DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina JM Zullo, IA Demarco, R Piqué-Regi, DJ Gaffney, CB Epstein, CJ Spooner, ... Cell 149 (7), 1474-1487, 2012 | 503 | 2012 |
Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins JC Harr, TR Luperchio, X Wong, E Cohen, SJ Wheelan, KL Reddy Journal of Cell Biology 208 (1), 33-52, 2015 | 355 | 2015 |
Genome regulation at the peripheral zone: lamina associated domains in development and disease TR Luperchio, X Wong, KL Reddy Current opinion in genetics & development 25, 50-61, 2014 | 80 | 2014 |
NET gains and losses: the role of changing nuclear envelope proteomes in genome regulation X Wong, TR Luperchio, KL Reddy Current Opinion in Cell Biology 28, 105-120, 2014 | 74 | 2014 |
Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis R Papazyan, E Voronina, JR Chapman, TR Luperchio, TM Gilbert, ... Elife 3, e02996, 2014 | 66 | 2014 |
A lamina-associated domain border governs nuclear lamina interactions, transcription, and recombination of the Tcrb locus S Chen, TR Luperchio, X Wong, EB Doan, AT Byrd, KR Choudhury, ... Cell reports 25 (7), 1729-1740. e6, 2018 | 49 | 2018 |
Chromosome conformation paints reveal the role of lamina association in genome organization and regulation TR Luperchio, MEG Sauria, X Wong, MC Gaillard, P Tsang, K Pekrun, ... BioRxiv, 122226, 2017 | 39 | 2017 |
Precocious chondrocyte differentiation disrupts skeletal growth in Kabuki syndrome mice JA Fahrner, WY Lin, RC Riddle, L Boukas, VB DeLeon, S Chopra, SE Lad, ... JCI insight 4 (20), e129380, 2019 | 33 | 2019 |
The repressive genome compartment is established early in the cell cycle before forming the lamina associated domains TR Luperchio, MEG Sauria, VE Hoskins, X Wong, E DeBoy, MC Gaillard, ... BioRxiv, 481598, 2018 | 30 | 2018 |
Deficiency of TET3 leads to a genome-wide DNA hypermethylation episignature in human whole blood MA Levy, DB Beck, K Metcalfe, S Douzgou, S Sithambaram, T Cottrell, ... NPJ Genomic Medicine 6 (1), 92, 2021 | 20 | 2021 |
Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation TR Luperchio, L Boukas, L Zhang, G Pilarowski, J Jiang, A Kalinousky, ... Elife 10, e65884, 2021 | 19 | 2021 |
Prediction of gene activity in early B cell development based on an integrative multi-omics analysis M Heydarian, TR Luperchio, J Cutler, CJ Mitchell, MS Kim, A Pandey, ... Journal of proteomics & bioinformatics 7, 1000302, 2014 | 18 | 2014 |
Senescent stroma induces nuclear deformations in cancer cells via the inhibition of RhoA/ROCK/myosin II-based cytoskeletal tension I Aifuwa, BC Kim, P Kamat, B Starich, A Agrawal, D Tanrioven, ... PNAS nexus 2 (1), pgac270, 2023 | 13 | 2023 |
Haploinsufficiency of KMT2D is sufficient to cause Kabuki syndrome and is compatible with life TR Luperchio, CD Applegate, O Bodamer, HT Bjornsson Molecular Genetics & Genomic Medicine 8 (2), e1072, 2019 | 8 | 2019 |
Extending the spectrum in aortopathy: stenosis to aneurysm TR Luperchio, BA Kozel Current Opinion in Genetics & Development 76, 101962, 2022 | 4 | 2022 |
Peripheral blood DNA methylation and neuroanatomical responses to HDACi treatment that rescues neurological deficits in a Kabuki syndrome mouse model SJ Goodman, TR Luperchio, J Ellegood, E Chater-Diehl, JP Lerch, ... Clinical Epigenetics 15 (1), 172, 2023 | 2 | 2023 |
Neuron-specific chromatin disruption at CpG islands and aging-related regions in Kabuki syndrome mice L Boukas, TR Luperchio, A Razi, KD Hansen, HT Bjornsson Genome research 34 (5), 696-710, 2024 | 1 | 2024 |
Phenotypic findings associated with variation in elastin A Justice, MA Kelly, G Bellus, JD Green, R Zaidi, T Kerrins, N Josyula, ... Human Genetics and Genomics Advances 6 (1), 2025 | | 2025 |
KMT2D Deficiency Causes Sensorineural Hearing Loss in Mice and Humans AJ Kalinousky, TR Luperchio, KM Schrode, JR Harris, L Zhang, ... Genes 15 (1), 48, 2023 | | 2023 |
P216: Missing heritability for supravalvar aortic stenosis identified in long range enhancer for elastin S Procknow, KM Tsang, T Luperchio, C Billington, K Small, A Scheuerle, ... Genetics in Medicine Open 1 (1), 2023 | | 2023 |