Targeting the gatekeeper MET146 of C-Jun N-Terminal Kinase 3 induces a bivalent halogen/chalcogen bond A Lange, M Günther, FM Büttner, MO Zimmermann, J Heidrich, ... Journal of the American Chemical Society 137 (46), 14640-14652, 2015 | 91 | 2015 |
Trisubstituted imidazoles with a rigidized hinge binding motif act as single digit nM inhibitors of clinically relevant EGFR L858R/T790M and L858R/T790M/C797S mutants: An … M Juchum, M Günther, E Doering, A Sievers-Engler, M Lämmerhofer, ... Journal of Medicinal Chemistry, 2017 | 81 | 2017 |
Tri-and Tetrasubstituted Pyridinylimidazoles as Covalent Inhibitors of c-Jun N-Terminal Kinase 3 F Muth, A El-Gokha, F Ansideri, M Eitel, E Döring, A Sievers-Engler, ... Journal of medicinal chemistry 60 (2), 594-607, 2017 | 48 | 2017 |
Methods for the comprehensive structural elucidation of constitution and stereochemistry of lipopeptides H Gerhardt, A Sievers-Engler, G Jahanshah, Z Pataj, F Ianni, H Gross, ... Journal of Chromatography A 1428, 280-291, 2016 | 37 | 2016 |
Design, Synthesis, and Biological Evaluation of Novel Type I1/2 p38α MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target … NM Walter, HK Wentsch, M Bührmann, SM Bauer, E Döring, ... Journal of medicinal chemistry 60 (19), 8027-8054, 2017 | 36 | 2017 |
Surface-crosslinked poly (3-mercaptopropyl) methylsiloxane-coatings on silica as new platform for low-bleed mass spectrometry-compatible functionalized stationary phases … A Zimmermann, J Horak, A Sievers-Engler, C Sanwald, W Lindner, ... Journal of Chromatography A 1436, 73-83, 2016 | 34 | 2016 |
Papain-functionalized gold nanoparticles as heterogeneous biocatalyst for bioanalysis and biopharmaceuticals analysis S Liu, M Höldrich, A Sievers-Engler, J Horak, M Lämmerhofer Analytica Chimica Acta 963, 33-43, 2017 | 30 | 2017 |
Gold nanoparticle-conjugated pepsin for efficient solution-like heterogeneous biocatalysis in analytical sample preparation protocols M Höldrich, A Sievers-Engler, M Lämmerhofer Analytical and bioanalytical chemistry 408 (20), 5415-5427, 2016 | 28 | 2016 |
Molecular Recognition and Visual Detection of G‐Quadruplexes by a Dicarbocyanine Dye B Karg, A Funke, A Ficht, A Sievers‐Engler, M Lämmerhofer, K Weisz Chemistry-A European Journal 21 (39), 13802-13811, 2015 | 24 | 2015 |
Surface-anchored counterions on weak chiral anion-exchangers accelerate separations and improve their compatibility for mass-spectrometry-hyphenation U Woiwode, A Sievers-Engler, A Zimmermann, W Lindner, ... Journal of Chromatography A 1503, 21-31, 2017 | 17 | 2017 |
Preparation of fluorescent labeled gentamicin as biological tracer and its characterization by liquid chromatography and high resolution mass spectrometry U Woiwode, A Sievers-Engler, M Lämmerhofer Journal of pharmaceutical and biomedical analysis 121, 307-315, 2016 | 17 | 2016 |
Selective Targeting of G‐Quadruplex Structures by a Benzothiazole‐Based Binding Motif I Buchholz, B Karg, J Dickerhoff, A Sievers‐Engler, M Lämmerhofer, ... Chemistry-A European Journal 23 (24), 5814-5823, 2017 | 13 | 2017 |
Mastering analytical challenges for the characterization of pentacyclic triterpene mono- and diesters of Calendula officinalis flowers by non-aqueous C30 HPLC … C Nicolaus, A Sievers-Engler, R Murillo, M D'Ambrosio, M Lämmerhofer, ... Journal of pharmaceutical and biomedical analysis 118, 195-205, 2016 | 13 | 2016 |
UHPLC-ESI-MS/MS Assay for Quantification of Endocannabinoids in Cerebrospinal Fluid Using Surrogate Calibrant and Surrogate Matrix Approaches E Aydin, M Cebo, J Mielnik, H Richter, R Schüle, A Sievers-Engler, ... Journal of Pharmaceutical and Biomedical Analysis, 115090, 2022 | 11 | 2022 |
Solving the retention time repeatability problem of hydrophilic interaction liquid chromatography K Serafimov, C Knappe, F Li, A Sievers-Engler, M Lämmerhofer Journal of Chromatography A, 465060, 2024 | 7 | 2024 |
UHPLC-QTOF-MS as a valuable tool for the identification of novel faradiol fatty acid diesters of Calendula officinalis flowers C Nicolaus, A Sievers-Engler, R Murillo, M Lämmerhofer, I Merfort Planta Medica 81 (16), PW_177, 2015 | 6 | 2015 |
Ligand–receptor binding increments in enantioselective liquid chromatography A Sievers-Engler, W Lindner, M Lämmerhofer Journal of Chromatography A 1363, 79-88, 2014 | 5 | 2014 |
Peptide Analysis: Zwitterionic Chiral Ion-Exchangers as Complementary Option to HILIC and to Reversed-Phase Chromatography W Lindner, P Franco, M Lämmerhofer, A Sievers-Engler, H Gross, ... | 3 | 2016 |
Automated Sample Preparation with 6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate and Iodoacetamide Derivatization Reagents for Enantioselective Liquid Chromatography Tandem … F Li, R Karongo, D Mavridou, J Horak, A Sievers-Engler, M Lämmerhofer Journal of Chromatography A, 464349, 2023 | 1 | 2023 |
Automatic sample concentrating unit A Sievers-Engler US Patent App. 17/304,344, 2021 | 1* | 2021 |