Dysregulation of ubiquitin-proteasome system in neurodegenerative diseases Q Zheng, T Huang, L Zhang, Y Zhou, H Luo, H Xu, X Wang Frontiers in aging neuroscience 8, 303, 2016 | 319 | 2016 |
Appoptosin-mediated caspase cleavage of tau contributes to progressive supranuclear palsy pathogenesis Y Zhao, IC Tseng, CJ Heyser, E Rockenstein, M Mante, A Adame, ... Neuron 87 (5), 963-975, 2015 | 105 | 2015 |
Sorting nexin 27 regulates Aβ production through modulating γ-secretase activity X Wang, T Huang, Y Zhao, Q Zheng, RC Thompson, G Bu, Y Zhang, ... Cell reports 9 (3), 1023-1033, 2014 | 81 | 2014 |
Inhibition of PKCδ reduces amyloid-β levels and reverses Alzheimer disease phenotypes Y Du, Y Zhao, C Li, Q Zheng, J Tian, Z Li, TY Huang, W Zhang, H Xu Journal of Experimental Medicine 215 (6), 1665-1677, 2018 | 61 | 2018 |
Trisomy 21–induced dysregulation of microglial homeostasis in Alzheimer’s brains is mediated by USP25 Q Zheng, G Li, S Wang, Y Zhou, K Liu, Y Gao, Y Zhou, L Zheng, L Zhu, ... Science advances 7 (1), eabe1340, 2021 | 48 | 2021 |
Ferritin light chain interacts with PEN-2 and affects γ-secretase activity X Li, Y Liu, Q Zheng, G Yao, P Cheng, G Bu, H Xu, Y Zhang Neuroscience letters 548, 90-94, 2013 | 47 | 2013 |
SNX27 deletion causes hydrocephalus by impairing ependymal cell differentiation and ciliogenesis X Wang, Y Zhou, J Wang, IC Tseng, T Huang, Y Zhao, Q Zheng, Y Gao, ... Journal of Neuroscience 36 (50), 12586-12597, 2016 | 42 | 2016 |
β2-Microglobulin coaggregates with Aβ and contributes to amyloid pathology and cognitive deficits in Alzheimer’s disease model mice Y Zhao, Q Zheng, Y Hong, Y Gao, J Hu, M Lang, H Zhang, Y Zhou, H Luo, ... Nature neuroscience 26 (7), 1170-1184, 2023 | 40 | 2023 |
USP25 inhibition ameliorates Alzheimer’s pathology through regulating APP processing and Aβ generation Q Zheng, B Song, G Li, F Cai, M Wu, Y Zhao, L Jiang, T Guo, M Shen, ... Journal of Clinical Investigation 132 (5), e152170, 2022 | 40 | 2022 |
β2-microglobulin functions as an endogenous NMDAR antagonist to impair synaptic function Y Gao, Y Hong, L Huang, S Zheng, H Zhang, S Wang, Y Yao, Y Zhao, ... Cell 186 (5), 1026-1038. e20, 2023 | 37 | 2023 |
Microglial Tmem59 deficiency impairs phagocytosis of synapse and leads to autism-like behaviors in mice J Meng, L Han, N Zheng, T Wang, H Xu, Y Jiang, Z Wang, Z Liu, Q Zheng, ... Journal of Neuroscience 42 (25), 4958-4979, 2022 | 37 | 2022 |
The neuron-specific protein TMEM59L mediates oxidative stress-induced cell death Q Zheng, X Zheng, L Zhang, H Luo, L Qian, X Fu, Y Liu, Y Gao, M Niu, ... Molecular neurobiology 54, 4189-4200, 2017 | 37 | 2017 |
The role of copper and the copper-related protein CUTA in mediating APP processing and Aβ generation P Hou, G Liu, Y Zhao, Z Shi, Q Zheng, G Bu, H Xu, Y Zhang Neurobiology of aging 36 (3), 1310-1315, 2015 | 31 | 2015 |
The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability F Zeng, X Ma, L Zhu, Q Xu, Y Zeng, Y Gao, G Li, T Guo, H Zhang, X Tang, ... PLoS Biology 17 (12), e3000525, 2019 | 26 | 2019 |
SNX14 deficiency-induced defective axonal mitochondrial transport in Purkinje cells underlies cerebellar ataxia and can be reversed by valproate H Zhang, Y Hong, W Yang, R Wang, T Yao, J Wang, K Liu, H Yuan, C Xu, ... National Science Review 8 (7), nwab024, 2021 | 19 | 2021 |
Metabolic reprogramming in astrocytes results in neuronal dysfunction in intellectual disability H Zhang, Q Zheng, T Guo, S Zhang, S Zheng, R Wang, Q Deng, G Yang, ... Molecular Psychiatry, 2022 | 18 | 2022 |
Alzheimer's disease: insights into pathology, molecular mechanisms, and therapy Q Zheng, X Wang Protein & Cell, pwae026, 2024 | 9 | 2024 |
Snx27 Deletion Promotes Recovery From Spinal Cord Injury by Neuroprotection and Reduces Macrophage/Microglia Proliferation Y Zeng, N Wang, T Guo, Q Zheng, S Wang, S Wu, X Li, J Wu, Z Chen, ... Frontiers in Neurology 9, 1059, 2018 | 9 | 2018 |
Overexpression of Human SNX27 Enhances Learning and Memory Through Modulating Synaptic Plasticity in Mice Y Huo, Y Gao, Q Zheng, D Zhao, T Guo, S Zhang, Y Zeng, Y Cheng, H Gu, ... Frontiers in Cell and Developmental Biology 8, 595357, 2020 | 5 | 2020 |
Erratum: Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis (Neuron (2015) 87 (5)(963–975),(S089662731500714X),(10.1016/j … Y Zhao, IC Tseng, CJ Heyser, E Rockenstein, M Mante, A Adame, ... Neuron 112 (23), 3984-3985, 2024 | | 2024 |