A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model GP Lim, F Calon, T Morihara, F Yang, B Teter, O Ubeda, N Salem, ... Journal of Neuroscience 25 (12), 3032-3040, 2005 | 943 | 2005 |
Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model F Calon, GP Lim, F Yang, T Morihara, B Teter, O Ubeda, P Rostaing, ... Neuron 43 (5), 633-645, 2004 | 911 | 2004 |
Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease C Julien, C Tremblay, V Émond, M Lebbadi, N Salem Jr, DA Bennett, ... Journal of Neuropathology & Experimental Neurology 68 (1), 48-58, 2009 | 531 | 2009 |
Novel pharmacological targets for the treatment of Parkinson's disease AHV Schapira, E Bezard, J Brotchie, F Calon, GL Collingridge, B Ferger, ... Nature reviews Drug discovery 5 (10), 845-854, 2006 | 389 | 2006 |
Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease L Zhao, QL Ma, F Calon, ME Harris-White, F Yang, GP Lim, T Morihara, ... Nature neuroscience 9 (2), 234-242, 2006 | 373 | 2006 |
Neuroprotective action of omega-3 polyunsaturated fatty acids against neurodegenerative diseases: evidence from animal studies F Calon, G Cole Prostaglandins, Leukotrienes and Essential Fatty Acids 77 (5-6), 287-293, 2007 | 350 | 2007 |
High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model C Julien, C Tremblay, A Phivilay, L Berthiaume, V Émond, P Julien, ... Neurobiology of aging 31 (9), 1516-1531, 2010 | 331 | 2010 |
Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase-and PPARγ-mediated mechanisms in Alzheimer's disease models Y Zhao, F Calon, C Julien, JW Winkler, NA Petasis, WJ Lukiw, NG Bazan PloS one 6 (1), e15816, 2011 | 317 | 2011 |
Beneficial effects of dietary omega‐3 polyunsaturated fatty acid on toxin‐induced neuronal degeneration in an animal model of Parkinson's disease M Bousquet, M Saint‐Pierre, C Julien, N Salem Jr, F Cicchetti, F Calon The FASEB Journal 22 (4), 1213-1225, 2008 | 312 | 2008 |
Cerebrovascular and blood–brain barrier impairments in Huntington's disease: potential implications for its pathophysiology J Drouin‐Ouellet, SJ Sawiak, G Cisbani, M Lagacé, WL Kuan, ... Annals of neurology 78 (2), 160-177, 2015 | 311 | 2015 |
Dietary n‐3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease F Calon, GP Lim, T Morihara, F Yang, O Ubeda, N Salem Jr, SA Frautschy, ... European Journal of Neuroscience 22 (3), 617-626, 2005 | 306 | 2005 |
Synthesis of pegylated immunonanoparticles JC Olivier, R Huertas, HJ Lee, F Calon, WM Pardridge Pharmaceutical research 19, 1137-1143, 2002 | 286 | 2002 |
Intravenous nonviral gene therapy causes normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism Y Zhang, F Calon, C Zhu, RJ Boado, WM Pardridge Human gene therapy 14 (1), 1-12, 2003 | 283 | 2003 |
Aberrant lipid metabolism in the forebrain niche suppresses adult neural stem cell proliferation in an animal model of Alzheimer’s disease LK Hamilton, M Dufresne, SE Joppé, S Petryszyn, A Aumont, F Calon, ... Cell stem cell 17 (4), 397-411, 2015 | 276 | 2015 |
Diffusion of docosahexaenoic and eicosapentaenoic acids through the blood–brain barrier: an in situ cerebral perfusion study M Ouellet, V Emond, CT Chen, C Julien, F Bourasset, S Oddo, F LaFerla, ... Neurochemistry international 55 (7), 476-482, 2009 | 273 | 2009 |
Increased adenosine A2A receptors in the brain of Parkinson’s disease patients with dyskinesias F Calon, M Dridi, O Hornykiewicz, PJ Bédard, AH Rajput, T Di Paolo Brain 127 (5), 1075-1084, 2004 | 271 | 2004 |
Insulin reverses the high-fat diet–induced increase in brain Aβ and improves memory in an animal model of Alzheimer disease M Vandal, PJ White, C Tremblay, I St-Amour, G Chevrier, V Emond, ... Diabetes 63 (12), 4291-4301, 2014 | 257 | 2014 |
Levodopa-induced motor complications are associated with alterations of glutamate receptors in Parkinson's disease F Calon, AH Rajput, O Hornykiewicz, PJ Bédard, T Di Paolo Neurobiology of disease 14 (3), 404-416, 2003 | 254 | 2003 |
miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo PY Smith, J Hernandez-Rapp, F Jolivette, C Lecours, K Bisht, C Goupil, ... Human molecular genetics 24 (23), 6721-6735, 2015 | 250 | 2015 |
DHA improves cognition and prevents dysfunction of entorhinal cortex neurons in 3xTg-AD mice D Arsenault, C Julien, C Tremblay, F Calon PloS one 6 (2), e17397, 2011 | 234 | 2011 |