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| Differential GLP-1R binding and activation by peptide and non-peptide agonists X Zhang, MJ Belousoff, P Zhao, AJ Kooistra, TT Truong, SY Ang, ... Molecular Cell 80 (3), 485-500. e7, 2020 | 154 | 2020 |
| Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia CJ Draper-Joyce, R Bhola, J Wang, A Bhattarai, ATN Nguyen, ... Nature 597 (7877), 571-576, 2021 | 129 | 2021 |
| Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice P Pymm, A Adair, LJ Chan, JP Cooney, FL Mordant, CC Allison, E Lopez, ... Proceedings of the National Academy of Sciences 118 (19), e2101918118, 2021 | 128 | 2021 |
| Automated cryo-lamella preparation for high-throughput in-situ structural biology G Buckley, G Gervinskas, C Taveneau, H Venugopal, JC Whisstock, ... Journal of structural biology 210 (2), 107488, 2020 | 91 | 2020 |
| Structural, dynamic, and chemical characterization of a novel S-glycosylated bacteriocin H Venugopal, PJB Edwards, M Schwalbe, JK Claridge, DS Libich, ... Biochemistry 50 (14), 2748-2755, 2011 | 85 | 2011 |
| The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1 SS Pang, C Bayly-Jones, M Radjainia, BA Spicer, RHP Law, AW Hodel, ... Nature communications 10 (1), 4288, 2019 | 79 | 2019 |
| Three-dimensional structure of the toxin-delivery particle antifeeding prophage of Serratia entomophila JB Heymann, JD Bartho, D Rybakova, HP Venugopal, DC Winkler, A Sen, ... Journal of Biological Chemistry 288 (35), 25276-25284, 2013 | 66 | 2013 |
| Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity JI Mobbs, MJ Belousoff, KG Harikumar, SJ Piper, X Xu, SGB Furness, ... PLoS biology 19 (6), e3001295, 2021 | 65 | 2021 |
| Atomic structures of an entire contractile injection system in both the extended and contracted states A Desfosses, H Venugopal, T Joshi, J Felix, M Jessop, H Jeong, J Hyun, ... Nature microbiology 4 (11), 1885-1894, 2019 | 65 | 2019 |
| The first transmembrane region of complement component-9 acts as a brake on its self-assembly BA Spicer, RHP Law, TT Caradoc-Davies, SM Ekkel, C Bayly-Jones, ... Nature Communications 9 (1), 3266, 2018 | 58 | 2018 |
| Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation G Deganutti, YL Liang, X Zhang, M Khoshouei, L Clydesdale, ... Nature communications 13 (1), 92, 2022 | 55 | 2022 |
| Structures of human peroxiredoxin 3 suggest self-chaperoning assembly that maintains catalytic state NA Yewdall, H Venugopal, A Desfosses, V Abrishami, Y Yosaatmadja, ... Structure 24 (7), 1120-1129, 2016 | 52 | 2016 |
| Structural basis for bacterial energy extraction from atmospheric hydrogen R Grinter, A Kropp, H Venugopal, M Senger, J Badley, PR Cabotaje, R Jia, ... Nature 615 (7952), 541-547, 2023 | 48 | 2023 |
| Delivery of femtolitre droplets using surface acoustic wave based atomisation for cryo-EM grid preparation D Ashtiani, H Venugopal, M Belousoff, B Spicer, J Mak, A Neild, ... Journal of structural biology 203 (2), 94-101, 2018 | 48 | 2018 |
| The structure of an infectious immature flavivirus redefines viral architecture and maturation ND Newton, JM Hardy, N Modhiran, LE Hugo, AA Amarilla, S Bibby, ... Science Advances 7 (20), eabe4507, 2021 | 47 | 2021 |
| How IGF-II binds to the human type 1 insulin-like growth factor receptor Y Xu, NS Kirk, H Venugopal, MB Margetts, TI Croll, JJ Sandow, AI Webb, ... Structure 28 (7), 786-798. e6, 2020 | 47 | 2020 |
| A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses JM Hardy, ND Newton, N Modhiran, CAP Scott, H Venugopal, LJ Vet, ... Nature Communications 12 (1), 3266, 2021 | 43 | 2021 |
| The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1 CJ Lupton, C Bayly-Jones, L D’Andrea, C Huang, RB Schittenhelm, ... Nature structural & molecular biology 28 (12), 982-988, 2021 | 42 | 2021 |
| Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain AK Wheatley, P Pymm, R Esterbauer, MH Dietrich, WS Lee, D Drew, ... Cell Reports 37 (2), 2021 | 42 | 2021 |