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Michael F. Hughes
Michael F. Hughes
Center for Computational Toxicology and Exposure, U.S. Environmental Protection Agency
Geverifieerd e-mailadres voor epa.gov
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Arsenic toxicity and potential mechanisms of action
MF Hughes
Toxicology letters 133 (1), 1-16, 2002
22092002
Arsenic exposure and toxicology: a historical perspective
MF Hughes, BD Beck, Y Chen, AS Lewis, DJ Thomas
Toxicological sciences 123 (2), 305-332, 2011
15632011
Prostaglandin H synthase and xenobiotic oxidation.
TE Eling, DC Thompson, GL Foureman, JF Curtis, MF Hughes
Annual Review of Pharmacology and Toxicology 30, 1-45, 1990
3971990
Biomarkers of exposure: a case study with inorganic arsenic
MF Hughes
Environmental health perspectives 114 (11), 1790-1796, 2006
3672006
The next generation blueprint of computational toxicology at the US Environmental Protection Agency
RS Thomas, T Bahadori, TJ Buckley, J Cowden, C Deisenroth, ...
Toxicological Sciences 169 (2), 317-332, 2019
3042019
A concise review of the toxicity and carcinogenicity of dimethylarsinic acid
EM Kenyon, MF Hughes
Toxicology 160 (1-3), 227-236, 2001
2442001
In vitro metabolism of pyrethroid pesticides by rat and human hepatic microsomes and cytochrome p450 isoforms
EJ Scollon, JM Starr, SJ Godin, MJ DeVito, MF Hughes
Drug Metabolism and Disposition 37 (1), 221-228, 2009
2382009
Relative bioavailability and bioaccessibility and speciation of arsenic in contaminated soils
KD Bradham, KG Scheckel, CM Nelson, PE Seales, GE Lee, MF Hughes, ...
Environmental health perspectives 119 (11), 1629-1634, 2011
2082011
The use of biomonitoring data in exposure and human health risk assessment: benzene case study
SM Arnold, J Angerer, PJ Boogaard, MF Hughes, RB O’Lone, SH Robison, ...
Critical reviews in toxicology 43 (2), 119-153, 2013
1932013
Arsenic and arsenic compounds
A Gomez-Caminero, PD Howe, M Hughes, E Kenyon, DR Lewis, M Moore, ...
World health organization, 2001
193*2001
Disruption of the arsenic (+ 3 oxidation state) methyltransferase gene in the mouse alters the phenotype for methylation of arsenic and affects distribution and retention of …
Z Drobna, H Naranmandura, KM Kubachka, BC Edwards, K Herbin-Davis, ...
Chemical research in toxicology 22 (10), 1713-1720, 2009
1822009
Accumulation and metabolism of arsenic in mice after repeated oral administration of arsenate
MF Hughes, EM Kenyon, BC Edwards, CT Mitchell, LM Del Razo, ...
Toxicology and applied pharmacology 191 (3), 202-210, 2003
1662003
Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics
JF Wambaugh, MF Hughes, CL Ring, DK MacMillan, J Ford, TR Fennell, ...
Toxicological Sciences 163 (1), 152-169, 2018
1602018
Issue paper on the human health effects of metals
R Goyer
US Environmental Protection Agency, 2004
1512004
Identification of rat and human cytochrome p450 isoforms and a rat serum esterase that metabolize the pyrethroid insecticides deltamethrin and esfenvalerate
SJ Godin, JA Crow, EJ Scollon, MF Hughes, MJ DeVito, MK Ross
Drug Metabolism and Disposition 35 (9), 1664-1671, 2007
1502007
Tissue distribution and urinary excretion of inorganic arsenic and its methylated metabolites in C57BL6 mice following subchronic exposure to arsenate in drinking water
EM Kenyon, MF Hughes, BM Adair, JH Highfill, EA Crecelius, HJ Clewell, ...
Toxicology and applied pharmacology 232 (3), 448-455, 2008
1332008
Species differences in the in vitro metabolism of deltamethrin and esfenvalerate: differential oxidative and hydrolytic metabolism by humans and rats
SJ Godin, EJ Scollon, MF Hughes, PM Potter, MJ DeVito, MK Ross
Drug Metabolism and Disposition 34 (10), 1764-1771, 2006
1152006
Tissue distribution and urinary excretion of inorganic arsenic and its methylated metabolites in mice following acute oral administration of arsenate
EM Kenyon, LM Del Razo, MF Hughes
Toxicological Sciences 85 (1), 468-475, 2005
1022005
Physiologically based pharmacokinetic modeling of deltamethrin: development of a rat and human diffusion-limited model
SJ Godin, MJ DeVito, MF Hughes, DG Ross, EJ Scollon, JM Starr, ...
Toxicological Sciences 115 (2), 330-343, 2010
1002010
Comprehensive analysis of arsenic metabolites by pH-specific hydride generation atomic absorption spectrometry
V Devesa, LM Del Razo, B Adair, Z Drobná, SB Waters, MF Hughes, ...
Journal of Analytical Atomic Spectrometry 19 (11), 1460-1467, 2004
952004
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Artikelen 1–20