Toxicity testing in the 21st century: progress in the past decade and future perspectives D Krewski, ME Andersen, MG Tyshenko, K Krishnan, T Hartung, ... Archives of toxicology 94, 1-58, 2020 | 308 | 2020 |
Increasing scientific confidence in adverse outcome pathways: application of tailored Bradford-Hill considerations for evaluating weight of evidence RA Becker, GT Ankley, SW Edwards, SW Kennedy, I Linkov, B Meek, ... Regulatory Toxicology and Pharmacology 72 (3), 514-537, 2015 | 272 | 2015 |
Accelerating the pace of chemical risk assessment RJ Kavlock, T Bahadori, TS Barton-Maclaren, MR Gwinn, M Rasenberg, ... Chemical research in toxicology 31 (5), 287-290, 2018 | 201 | 2018 |
Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization K Paul Friedman, M Gagne, LH Loo, P Karamertzanis, T Netzeva, ... Toxicological Sciences 173 (1), 202-225, 2020 | 194 | 2020 |
Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment R Farmahin, A Williams, B Kuo, NL Chepelev, RS Thomas, ... Archives of toxicology 91, 2045-2065, 2017 | 165 | 2017 |
Use of new approach methodologies (NAMs) to meet regulatory requirements for the assessment of industrial chemicals and pesticides for effects on human health AO Stucki, TS Barton-Maclaren, Y Bhuller, JE Henriquez, TR Henry, ... Frontiers in Toxicology 4, 964553, 2022 | 157 | 2022 |
Internationalization of read-across as a validated new approach method (NAM) for regulatory toxicology C Rovida, T Barton-Maclaren, E Benfenati, F Caloni, PC Chandrasekera, ... Altex 37 (4), 579, 2020 | 85 | 2020 |
Genetic toxicology in silico protocol C Hasselgren, E Ahlberg, Y Akahori, A Amberg, LT Anger, F Atienzar, ... Regulatory Toxicology and Pharmacology 107, 104403, 2019 | 71 | 2019 |
Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients MP Dent, E Vaillancourt, RS Thomas, PL Carmichael, G Ouedraogo, ... Regulatory toxicology and pharmacology 125, 105026, 2021 | 65 | 2021 |
A transformative vision for an omics-based regulatory chemical testing paradigm KJ Johnson, SS Auerbach, T Stevens, TS Barton-Maclaren, E Costa, ... Toxicological Sciences 190 (2), 127-132, 2022 | 53 | 2022 |
Integrating in silico models to enhance predictivity for developmental toxicity M Marzo, S Kulkarni, A Manganaro, A Roncaglioni, S Wu, ... Toxicology 370, 127-137, 2016 | 44 | 2016 |
New quantitative structure–activity relationship models improve predictability of Ames mutagenicity for aromatic azo compounds S Manganelli, E Benfenati, A Manganaro, S Kulkarni, TS Barton-Maclaren, ... Toxicological Sciences 153 (2), 316-326, 2016 | 34 | 2016 |
Hexabromocyclododecane (HBCD): A case study applying tiered testing for human health risk assessment AM Gannon, M Moreau, R Farmahin, RS Thomas, TS Barton-Maclaren, ... Food and Chemical Toxicology 131, 110581, 2019 | 32 | 2019 |
The effects of organophosphate esters used as flame retardants and plasticizers on granulosa, Leydig, and spermatogonial cells analyzed using high-content imaging X Wang, T Luu, MA Beal, TS Barton-Maclaren, B Robaire, BF Hales Toxicological Sciences 186 (2), 269-287, 2022 | 31 | 2022 |
Innovation in regulatory approaches for endocrine disrupting chemicals: The journey to risk assessment modernization in Canada TS Barton-Maclaren, M Wade, N Basu, S Bayen, J Grundy, V Marlatt, ... Environmental Research 204, 112225, 2022 | 31 | 2022 |
From vision toward best practices: Evaluating in vitro transcriptomic points of departure for application in risk assessment using a uniform workflow AJF Reardon, R Farmahin, A Williams, MJ Meier, GC Addicks, CL Yauk, ... Frontiers in Toxicology 5, 1194895, 2023 | 30 | 2023 |
Predicting estrogen receptor activation by a group of substituted phenols: An integrated approach to testing and assessment case study F Webster, M Gagné, G Patlewicz, P Pradeep, N Trefiak, RS Judson, ... Regulatory Toxicology and Pharmacology 106, 278-291, 2019 | 29 | 2019 |
Emerging technologies for food and drug safety W Slikker Jr, TA de Souza Lima, D Archella, JB de Silva Junior, ... Regulatory Toxicology and Pharmacology 98, 115-128, 2018 | 28 | 2018 |
Development of an evidence-based risk assessment framework D Krewski, P Saunders-Hastings, RA Baan, TS Barton-Maclaren, ... Altex 39 (4), 667, 2022 | 26 | 2022 |
Implementing in vitro bioactivity data to modernize priority setting of chemical inventories MA Beal, M Gagne, SA Kulkarni, G Patlewicz, RS Thomas Altex 39 (1), 123, 2021 | 26 | 2021 |