry
Mutagenesis 20 (6), 389-398, 2005
1402005
A three-dimensional in vitro HepG2 cells liver spheroid model for genotoxicity studies
UK Shah, J de Oliveira Mallia, N Singh, KE Chapman, SH Doak, ...
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 825, 51-58, 2018
1232018
Critical review of the current and future challenges associated with advanced in vitro systems towards the study of nanoparticle (secondary) genotoxicity
SJ Evans, MJD Clift, N Singh, J de Oliveira Mallia, M Burgum, JW Wills, ...
Mutagenesis 32 (1), 233-241, 2017
1132017
Epidermal growth factor receptor (EGFR) is overexpressed in high-grade dysplasia and adenocarcinoma of the esophagus and may represent a biomarker of histological progression …
J Cronin, E McAdam, A Danikas, C Tselepis, P Griffiths, J Baxter, ...
Official journal of the American College of Gastroenterology| ACG 106 (1), 46-56, 2011
1062011
The bile acid deoxycholic acid has a non-linear dose response for DNA damage and possibly NF-κB activation in oesophageal cells, with a mechanism of action involving ROS
GJS Jenkins, J Cronin, A Alhamdani, N Rawat, F D'souza, T Thomas, ...
Mutagenesis 23 (5), 399-405, 2008
1022008
Chromosome 4 hyperploidy represents an early genetic aberration in premalignant Barrett’s oesophagus
SH Doak, GJS Jenkins, EM Parry, FR D’souza, AP Griffiths, N Toffazal, ...
Gut 52 (5), 623-628, 2003
842003
Dextran coated ultrafine superparamagnetic iron oxide nanoparticles: compatibility with common fluorometric and colorimetric dyes
SM Griffiths, N Singh, GJS Jenkins, PM Williams, AW Orbaek, AR Barron, ...
Analytical chemistry 83 (10), 3778-3785, 2011
832011
Detection of p53 mutations in precancerous gastric tissue
C Morgan, GJS Jenkins, T Ashton, AP Griffiths, JN Baxter, EM Parry, ...
British journal of cancer 89 (7), 1314-1319, 2003
832003
Differential expression of the MAD2, BUB1 and HSP27 genes in Barrett’s oesophagus—their association with aneuploidy and neoplastic progression
SH Doak, GJS Jenkins, EM Parry, AP Griffiths, JN Baxter, JM Parry
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 547 (1 …, 2004
762004
Genetic toxicity assessment of engineered nanoparticles using a 3D in vitro skin model (EpiDerm™)
JW Wills, N Hondow, AD Thomas, KE Chapman, D Fish, TG Maffeis, ...
Particle and fibre toxicology 13, 1-21, 2015
752015
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