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Gopala Krishna Jarugumilli
Gopala Krishna Jarugumilli
Harvard Medical School/MGH
Geverifieerd e-mailadres voor mgh.harvard.edu
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Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway
PY Chan, X Han, B Zheng, M DeRan, J Yu, GK Jarugumilli, H Deng, ...
Nature chemical biology 12 (4), 282-289, 2016
2662016
Protein lipidation in cell signaling and diseases: function, regulation, and therapeutic opportunities
B Chen, Y Sun, J Niu, GK Jarugumilli, X Wu
Cell chemical biology 25 (7), 817-831, 2018
2472018
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis
G Eelen, C Dubois, AR Cantelmo, J Goveia, U Brüning, M DeRan, ...
Nature 561 (7721), 63-69, 2018
2022018
Lats1/2 sustain intestinal stem cells and Wnt activation through TEAD-dependent and independent transcription
Q Li, Y Sun, GK Jarugumilli, S Liu, K Dang, JL Cotton, J Xiol, PY Chan, ...
Cell stem cell 26 (5), 675-692. e8, 2020
1502020
ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity
B Chen, B Zheng, M DeRan, GK Jarugumilli, J Fu, YS Brooks, X Wu
Nature chemical biology 12 (9), 686-693, 2016
1102016
Pharmacological blockade of TEAD–YAP reveals its therapeutic limitation in cancer cells
Y Sun, L Hu, Z Tao, GK Jarugumilli, H Erb, A Singh, Q Li, JL Cotton, ...
Nature Communications 13 (1), 6744, 2022
782022
A simple, nontoxic iron system for the allylation of zinc enolates
GK Jarugumilli, SP Cook
Organic Letters 13 (8), 1904-1907, 2011
442011
Auto-fatty acylation of transcription factor RFX3 regulates ciliogenesis
B Chen, J Niu, J Kreuzer, B Zheng, GK Jarugumilli, W Haas, X Wu
Proceedings of the National Academy of Sciences 115 (36), E8403-E8412, 2018
242018
Studies toward total synthesis of divergolides C and D
S Rasapalli, G Jarugumilli, GR Yarrapothu, JA Golen, AL Rheingold
Organic letters 15 (7), 1736-1739, 2013
242013
Re‐Evaluating the Nucleophilicity of Zinc Enolates in Alkylation Reactions
GK Jarugumilli, C Zhu, SP Cook
European Journal of Organic Chemistry 2012 (9), 1712-1715, 2012
242012
Chemical Probe to Identify the Cellular Targets of the Reactive Lipid Metabolite 2-trans-Hexadecenal
GK Jarugumilli, JR Choi, PY Chan, M Yu, Y Sun, B Chen, J Niu, M DeRan, ...
ACS chemical biology 13 (5), 1130-1136, 2018
172018
Synthesis of the naphthoquinone core of divergolides (C–D) and model studies for elaboration of the ansabridge
S Rasapalli, G Jarugumilli, GR Yarrapothu, JA Golen, AL Rheingold
Tetrahedron Letters 54 (21), 2615-2618, 2013
172013
Chemical probes to directly profile palmitoleoylation of proteins
B Zheng, GK Jarugumilli, B Chen, X Wu
ChemBioChem 17 (21), 2022-2027, 2016
142016
Novel small molecule inhibitors of tead transcription factors
P Maiti, C ABBINENI, KC TALLURI, SK Panigrahi, X Wu, ...
32020
Studies towards the total synthesis of hygrocins A and B
S Rasapalli, G Jarugumilli, GR Yarrapothu, H Ijaz, JA Golen, PG Williard
Tetrahedron Letters 55 (4), 821-825, 2014
32014
Novel small molecule inhibitors of tead transcription factors
X Wu, P Maiti, C Abbineni, KC Talluri, SK Panigrahi, GK Jarugumilli, ...
US Patent App. 17/439,735, 2023
2023
Nouveaux inhibiteurs à petites molécules de facteurs de transcription tead
C Abbineni, GK Jarugumilli, P Maiti, SK Panigrahi, Y Sun, KC Talluri, ...
2022
Back Cover: Chemical Probes to Directly Profile Palmitoleoylation of Proteins (ChemBioChem 21/2016)
B Zheng, GK Jarugumilli, B Chen, X Wu
ChemBioChem 17 (21), 2100-2100, 2016
2016
Synthesis of common macrocyclic intermediate for the divergent synthesis of divergolides and hygrocins
S Rasapalli, U Javed, G Jarugumilli, A Fanfan
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015
2015
Synthesis and evaluation of antibacetrial activity of of analogs of novel ansamycins-divergolides and hygrocins
S Rasapalli, G Jarugumilli, T Opperman
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014
2014
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Artikelen 1–20