Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation Z Liu, S Zhang, J Gu, Y Tong, Y Li, X Gui, H Long, C Wang, C Zhao, J Lu, ... Nature structural & molecular biology 27 (4), 363-372, 2020 | 150 | 2020 |
Domain movements upon activation of phenylalanine hydroxylase characterized by crystallography and chromatography-coupled small-angle X-ray scattering SP Meisburger, AB Taylor, CA Khan, S Zhang, PF Fitzpatrick, N Ando Journal of the American Chemical Society 138 (20), 6506-6516, 2016 | 134 | 2016 |
Hsp40 proteins phase separate to chaperone the assembly and maintenance of membraneless organelles J Gu, Z Liu, S Zhang, Y Li, W Xia, C Wang, H Xiang, Z Liu, L Tan, Y Fang, ... Proceedings of the National Academy of Sciences 117 (49), 31123-31133, 2020 | 98 | 2020 |
Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease S Zhang, YQ Liu, C Jia, YJ Lim, G Feng, E Xu, H Long, Y Kimura, Y Tao, ... Proceedings of the National Academy of Sciences 118 (26), e2011196118, 2021 | 93 | 2021 |
Without its N-finger, the main protease of severe acute respiratory syndrome coronavirus can form a novel dimer through its C-terminal domain N Zhong, S Zhang, P Zou, J Chen, X Kang, Z Li, C Liang, C Jin, B Xia Journal of Virology 82 (9), 4227-4234, 2008 | 74 | 2008 |
The solution structure of the regulatory domain of tyrosine hydroxylase S Zhang, T Huang, U Ilangovan, AP Hinck, PF Fitzpatrick Journal of molecular biology 426 (7), 1483-1497, 2014 | 64 | 2014 |
Mechanistic insights into the switch of αB-crystallin chaperone activity and self-multimerization Z Liu, C Wang, Y Li, C Zhao, T Li, D Li, S Zhang, C Liu Journal of Biological Chemistry 293 (38), 14880-14890, 2018 | 54 | 2018 |
Structural basis of the interplay between α-synuclein and Tau in regulating pathological amyloid aggregation J Lu, S Zhang, X Ma, C Jia, Z Liu, C Huang, C Liu, D Li Journal of Biological Chemistry 295 (21), 7470-7480, 2020 | 52 | 2020 |
Three-dimensional domain swapping as a mechanism to lock the active conformation in a super-active octamer of SARS-CoV main protease S Zhang, N Zhong, F Xue, X Kang, X Ren, J Chen, C Jin, Z Lou, B Xia Protein & cell 1, 371-383, 2010 | 52 | 2010 |
Hsp70 chaperones TDP-43 in dynamic, liquid-like phase and prevents it from amyloid aggregation J Gu, C Wang, R Hu, Y Li, S Zhang, Y Sun, Q Wang, D Li, Y Fang, C Liu Cell Research 31 (9), 1024-1027, 2021 | 50 | 2021 |
Different heat shock proteins bind α-Synuclein with distinct mechanisms and synergistically prevent its amyloid aggregation C Jia, X Ma, Z Liu, J Gu, X Zhang, D Li, S Zhang Frontiers in neuroscience 13, 1124, 2019 | 44 | 2019 |
Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly C Wang, J Tu, S Zhang, B Cai, Z Liu, S Hou, Q Zhong, X Hu, W Liu, G Li, ... Nature communications 11 (1), 1531, 2020 | 42 | 2020 |
Foldon unfolding mediates the interconversion between Mpro-C monomer and 3D domain-swapped dimer X Kang, N Zhong, P Zou, S Zhang, C Jin, B Xia Proceedings of the National Academy of Sciences 109 (37), 14900-14905, 2012 | 40 | 2012 |
C‐terminal domain of SARS‐CoV main protease can form a 3D domain‐swapped dimer N Zhong, S Zhang, F Xue, X Kang, P Zou, J Chen, C Liang, Z Rao, C Jin, ... Protein Science 18 (4), 839-844, 2009 | 40 | 2009 |
Phenylalanine binding is linked to dimerization of the regulatory domain of phenylalanine hydroxylase S Zhang, KM Roberts, PF Fitzpatrick Biochemistry 53 (42), 6625-6627, 2014 | 37 | 2014 |
Identification of the allosteric site for phenylalanine in rat phenylalanine hydroxylase S Zhang, PF Fitzpatrick Journal of Biological Chemistry 291 (14), 7418-7425, 2016 | 35 | 2016 |
Interaction of RAGE with α-synuclein fibrils mediates inflammatory response of microglia H Long, S Zhang, S Zeng, Y Tong, J Liu, C Liu, D Li Cell Reports 40 (12), 2022 | 31 | 2022 |
In-cell NMR study of Tau and MARK2 phosphorylated Tau S Zhang, C Wang, J Lu, X Ma, Z Liu, D Li, Z Liu, C Liu International Journal of Molecular Sciences 20 (1), 90, 2018 | 31 | 2018 |
Hsp70 exhibits a liquid-liquid phase separation ability and chaperones condensed FUS against amyloid aggregation Y Li, J Gu, C Wang, J Hu, S Zhang, C Liu, S Zhang, Y Fang, D Li Iscience 25 (6), 2022 | 28 | 2022 |
A novel partially open state of SHP2 points to a “multiple gear” regulation mechanism Y Tao, J Xie, Q Zhong, Y Wang, S Zhang, F Luo, F Wen, J Xie, J Zhao, ... Journal of Biological Chemistry 296, 2021 | 28 | 2021 |