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Alfredo M Valencia
Alfredo M Valencia
Stanford Science Fellow, Ford Foundation Fellow, Stanford University
Geverifieerd e-mailadres voor stanford.edu - Homepage
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Modular organization and assembly of SWI/SNF family chromatin remodeling complexes
N Mashtalir, AR D’Avino, BC Michel, J Luo, J Pan, JE Otto, HJ Zullow, ...
Cell 175 (5), 1272-1288. e20, 2018
6592018
A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation
BC Michel, AR D’Avino, SH Cassel, N Mashtalir, ZM McKenzie, ...
Nature cell biology 20 (12), 1410-1420, 2018
3632018
Long-term maturation of human cortical organoids matches key early postnatal transitions
A Gordon, SJ Yoon, SS Tran, CD Makinson, JY Park, J Andersen, ...
Nature neuroscience 24 (3), 331-342, 2021
2962021
SMARCB1 is required for widespread BAF complex–mediated activation of enhancers and bivalent promoters
RT Nakayama, JL Pulice, AM Valencia, MJ McBride, ZM McKenzie, ...
Nature genetics 49 (11), 1613-1623, 2017
2842017
Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence
JA Belk, W Yao, N Ly, KA Freitas, YT Chen, Q Shi, AM Valencia, E Shifrut, ...
Cancer cell 40 (7), 768-786. e7, 2022
2172022
Chromatin regulatory mechanisms and therapeutic opportunities in cancer
AM Valencia, C Kadoch
Nature cell biology 21 (2), 152-161, 2019
2162019
A structural model of the endogenous human BAF complex informs disease mechanisms
N Mashtalir, H Suzuki, DP Farrell, A Sankar, J Luo, M Filipovski, ...
Cell 183 (3), 802-817. e24, 2020
1532020
Dissecting the molecular basis of human interneuron migration in forebrain assembloids from Timothy syndrome
F Birey, MY Li, A Gordon, MV Thete, AM Valencia, O Revah, AM Paşca, ...
Cell stem cell 29 (2), 248-264. e7, 2022
1052022
Recurrent SMARCB1 mutations reveal a nucleosome acidic patch interaction site that potentiates mSWI/SNF complex chromatin remodeling
AM Valencia, CK Collings, HT Dao, RS Pierre, YC Cheng, J Huang, ...
Cell 179 (6), 1342-1356. e23, 2019
1012019
The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma
MJ McBride, N Mashtalir, EB Winter, HT Dao, M Filipovski, AR D’Avino, ...
Nature structural & molecular biology 27 (9), 836-845, 2020
532020
BICRA, a SWI/SNF complex member, is associated with BAF-disorder related phenotypes in humans and model organisms
S Barish, TS Barakat, BC Michel, N Mashtalir, JB Phillips, AM Valencia, ...
The American Journal of Human Genetics 107 (6), 1096-1112, 2020
462020
Landscape of mSWI/SNF chromatin remodeling complex perturbations in neurodevelopmental disorders
AM Valencia, A Sankar, PJ van der Sluijs, FK Satterstrom, J Fu, ...
Nature Genetics 55 (8), 1400-1412, 2023
392023
Chromatin dynamics in human brain development and disease
AM Valencia, SP Pașca
Trends in cell biology 32 (2), 98-101, 2022
152022
The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression
G Mas, N Man, Y Nakata, C Martinez-Caja, D Karl, F Beckedorff, F Tamiro, ...
The Journal of clinical investigation 133 (13), 2024
92024
Author Correction: The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma
MJ McBride, N Mashtalir, EB Winter, HT Dao, M Filipovski, AR D’Avino, ...
Nature Structural & Molecular Biology 28 (1), 118, 2020
32020
Midline Assembloids Reveal Regulators of Human Axon Guidance
MM Onesto, ND Amin, C Pan, X Chen, N Reis, AM Valencia, Z Hudacova, ...
bioRxiv, 2024.06. 26.600229, 2024
12024
Compositions comprising modified smarcb1 and uses thereof
C Kadoch, AM Valencia
US Patent App. 17/770,464, 2022
2022
Biochemistry, Structure, and Function of SMARCB1-mutant mSWI/SNF Chromatin Remodeling Complexes in Human Disease
AM Valencia
2020
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Artikelen 1–18