| Amide bond bioisosteres: Strategies, synthesis, and successes S Kumari, AV Carmona, AK Tiwari, PC Trippier Journal of medicinal chemistry 63 (21), 12290-12358, 2020 | 438 | 2020 |
| Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications PC Trippier, C McGuigan MedChemComm 1 (3), 183-198, 2010 | 359 | 2010 |
| Target-and mechanism-based therapeutics for neurodegenerative diseases: strength in numbers PC Trippier, K Jansen Labby, DD Hawker, JJ Mataka, RB Silverman Journal of medicinal chemistry 56 (8), 3121-3147, 2013 | 170 | 2013 |
| Aldo-keto reductases and cancer drug resistance TM Penning, S Jonnalagadda, PC Trippier, TL Rižner, M Gottesman Pharmacological Reviews 73 (3), 1150-1171, 2021 | 104 | 2021 |
| Amyloid-binding alcohol dehydrogenase (ABAD) inhibitors for the treatment of Alzheimer’s disease: miniperspective A Morsy, PC Trippier Journal of medicinal chemistry 62 (9), 4252-4264, 2018 | 60 | 2018 |
| Synthesis and antineoplastic evaluation of mitochondrial complex II (succinate dehydrogenase) inhibitors derived from atpenin A5 H Wang, B Huwaimel, K Verma, J Miller, TM Germain, N Kinarivala, ... ChemMedChem 12 (13), 1033-1044, 2017 | 60 | 2017 |
| The oxazolomycins: a structurally novel class of bioactive compounds MG Moloney, PC Trippier, M Yaqoob, Z Wang Current drug discovery technologies 1 (3), 181-199, 2004 | 59 | 2004 |
| Potent and Highly Selective Aldo–Keto Reductase 1C3 (AKR1C3) Inhibitors Act as Chemotherapeutic Potentiators in Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia K Verma, T Zang, TM Penning, PC Trippier Journal of medicinal chemistry 62 (7), 3590-3616, 2019 | 58 | 2019 |
| Proteasome activation is a mechanism for pyrazolone small molecules displaying therapeutic potential in amyotrophic lateral sclerosis PC Trippier, KT Zhao, SG Fox, IT Schiefer, R Benmohamed, J Moran, ... ACS chemical neuroscience 5 (9), 823-829, 2014 | 56 | 2014 |
| Remarkable stereospecific conjugate additions to the Hsp90 inhibitor celastrol L Klaic, PC Trippier, RK Mishra, RI Morimoto, RB Silverman Journal of the American Chemical Society 133 (49), 19634-19637, 2011 | 56 | 2011 |
| DARK classics in chemical neuroscience: methamphetamine TJ Abbruscato, PC Trippier ACS chemical neuroscience 9 (10), 2373-2378, 2018 | 52 | 2018 |
| Selective AKR1C3 inhibitors potentiate chemotherapeutic activity in multiple acute myeloid leukemia (AML) cell lines K Verma, T Zang, N Gupta, TM Penning, PC Trippier ACS medicinal chemistry letters 7 (8), 774-779, 2016 | 50 | 2016 |
| Synthetic strategies for the biotinylation of bioactive small molecules PC Trippier ChemMedChem 8 (2), 190-203, 2013 | 49 | 2013 |
| AKR1C3 inhibitor KV-37 exhibits antineoplastic effects and potentiates enzalutamide in combination therapy in prostate adenocarcinoma cells K Verma, N Gupta, T Zang, P Wangtrakluldee, SK Srivastava, TM Penning, ... Molecular cancer therapeutics 17 (9), 1833-1845, 2018 | 47 | 2018 |
| A multicomponent coupling strategy suitable for the synthesis of the triene component of the oxazolomycin antibiotics PG Bulger, MG Moloney, PC Trippier Organic & biomolecular chemistry 1 (21), 3726-3737, 2003 | 47 | 2003 |
| Passage variation of PC12 cells results in inconsistent susceptibility to externally induced apoptosis N Kinarivala, K Shah, TJ Abbruscato, PC Trippier ACS chemical neuroscience 8 (1), 82-88, 2017 | 46 | 2017 |
| Pivotal role of nitrogen heterocycles in Alzheimer’s disease drug discovery S Kumari, K Maddeboina, RD Bachu, SHS Boddu, PC Trippier, AK Tiwari Drug Discovery Today 27 (10), 103322, 2022 | 43 | 2022 |
| Discovery of aromatic carbamates that confer neuroprotective activity by enhancing autophagy and inducing the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2) N Kinarivala, R Patel, RM Boustany, A Al-Ahmad, PC Trippier Journal of medicinal chemistry 60 (23), 9739-9756, 2017 | 42 | 2017 |
| Selecting good ‘drug-like’properties to optimize small molecule blood-brain barrier penetration P C. Trippier Current medicinal chemistry 23 (14), 1392-1407, 2016 | 39 | 2016 |
| Screening baccharin analogs as selective inhibitors against type 5 17β-hydroxysteroid dehydrogenase (AKR1C3) T Zang, K Verma, M Chen, Y Jin, PC Trippier, TM Penning Chemico-biological interactions 234, 339-348, 2015 | 39 | 2015 |
Nihar KinarivalaMemorial Sloan Kettering Cancer CenterGeverifieerd e-mailadres voor mskcc.org
