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Stefan Gröschel
Stefan Gröschel
DKFZ / Department of Hematology, Heidelberg University Hospital
Geverifieerd e-mailadres voor dkfz.de
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A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia
S Gröschel, MA Sanders, R Hoogenboezem, E de Wit, BAM Bouwman, ...
Cell 157 (2), 369-381, 2014
7532014
Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes
PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ...
Cancer cell 29 (3), 379-393, 2016
5582016
Active medulloblastoma enhancers reveal subgroup-specific cellular origins
CY Lin, S Erkek, Y Tong, L Yin, AJ Federation, M Zapatka, P Haldipur, ...
Nature 530 (7588), 57-62, 2016
4252016
High EVI1 Expression Predicts Outcome in Younger Adult Patients With Acute Myeloid Leukemia and Is Associated With Distinct Cytogenetic Abnormalities
S Groeschel, S Lugthart, RF Schlenk, PJM Valk, K Eiwen, C Goudswaard, ...
Journal of Clinical Oncology 28 (12), 2101-2107, 2010
2982010
Clinical, molecular, and prognostic significance of WHO type inv (3)(q21q26. 2)/t (3; 3)(q21; q26. 2) and various other 3q abnormalities in acute myeloid leukemia
S Lugthart, S Gröschel, HB Beverloo, S Kayser, PJM Valk, ...
Journal of clinical oncology 28 (24), 3890-3898, 2010
2952010
Integrative genomic and transcriptomic analysis of leiomyosarcoma
P Chudasama, SS Mughal, MA Sanders, D Hübschmann, I Chung, ...
Nature communications 9 (1), 144, 2018
2722018
Precision oncology based on omics data: the NCT Heidelberg experience
P Horak, B Klink, C Heining, S Gröschel, B Hutter, M Fröhlich, S Uhrig, ...
International journal of cancer 141 (5), 877-886, 2017
1822017
Deregulated Expression of EVI1 Defines a Poor Prognostic Subset of MLL-Rearranged Acute Myeloid Leukemias: A Study of the German-Austrian Acute Myeloid …
S Groeschel, RF Schlenk, J Engelmann, V Rockova, V Teleanu, ...
Journal of clinical oncology 31 (1), 95-103, 2013
1272013
Vascular dendritic cells in giant cell arteritis
CM Weyand, WEI MA‐KRUPA, O Pryshchep, S Gröschel, R Bernardino, ...
Annals of the New York Academy of Sciences 1062 (1), 195-208, 2005
1152005
Mutational spectrum of myeloid malignancies with inv (3)/t (3; 3) reveals a predominant involvement of RAS/RTK signaling pathways
S Gröschel, MA Sanders, R Hoogenboezem, A Zeilemaker, M Havermans, ...
Blood, The Journal of the American Society of Hematology 125 (1), 133-139, 2015
1102015
Pan‐cancer analysis of copy number changes in programmed death‐ligand 1 (PD‐L1, CD274)–associations with gene expression, mutational load, and survival
J Budczies, M Bockmayr, C Denkert, F Klauschen, S Gröschel, ...
Genes, Chromosomes and Cancer 55 (8), 626-639, 2016
1062016
An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation
R Avellino, M Havermans, C Erpelinck, MA Sanders, R Hoogenboezem, ...
Blood, The Journal of the American Society of Hematology 127 (24), 2991-3003, 2016
872016
Defective homologous recombination DNA repair as therapeutic target in advanced chordoma
S Gröschel, D Hübschmann, F Raimondi, P Horak, G Warsow, M Fröhlich, ...
Nature communications 10 (1), 1635, 2019
802019
Integration of genomics and histology revises diagnosis and enables effective therapy of refractory cancer of unknown primary with PDL1 amplification
S Gröschel, M Bommer, B Hutter, J Budczies, D Bonekamp, C Heining, ...
Molecular Case Studies 2 (6), a001180, 2016
742016
Cooperation of BRAFF595L and mutant HRAS in histiocytic sarcoma provides new insights into oncogenic BRAF signaling
M Kordes, M Röring, C Heining, S Braun, B Hutter, D Richter, C Geörg, ...
Leukemia 30 (4), 937-946, 2016
662016
PD-L1 (CD274) copy number gain, expression, and immune cell infiltration as candidate predictors for response to immune checkpoint inhibitors in soft-tissue sarcoma
J Budczies, G Mechtersheimer, C Denkert, F Klauschen, SS Mughal, ...
Oncoimmunology 6 (3), e1279777, 2017
612017
The clinical picture of cachexia: a mosaic of different parameters (experience of 503 patients)
S Schwarz, O Prokopchuk, K Esefeld, S Gröschel, J Bachmann, ...
BMC cancer 17, 1-10, 2017
572017
TLR-mediated induction of negative regulatory ligands on dendritic cells
S Gröschel, KD Piggott, A Vaglio, W Ma-Krupa, K Singh, JJ Goronzy, ...
Journal of Molecular Medicine 86, 443-455, 2008
492008
The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops
S Ottema, R Mulet-Lazaro, C Erpelinck-Verschueren, S van Herk, ...
Nature Communications 12 (1), 5679, 2021
472021
Targeting fibroblast growth factor receptor 1 for treatment of soft-tissue sarcoma
P Chudasama, M Renner, M Straub, SS Mughal, B Hutter, Z Kosaloglu, ...
Clinical cancer research 23 (4), 962-973, 2017
392017
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Artikelen 1–20