| miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and maydownregulate the high affinity cationic amino acid transporter CAT-1 J Chang, E Nicolas, D Marks, C Sander, A Lerro, MA Buendia, C Xu, ... RNA biology 1 (2), 106-113, 2004 | 1057 | 2004 |
| Diclofenac toxicity to hepatocytes: a role for drug metabolism in cell toxicity R Bort, X Ponsoda, R Jover, MJ Gómez-Lechón, JV Castell The Journal of pharmacology and experimental therapeutics 288 (1), 65-72, 1999 | 369 | 1999 |
| Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development R Bort, M Signore, K Tremblay, JPM Barbera, KS Zaret Developmental biology 290 (1), 44-56, 2006 | 361 | 2006 |
| Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas R Bort, JP Martinez-Barbera, RSP Beddington, KS Zaret Oxford University Press for The Company of Biologists Limited 131 (4), 797-806, 2004 | 344 | 2004 |
| Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways R Bort, K Macé, A Boobis, MJ Gómez-Lechón, A Pfeifer, J Castell Biochemical pharmacology 58 (5), 787-796, 1999 | 328 | 1999 |
| Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming J Prieto, M León, X Ponsoda, R Sendra, R Bort, R Ferrer-Lorente, A Raya, ... Nature communications 7 (1), 11124, 2016 | 282 | 2016 |
| Down‐regulation of human CYP3A4 by the inflammatory signal interleukin 6: molecular mechanism and transcription factors involved R Jover, R Bort, MJ Gómez‐Lechón, JV Castell The FASEB Journal 16 (13), 1-29, 2002 | 280 | 2002 |
| Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: a study using adenovirus‐mediated antisense targeting R Jover, R Bort, MJ Gómez‐Lechón, JV Castell Hepatology 33 (3), 668-675, 2001 | 277 | 2001 |
| Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture RL Gieseck III, NRF Hannan, R Bort, NA Hanley, RAL Drake, ... PloS one 9 (1), e86372, 2014 | 241 | 2014 |
| Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent E Siewert, R Bort, R Kluge, PC Heinrich, J Castell, R Jover Hepatology 32 (1), 49-55, 2000 | 220 | 2000 |
| Long‐term expression of differentiated functions in hepatocytes cultured in three‐dimensional collagen matrix MJ Gómez‐Lechón, R Jover, T Donato, X Ponsoda, C Rodriguez, ... Journal of cellular physiology 177 (4), 553-562, 1998 | 197 | 1998 |
| Re-expression of C/EBPα induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells R Jover, R Bort, MJ Gómez-Lechón, JV Castell FEBS letters 431 (2), 227-230, 1998 | 173 | 1998 |
| Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein α and hepatocyte nuclear factor-3γ C Rodriguez-Antona, R Bort, R Jover, N Tindberg, M Ingelman-Sundberg, ... Molecular pharmacology 63 (5), 1180-1189, 2003 | 135 | 2003 |
| Metabolism of aceclofenac in humans. R Bort, X Ponsoda, E Carrasco, MJ Gomez-Lechon, JV Castell Drug metabolism and disposition 24 (8), 834-841, 1996 | 122 | 1996 |
| Role of hepatocyte nuclear factor 3γ in the expression of human CYP2C genes R Bort, MJ Gómez-Lechón, JV Castell, R Jover Archives of biochemistry and biophysics 426 (1), 63-72, 2004 | 72 | 2004 |
| The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays M Vinken, T Doktorova, H Ellinger-Ziegelbauer, HJ Ahr, E Lock, ... Mutation Research/Reviews in Mutation Research 659 (3), 202-210, 2008 | 68 | 2008 |
| In vitro investigation of the molecular mechanisms of hepatotoxicity JV Castell, MJ Gómez-Lechón, X Ponsoda, R Bort Applied Toxicology: Approaches Through Basic Science: Proceedings of the …, 1997 | 68 | 1997 |
| Comparative metabolism of the nonsteroidal antiinflammatory drug, aceclofenac, in the rat, monkey, and human. R Bort, X Ponsoda, E Carrasco, MJ Gomez-Lechon, JV Castell Drug Metabolism and Disposition 24 (9), 969-975, 1996 | 68 | 1996 |
| The use of cultured hepatocytes to investigate the mechanisms of drug hepatotoxicity JV Castell, MJ Gomez-Lechon, X Ponsoda, R Bort Cell Biology and Toxicology 13, 331-338, 1997 | 64 | 1997 |
| Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models TY Doktorova, R Yildirimman, M Vinken, M Vilardell, T Vanhaecke, ... Carcinogenesis 34 (6), 1393-1402, 2013 | 60 | 2013 |
