Spatial rearrangement of the Streptomyces venezuelae linear chromosome during sporogenic development MJ Szafran, T Małecki, A Strzałka, K Pawlikiewicz, J Duława, A Zarek, ... Nature communications 12 (1), 5222, 2021 | 39 | 2021 |
Topoisomerase I (TopA) is recruited to ParB complexes and is required for proper chromosome organization during Streptomyces coelicolor sporulation M Szafran, P Skut, B Ditkowski, K Ginda, G Chandra, ... Journal of Bacteriology 195 (19), 4445-4455, 2013 | 30 | 2013 |
The coordinated positive regulation of topoisomerase genes maintains topological homeostasis in Streptomyces coelicolor MJ Szafran, M Gongerowska, P Gutkowski, J Zakrzewska-Czerwińska, ... Journal of Bacteriology 198 (21), 3016-3028, 2016 | 25 | 2016 |
Compaction and control—the role of chromosome-organizing proteins in Streptomyces MJ Szafran, D Jakimowicz, MA Elliot FEMS Microbiology Reviews 44 (6), 725-739, 2020 | 24 | 2020 |
A highly processive topoisomerase I: studies at the single-molecule level MJ Szafran, T Strick, A Strzałka, J Zakrzewska-Czerwińska, D Jakimowicz Nucleic acids research 42 (12), 7935-7946, 2014 | 24 | 2014 |
C-terminal lysine repeats in Streptomyces topoisomerase I stabilize the enzyme–DNA complex and confer high enzyme processivity A Strzałka, MJ Szafran, T Strick, D Jakimowicz Nucleic acids research 45 (20), 11908-11924, 2017 | 22 | 2017 |
Transcriptional Response of Streptomyces coelicolor to Rapid Chromosome Relaxation or Long-Term Supercoiling Imbalance MJ Szafran, M Gongerowska, T Małecki, M Elliot, D Jakimowicz Frontiers in microbiology 10, 1605, 2019 | 21 | 2019 |
Amsacrine Derivatives Selectively Inhibit Mycobacterial Topoisomerase I (TopA), Impair M. smegmatis Growth and Disturb Chromosome Replication MJ Szafran, M Kołodziej, P Skut, B Medapi, A Domagała, D Trojanowski, ... Frontiers in microbiology 9, 1592, 2018 | 20 | 2018 |
Enhanced binding of an HU homologue under increased DNA supercoiling preserves chromosome organisation and sustains Streptomyces hyphal growth A Strzałka, A Kois-Ostrowska, M Kędra, T Łebkowski, G Bieniarz, ... Nucleic Acids Research 50 (21), 12202-12216, 2022 | 10 | 2022 |
Bacterial type I topoisomerases-biological function and potential use as targets for antibiotic treatments M Szafran, J Zakrzewska-Czerwińska, D Jakimowicz Postepy Higieny i Medycyny Doswiadczalnej (Online) 67, 130-142, 2013 | 10* | 2013 |
Combining transposon mutagenesis and reporter genes to identify novel regulators of the topA promoter in Streptomyces M Gongerowska-Jac, MJ Szafran, D Jakimowicz Microbial Cell Factories 20 (1), 99, 2021 | 5 | 2021 |
Global Chromosome Topology and the Two-Component Systems in Concerted Manner Regulate Transcription in Streptomyces M Gongerowska-Jac, MJ Szafran, J Mikołajczyk, J Szymczak, M Bartyńska, ... Msystems 6 (6), e01142-21, 2021 | 3 | 2021 |
A highly processive actinobacterial topoisomerase I – thoughts on Streptomyces’ demand for an enzyme with a unique C-terminal domain MJ Szafran, A Strzałka, D Jakimowicz Microbiology 166 (2), 120-128, 2020 | 3 | 2020 |
Searching for new antibiotics--inhibitors of bacterial chromosome replication D Trojanowski, P Skut, J Hołówka, MJ Szafran Postepy Higieny i Medycyny Doswiadczalnej (Online) 68, 701-714, 2014 | 3 | 2014 |
The activity of CobB1 protein deacetylase contributes to nucleoid compaction in Streptomyces venezuelae spores by increasing HupS affinity for DNA J Duława-Kobeluszczyk, A Strzałka, M Tracz, M Bartyńska, K Pawlikiewicz, ... Nucleic Acids Research 52 (12), 7112-7128, 2024 | 2 | 2024 |
Regulation of gene expression in the bacterial cell by Fur family proteins M Szafran, T Olczak POSTĘPY BIOCHEMII 52, 430, 2008 | 1 | 2008 |
SMC modulates ParB engagement in segregation complexes in Streptomyces K Pawlikiewicz, A Strzałka, M Majkowski, J Duława-Kobeluszczyk, ... bioRxiv, 2024.10. 17.618854, 2024 | | 2024 |
Significance of the CTP-binding motif for the interactions of S. coelicolor ParB with DNA, chromosome segregation and sporogenic hyphal growth. J Szymczak, A Strzalka, D Jakimowicz, MJ Szafran bioRxiv, 2024.12. 04.625172, 2024 | | 2024 |