Formation and role of exosomes in cancer LT Brinton, HS Sloane, M Kester, KA Kelly Cellular and molecular life sciences 72, 659-671, 2015 | 294 | 2015 |
BRD4 profiling identifies critical chronic lymphocytic leukemia oncogenic circuits and reveals sensitivity to PLX51107, a novel structurally distinct BET inhibitor HG Ozer, D El-Gamal, B Powell, ZA Hing, JS Blachly, B Harrington, ... Cancer discovery 8 (4), 458-477, 2018 | 125 | 2018 |
Development of target-specific liposomes for delivering small molecule drugs after reperfused myocardial infarction SSK Dasa, R Suzuki, M Gutknecht, LT Brinton, Y Tian, E Michaelsson, ... Journal of Controlled Release 220, 556-567, 2015 | 79 | 2015 |
Synergistic effect of BCL2 and FLT3 co-inhibition in acute myeloid leukemia LT Brinton, P Zhang, K Williams, D Canfield, S Orwick, S Sher, ... Journal of hematology & oncology 13, 1-10, 2020 | 56 | 2020 |
PHASTpep: analysis software for discovery of cell-selective peptides via phage display and next-generation sequencing LT Brinton, DK Bauknight, SSK Dasa, KA Kelly PloS one 11 (5), e0155244, 2016 | 44 | 2016 |
Gilteritinib Inhibits Glutamine Uptake and Utilization in FLT3-ITD–Positive AML ME Zavorka Thomas, X Lu, Z Talebi, JY Jeon, DR Buelow, AA Gibson, ... Molecular cancer therapeutics 20 (11), 2207-2217, 2021 | 38 | 2021 |
Plectin in cancer: from biomarker to therapeutic target SM Perez, LT Brinton, KA Kelly Cells 10 (9), 2246, 2021 | 37 | 2021 |
Targeting DNA damage repair functions of two histone deacetylases, HDAC8 and SIRT6, sensitizes acute myeloid leukemia to NAMPT inhibition P Zhang, LT Brinton, K Williams, S Sher, S Orwick, L Tzung-Huei, ... Clinical Cancer Research 27 (8), 2352-2366, 2021 | 30 | 2021 |
Metastatic biomarker discovery through proteomics LT Brinton, TA Brentnall, JA Smith, KA Kelly Cancer genomics & proteomics 9 (6), 345-355, 2012 | 26 | 2012 |
Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter’s transformation ZA Hing, JS Walker, EC Whipp, L Brinton, M Cannon, P Zhang, S Sher, ... Nature communications 14 (1), 97, 2023 | 24 | 2023 |
TP-0903 is active in models of drug-resistant acute myeloid leukemia JY Jeon, DR Buelow, DA Garrison, M Niu, ED Eisenmann, KM Huang, ... JCI insight 5 (23), e140169, 2020 | 24 | 2020 |
Cotargeting of XPO1 enhances the antileukemic activity of midostaurin and gilteritinib in acute myeloid leukemia LT Brinton, S Sher, K Williams, D Canfield, S Orwick, R Wasmuth, ... Cancers 12 (6), 1574, 2020 | 20 | 2020 |
Novel SF3B1 in-frame deletions result in aberrant RNA splicing in CLL patients AA Agrawal, M Seiler, LT Brinton, R Mantel, R Lapalombella, JA Woyach, ... Blood Advances 1 (15), 995-1000, 2017 | 16 | 2017 |
Targeting OXPHOS de novo purine synthesis as the nexus of FLT3 inhibitor–mediated synergistic antileukemic actions P Zhang, LT Brinton, M Gharghabi, S Sher, K Williams, M Cannon, ... Science Advances 8 (37), eabp9005, 2022 | 15 | 2022 |
BRD4 profiling identifies critical chronic lymphocytic leukemia oncogenic circuits and reveals sensitivity to PLX51107, a novel structurally distinct BET inhibitor. Cancer … HG Ozer, D El-Gamal, B Powell, ZA Hing, JS Blachly, B Harrington, ... DOI: https://doi. org/10.1158/2159-8290. CD-17-0902. PMID: https://www. ncbi …, 0 | 14 | |
Large-scale drug screen identifies FDA-approved drugs for repurposing in sickle-cell disease M Cannon, H Phillips, S Smith, K Williams, L Brinton, C Gregory, ... Journal of Clinical Medicine 9 (7), 2276, 2020 | 9 | 2020 |
BRD4 profiling identifies critical chronic lymphocytic leukemia oncogenic circuits and reveals sensitivity to PLX51107, a novel structurally distinct BET inhibitor. Cancer … HG Ozer, D El-Gamal, B Powell, ZA Hing, JS Blachly, B Harrington, ... CD-17-0902, 2018 | 9 | 2018 |
Registered report: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment J Evans, A Essex, H Xin, N Amitai, L Brinton, E Griner, ... Elife 4, 468-476, 2015 | 9 | 2015 |
Physical model reproduction from ct scans classified according to gender, ethnicity, and age-biomed 2009. LA Taylor, KA Danelson, FS Gayzik, KL Loftis, JD Stitzel Biomedical Sciences Instrumentation 45, 370-375, 2009 | 4 | 2009 |
Role of mutant p53 in the progression of chronic lymphocytic leukemia J Ravikrishnan, TH Lai, E Muhowski, L Brinton, K Williams, A Thompson, ... Blood 134, 2526, 2019 | 3 | 2019 |