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Prabesh Bhattarai, PhD
Prabesh Bhattarai, PhD
Columbia University Irving Medical Center
Geverifieerd e-mailadres voor cumc.columbia.edu
Titel
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IL4/STAT6 signaling activates neural stem cell proliferation and neurogenesis upon Amyloid-β42 aggregation in adult zebrafish brain
P Bhattarai, AK Thomas, MI Cosacak, C Papadimitriou, V Mashkaryan, ...
Cell reports 17 (4), 941-948, 2016
1632016
3D culture method for Alzheimer's disease modeling reveals interleukin-4 rescues Aβ42-induced loss of human neural stem cell plasticity
C Papadimitriou, H Celikkaya, MI Cosacak, V Mashkaryan, L Bray, ...
Developmental cell 46 (1), 85-101. e8, 2018
1402018
Single-cell transcriptomics analyses of neural stem cell heterogeneity and contextual plasticity in a zebrafish brain model of amyloid toxicity
MI Cosacak, P Bhattarai, S Reinhardt, A Petzold, A Dahl, Y Zhang, C Kizil
Cell reports 27 (4), 1307-1318. e3, 2019
1182019
Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer’s model of adult zebrafish brain
P Bhattarai, MI Cosacak, V Mashkaryan, S Demir, SD Popova, ...
PLoS biology 18 (1), e3000585, 2020
1082020
The effects of aging on Amyloid-β42-induced neurodegeneration and regeneration in adult zebrafish brain
P Bhattarai, AK Thomas, Y Zhang, C Kizil
Neurogenesis 4 (1), e1322666, 2017
852017
Focus: The aging brain: neural stem/progenitor cells in Alzheimer’s disease
G Tincer, V Mashkaryan, P Bhattarai, C Kizil
The Yale journal of biology and medicine 89 (1), 23, 2016
812016
Modeling amyloid-β42 toxicity and neurodegeneration in adult zebrafish brain
P Bhattarai, AK Thomas, MI Cosacak, C Papadimitriou, V Mashkaryan, ...
Journal of visualized experiments: JoVE, 2017
642017
Nerve growth factor modulates LPS-induced microglial glycolysis and inflammatory responses
G Fodelianaki, F Lansing, P Bhattarai, M Troullinaki, MA Zeballos, ...
Experimental cell research 377 (1-2), 10-16, 2019
622019
Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo
L Reinhardt, S Kordes, P Reinhardt, M Glatza, M Baumann, HCA Drexler, ...
Stem cell reports 12 (3), 502-517, 2019
592019
Alzheimer’s disease, neural stem cells and neurogenesis: cellular phase at single-cell level
MI Cosacak, P Bhattarai, C Kizil
Neural Regeneration Research 15 (5), 824-827, 2020
462020
Human TAUP301L overexpression results in TAU hyperphosphorylation without neurofibrillary tangles in adult zebrafish brain
MI Cosacak, P Bhattarai, L Bocova, T Dzewas, V Mashkaryan, ...
Scientific Reports 7 (1), 12959, 2017
442017
FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer’s disease
AJ Lee, NS Raghavan, P Bhattarai, T Siddiqui, S Sariya, ...
Acta Neuropathologica, 1-21, 2022
342022
GATA3 promotes the neural progenitor state but not neurogenesis in 3D traumatic injury model of primary human cortical astrocytes
H Celikkaya, MI Cosacak, C Papadimitriou, S Popova, P Bhattarai, ...
Frontiers in cellular neuroscience 13, 23, 2019
332019
Efficient cargo delivery into adult brain tissue using short cell-penetrating peptides
C Kizil, A Iltzsche, AK Thomas, P Bhattarai, Y Zhang, M Brand
PLoS One 10 (4), e0124073, 2015
30*2015
Single Cell/Nucleus Transcriptomics Comparison in Zebrafish and Humans Reveals Common and Distinct Molecular Responses to Alzheimer’s Disease
MI Cosacak, P Bhattarai, PL De Jager, V Menon, G Tosto, C Kizil
Cells 11 (11), 1807, 2022
282022
Is Alzheimer’s also a stem cell disease?–The zebrafish perspective
C Kizil, P Bhattarai
Frontiers in Cell and Developmental Biology 6, 159, 2018
242018
Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer’s Disease
B Turgutalp, P Bhattarai, T Ercetin, C Luise, R Reis, EE Gurdal, A Isaak, ...
Journal of Medicinal Chemistry 65 (18), 12292-12318, 2022
222022
KYNA/Ahr Signaling Suppresses Neural Stem Cell Plasticity and Neurogenesis in Adult Zebrafish Model of Alzheimer’s Disease
T Siddiqui, P Bhattarai, S Popova, MI Cosacak, S Sariya, Y Zhang, ...
Cells 10 (10), 2748, 2021
212021
Type 1 Interleukin-4 Signaling Obliterates Mouse Astroglia in vivo but Not in vitro
V Mashkaryan, T Siddiqui, S Popova, MI Cosacak, P Bhattarai, K Brandt, ...
Frontiers in Cell and Developmental Biology 8, 114, 2020
212020
Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer’s disease
P Bhattarai, TI Gunasekaran, ME Belloy, D Reyes-Dumeyer, D Jülich, ...
Acta Neuropathologica 147 (1), 1-20, 2024
192024
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Artikelen 1–20