Prevalence, attributes, and outcomes of fitness and frailty in community-dwelling older adults: report from the Canadian study of health and aging K Rockwood, SE Howlett, C MacKnight, BL Beattie, H Bergman, R Hébert, ... The Journals of Gerontology Series A: Biological Sciences and Medical …, 2004 | 771 | 2004 |
Sex differences in frailty: a systematic review and meta-analysis EH Gordon, NM Peel, M Samanta, O Theou, SE Howlett, RE Hubbard Experimental gerontology 89, 30-40, 2017 | 625 | 2017 |
A clinical frailty index in aging mice: comparisons with frailty index data in humans JC Whitehead, BA Hildebrand, M Sun, MR Rockwood, RA Rose, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2014 | 450 | 2014 |
Microbial shifts in the aging mouse gut MGI Langille, CJ Meehan, JE Koenig, AS Dhanani, RA Rose, SE Howlett, ... Microbiome 2, 1-12, 2014 | 440 | 2014 |
Standard laboratory tests to identify older adults at increased risk of death SE Howlett, MRH Rockwood, A Mitnitski, K Rockwood BMC medicine 12, 1-8, 2014 | 251 | 2014 |
Responsiveness of goal attainment scaling in a randomized controlled trial of comprehensive geriatric assessment K Rockwood, S Howlett, K Stadnyk, D Carver, C Powell, P Stolee Journal of clinical epidemiology 56 (8), 736-743, 2003 | 240 | 2003 |
The degree of frailty as a translational measure of health in aging SE Howlett, AD Rutenberg, K Rockwood Nature Aging 1 (8), 651-665, 2021 | 224 | 2021 |
A frailty index based on deficit accumulation quantifies mortality risk in humans and in mice K Rockwood, JM Blodgett, O Theou, MH Sun, HA Feridooni, A Mitnitski, ... Scientific reports 7 (1), 43068, 2017 | 224 | 2017 |
Heterogeneity of human aging and its assessment A Mitnitski, SE Howlett, K Rockwood Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2017 | 211 | 2017 |
A procedure for creating a frailty index based on deficit accumulation in aging mice RJ Parks, E Fares, JK MacDonald, MC Ernst, CJ Sinal, K Rockwood, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2012 | 208 | 2012 |
Sex differences in the biology and pathology of the aging heart KM Keller, SE Howlett Canadian Journal of Cardiology 32 (9), 1065-1073, 2016 | 194 | 2016 |
Fifteen years of progress in understanding frailty and health in aging K Rockwood, SE Howlett BMC medicine 16, 1-4, 2018 | 192 | 2018 |
Syntheses, calcium channel agonist-antagonist modulation activities, and voltage-clamp studies of isopropyl 1, 4-dihydro-2, 6-dimethyl-3-nitro-4-pyridinylpyridine-5-carboxylate … D Vo, WC Matowe, M Ramesh, N Iqbal, MW Wolowyk, SE Howlett, ... Journal of medicinal chemistry 38 (15), 2851-2859, 1995 | 183 | 1995 |
Age-related deficit accumulation and the diseases of ageing K Rockwood, SE Howlett Mechanisms of ageing and development 180, 107-116, 2019 | 170 | 2019 |
Sex differences in mechanisms of cardiac excitation–contraction coupling RJ Parks, SE Howlett Pflügers Archiv-European Journal of Physiology 465, 747-763, 2013 | 165 | 2013 |
How cardiomyocyte excitation, calcium release and contraction become altered with age HA Feridooni, KM Dibb, SE Howlett Journal of molecular and cellular cardiology 83, 62-72, 2015 | 163 | 2015 |
A frailty index from common clinical and laboratory tests predicts increased risk of death across the life course JM Blodgett, O Theou, SE Howlett, K Rockwood Geroscience 39, 447-455, 2017 | 160 | 2017 |
Screening for frailty in Canada’s health care system: a time for action J Muscedere, MK Andrew, SM Bagshaw, C Estabrooks, D Hogan, ... Canadian Journal on Aging/La Revue canadienne du vieillissement 35 (3), 281-297, 2016 | 139 | 2016 |
Impact of longevity interventions on a validated mouse clinical frailty index AE Kane, SN Hilmer, D Boyer, K Gavin, D Nines, SE Howlett, R De Cabo, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2016 | 135 | 2016 |
Pediatric cardioplegia strategy results in enhanced calcium metabolism and lower serum troponin T JD O'Brien, SE Howlett, HJ Burton, SB O'Blenes, DS Litz, CLH Friesen The Annals of thoracic surgery 87 (5), 1517-1523, 2009 | 134 | 2009 |