Inhibition of estrogen signaling in myeloid cells increases tumor immunity in melanoma B Chakraborty, J Byemerwa, J Shepherd, CN Haines, R Baldi, W Gong, ... The Journal of clinical investigation 131 (23), 2021 | 77 | 2021 |
Endothelial stromelysin1 regulation by the forkhead box-O transcription factors is crucial in the exudative phase of acute lung injury S Artham, F Gao, A Verma, A Alwhaibi, H Sabbineni, S Hafez, A Ergul, ... Pharmacological research 141, 249-263, 2019 | 50 | 2019 |
Akt1 promotes stimuli-induced endothelial-barrier protection through FoxO-mediated tight-junction protein turnover F Gao, S Artham, H Sabbineni, A Al-Azayzih, XD Peng, N Hay, RH Adams, ... Cellular and Molecular Life Sciences 73, 3917-3933, 2016 | 48 | 2016 |
Renin–angiotensin system as a potential therapeutic target in stroke and retinopathy: experimental and clinical evidence AY Fouda, S Artham, AB El-Remessy, SC Fagan Clinical science 130 (4), 221-238, 2016 | 48 | 2016 |
Endothelial Akt1 loss promotes prostate cancer metastasis via β-catenin-regulated tight-junction protein turnover F Gao, A Alwhaibi, S Artham, A Verma, PR Somanath British journal of cancer 118 (11), 1464-1475, 2018 | 46 | 2018 |
The Dysregulated Pharmacology of Clinically Relevant ESR1 Mutants is Normalized by Ligand-activated WT Receptor KJ Andreano, JG Baker, S Park, R Safi, S Artham, S Oesterreich, ... Molecular Cancer Therapeutics 19 (7), 1395-1405, 2020 | 43 | 2020 |
Modulation of long‐term endothelial‐barrier integrity is conditional to the cross‐talk between Akt and Src signaling F Gao, H Sabbineni, S Artham, PR Somanath Journal of cellular physiology 232 (10), 2599-2609, 2017 | 39 | 2017 |
Pharmacological inhibition of β-catenin prevents EndMT in vitro and vascular remodeling in vivo resulting from endothelial Akt1 suppression H Sabbineni, A Verma, S Artham, D Anderson, O Amaka, F Liu, ... Biochemical pharmacology 164, 205-215, 2019 | 33 | 2019 |
Delayed Akt suppression in the lipopolysaccharide-induced acute lung injury promotes resolution that is associated with enhanced effector regulatory T cells S Artham, A Verma, A Alwhaibi, MS Adil, S Manicassamy, DH Munn, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 318 (4 …, 2020 | 26 | 2020 |
PAK1 inhibitor IPA-3 mitigates metastatic prostate cancer-induced bone remodeling A Verma, S Artham, A Alwhaibi, MS Adil, BS Cummings, PR Somanath Biochemical pharmacology 177, 113943, 2020 | 24 | 2020 |
Eosinophilia in cancer and its regulation by sex hormones S Artham, CY Chang, DP McDonnell Trends in Endocrinology & Metabolism 34 (1), 5-20, 2023 | 22 | 2023 |
TNFα induces inflammatory stress response in microvascular endothelial cells via Akt-and P38 MAP kinase-mediated thrombospondin-1 expression A Fairaq, A Goc, S Artham, H Sabbineni, PR Somanath Molecular and cellular biochemistry 406, 227-236, 2015 | 22 | 2015 |
Vascular protective effects of angiotensin receptor blockers: beyond blood pressure S Artham, AY Fouda, AB El-Remessy, SC Fagan Receptors & clinical investigation 2 (3), e774, 2015 | 18 | 2015 |
Patients with acute respiratory distress syndrome exhibit increased stromelysin1 activity in the blood samples S Artham, A Verma, AS Newsome, PR Somanath Cytokine 131, 155086, 2020 | 17 | 2020 |
Nodal pathway activation due to Akt1 suppression is a molecular switch for prostate cancer cell epithelial-to-mesenchymal transition and metastasis A Alwhaibi, A Verma, S Artham, MS Adil, PR Somanath Biochemical pharmacology 168, 1-13, 2019 | 13 | 2019 |
Inducible overexpression of endothelial proNGF as a mouse model to study microvascular dysfunction R Mohamed, M Coucha, SL Elshaer, S Artham, T Lemtalsi, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (3), 746-757, 2018 | 13 | 2018 |
ALK-1 to ALK-5 ratio dictated by the Akt1-β-catenin pathway regulates TGFβ-induced endothelial-to-mesenchymal transition A Verma, S Artham, PR Somanath Gene 768, 145293, 2021 | 11 | 2021 |
Targeting CaMKK2 inhibits actin cytoskeletal assembly to suppress cancer metastasis D Mukherjee, RA Previs, C Haines, M Al Abo, PK Juras, KC Strickland, ... Cancer research 83 (17), 2889-2907, 2023 | 9 | 2023 |
Modulation in the microRNA repertoire is responsible for the stage-specific effects of Akt suppression on murine neuroendocrine prostate cancer A Alwhaibi, F Gao, S Artham, BM Hsia, A Mondal, R Kolhe, PR Somanath Heliyon 4 (9), 2018 | 9 | 2018 |
Regulation of let-7a-5p and miR-199a-5p expression by Akt1 modulates prostate cancer epithelial-to-mesenchymal transition via the transforming growth factor-β pathway A Alwhaibi, V Parvathagiri, A Verma, S Artham, MS Adil, PR Somanath Cancers 14 (7), 1625, 2022 | 6 | 2022 |