Meta-analysis: the effects of smoking on the disposition of two commonly used antipsychotic agents, olanzapine and clozapine Y Tsuda, J Saruwatari, N Yasui-Furukori BMJ open 4 (3), e004216, 2014 | 148 | 2014 |
Impact of CYP2C19 polymorphism on residual platelet reactivity in patients with coronary heart disease during antiplatelet therapy K Yamamoto, S Hokimoto, T Chitose, K Morita, T Ono, K Kaikita, K Tsujita, ... Journal of cardiology 57 (2), 194-201, 2011 | 130 | 2011 |
The epidemiology of NAFLD and lean NAFLD in Japan: a meta-analysis with individual and forecasting analysis, 1995–2040 T Ito, M Ishigami, B Zou, T Tanaka, H Takahashi, M Kurosaki, M Maeda, ... Hepatology international 15, 366-379, 2021 | 128 | 2021 |
Gender differences in the incidence and progression of diabetic retinopathy among Japanese patients with type 2 diabetes mellitus: a clinic-based retrospective longitudinal study A Kajiwara, H Miyagawa, J Saruwatari, A Kita, M Sakata, Y Kawata, ... Diabetes research and clinical practice 103 (3), e7-e10, 2014 | 103 | 2014 |
Influence of the PNPLA3 rs738409 polymorphism on non-alcoholic fatty liver disease and renal function among normal weight subjects K Oniki, J Saruwatari, T Izuka, A Kajiwara, K Morita, M Sakata, K Otake, ... PloS one 10 (7), e0132640, 2015 | 89 | 2015 |
ABO blood type and personality traits in healthy Japanese subjects S Tsuchimine, J Saruwatari, A Kaneda, N Yasui-Furukori PloS one 10 (5), e0126983, 2015 | 71 | 2015 |
A population phenotyping study of three drug‐metabolizing enzymes in Kyushu, Japan, with use of the caffeine test J Saruwatari, K Nakagawa, J Shindo, T Tajiri, M Fujieda, H Yamazaki, ... Clinical Pharmacology & Therapeutics 72 (2), 200-208, 2002 | 60 | 2002 |
Update on the genetic polymorphisms of drug-metabolizing enzymes in antiepileptic drug therapy J Saruwatari, T Ishitsu, K Nakagawa Pharmaceuticals 3 (8), 2709-2732, 2010 | 59 | 2010 |
The disposition of oral amodiaquine in Papua New Guinean children with falciparum malaria FW Hombhanje, I Hwaihwanje, T Tsukahara, J Saruwatari, M Nakagawa, ... British journal of clinical pharmacology 59 (3), 298-301, 2005 | 59 | 2005 |
Phenotype-genotype analysis of CYP1A2 in Japanese patients receiving oral theophylline therapy K Takata, J Saruwatari, N Nakada, M Nakagawa, K Fukuda, F Tanaka, ... European journal of clinical pharmacology 62, 23-28, 2006 | 56 | 2006 |
Sex differences in the renal function decline of patients with type 2 diabetes A Kajiwara, A Kita, J Saruwatari, H Miyazaki, Y Kawata, K Morita, K Oniki, ... Journal of diabetes research 2016 (1), 4626382, 2016 | 48 | 2016 |
Prostaglandin E2-EP4 axis promotes lipolysis and fibrosis in adipose tissue leading to ectopic fat deposition and insulin resistance T Inazumi, K Yamada, N Shirata, H Sato, Y Taketomi, K Morita, H Hohjoh, ... Cell Reports 33 (2), 2020 | 46 | 2020 |
Determination of the optimal concentration of valproic acid in patients with epilepsy: a population pharmacokinetic-pharmacodynamic analysis H Nakashima, K Oniki, M Nishimura, N Ogusu, M Shimomasuda, T Ono, ... Plos one 10 (10), e0141266, 2015 | 44 | 2015 |
Impact of the Superoxide Dismutase 2 Val16Ala Polymorphism on the Relationship between Valproic Acid Exposure and Elevation of γ-Glutamyltransferase in … N Ogusu, J Saruwatari, H Nakashima, M Noai, M Nishimura, M Deguchi, ... PLoS One 9 (11), e111066, 2014 | 44 | 2014 |
Cytochrome P450 2C19 polymorphisms and valproic acid‐induced weight gain M Noai, H Soraoka, A Kajiwara, Y Tanamachi, K Oniki, K Nakagawa, ... Acta Neurologica Scandinavica 133 (3), 216-223, 2016 | 38 | 2016 |
Association between aldehyde dehydrogenase 2 polymorphisms and the incidence of diabetic retinopathy among Japanese subjects with type 2 diabetes mellitus K Morita, J Saruwatari, H Miyagawa, Y Uchiyashiki, K Oniki, M Sakata, ... Cardiovascular Diabetology 12, 1-8, 2013 | 38 | 2013 |
The in-vivo effects of sho-saiko-to, a traditional Chinese herbal medicine, on two cytochrome P450 enzymes (1A2 and 3A) and xanthine oxidase in man J Saruwatari, K Nakagawa, J Shindo, S Nachi, H Echizen, T Ishizaki Journal of pharmacy and pharmacology 55 (11), 1553-1559, 2003 | 38 | 2003 |
CYP2A6 is a principal enzyme involved in hydroxylation of 1, 7-dimethylxanthine, a main caffeine metabolite, in humans M Kimura, H Yamazaki, M Fujieda, K Kiyotani, G Honda, J Saruwatari, ... Drug metabolism and disposition 33 (9), 1361-1366, 2005 | 36 | 2005 |
Effects of CYP2C19 and P450 oxidoreductase polymorphisms on the population pharmacokinetics of clobazam and N-desmethylclobazam in japanese patients with epilepsy J Saruwatari, N Ogusu, M Shimomasuda, H Nakashima, T Seo, ... Therapeutic drug monitoring 36 (3), 302-309, 2014 | 35 | 2014 |
Identification of SARS-CoV-2 Mpro inhibitors containing P1’ 4-fluorobenzothiazole moiety highly active against SARS-CoV-2 N Higashi-Kuwata, K Tsuji, H Hayashi, H Bulut, M Kiso, M Imai, ... Nature Communications 14 (1), 1076, 2023 | 34 | 2023 |