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Marcin Szafran
Marcin Szafran
Geverifieerd e-mailadres voor uni.wroc.pl
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Spatial rearrangement of the Streptomyces venezuelae linear chromosome during sporogenic development
MJ Szafran, T Małecki, A Strzałka, K Pawlikiewicz, J Duława, A Zarek, ...
Nature communications 12 (1), 5222, 2021
392021
Topoisomerase I (TopA) is recruited to ParB complexes and is required for proper chromosome organization during Streptomyces coelicolor sporulation
M Szafran, P Skut, B Ditkowski, K Ginda, G Chandra, ...
Journal of Bacteriology 195 (19), 4445-4455, 2013
302013
The coordinated positive regulation of topoisomerase genes maintains topological homeostasis in Streptomyces coelicolor
MJ Szafran, M Gongerowska, P Gutkowski, J Zakrzewska-Czerwińska, ...
Journal of Bacteriology 198 (21), 3016-3028, 2016
252016
Compaction and control—the role of chromosome-organizing proteins in Streptomyces
MJ Szafran, D Jakimowicz, MA Elliot
FEMS Microbiology Reviews 44 (6), 725-739, 2020
242020
A highly processive topoisomerase I: studies at the single-molecule level
MJ Szafran, T Strick, A Strzałka, J Zakrzewska-Czerwińska, D Jakimowicz
Nucleic acids research 42 (12), 7935-7946, 2014
242014
C-terminal lysine repeats in Streptomyces topoisomerase I stabilize the enzyme–DNA complex and confer high enzyme processivity
A Strzałka, MJ Szafran, T Strick, D Jakimowicz
Nucleic acids research 45 (20), 11908-11924, 2017
222017
Transcriptional Response of Streptomyces coelicolor to Rapid Chromosome Relaxation or Long-Term Supercoiling Imbalance
MJ Szafran, M Gongerowska, T Małecki, M Elliot, D Jakimowicz
Frontiers in microbiology 10, 1605, 2019
212019
Amsacrine Derivatives Selectively Inhibit Mycobacterial Topoisomerase I (TopA), Impair M. smegmatis Growth and Disturb Chromosome Replication
MJ Szafran, M Kołodziej, P Skut, B Medapi, A Domagała, D Trojanowski, ...
Frontiers in microbiology 9, 1592, 2018
202018
Enhanced binding of an HU homologue under increased DNA supercoiling preserves chromosome organisation and sustains Streptomyces hyphal growth
A Strzałka, A Kois-Ostrowska, M Kędra, T Łebkowski, G Bieniarz, ...
Nucleic Acids Research 50 (21), 12202-12216, 2022
102022
Bacterial type I topoisomerases-biological function and potential use as targets for antibiotic treatments
M Szafran, J Zakrzewska-Czerwińska, D Jakimowicz
Postepy Higieny i Medycyny Doswiadczalnej (Online) 67, 130-142, 2013
10*2013
Combining transposon mutagenesis and reporter genes to identify novel regulators of the topA promoter in Streptomyces
M Gongerowska-Jac, MJ Szafran, D Jakimowicz
Microbial Cell Factories 20 (1), 99, 2021
52021
Global Chromosome Topology and the Two-Component Systems in Concerted Manner Regulate Transcription in Streptomyces
M Gongerowska-Jac, MJ Szafran, J Mikołajczyk, J Szymczak, M Bartyńska, ...
Msystems 6 (6), e01142-21, 2021
32021
A highly processive actinobacterial topoisomerase I – thoughts on Streptomyces’ demand for an enzyme with a unique C-terminal domain
MJ Szafran, A Strzałka, D Jakimowicz
Microbiology 166 (2), 120-128, 2020
32020
Searching for new antibiotics--inhibitors of bacterial chromosome replication
D Trojanowski, P Skut, J Hołówka, MJ Szafran
Postepy Higieny i Medycyny Doswiadczalnej (Online) 68, 701-714, 2014
32014
The activity of CobB1 protein deacetylase contributes to nucleoid compaction in Streptomyces venezuelae spores by increasing HupS affinity for DNA
J Duława-Kobeluszczyk, A Strzałka, M Tracz, M Bartyńska, K Pawlikiewicz, ...
Nucleic Acids Research 52 (12), 7112-7128, 2024
22024
Regulation of gene expression in the bacterial cell by Fur family proteins
M Szafran, T Olczak
POSTĘPY BIOCHEMII 52, 430, 2008
12008
SMC modulates ParB engagement in segregation complexes in Streptomyces
K Pawlikiewicz, A Strzałka, M Majkowski, J Duława-Kobeluszczyk, ...
bioRxiv, 2024.10. 17.618854, 2024
2024
Significance of the CTP-binding motif for the interactions of S. coelicolor ParB with DNA, chromosome segregation and sporogenic hyphal growth.
J Szymczak, A Strzalka, D Jakimowicz, MJ Szafran
bioRxiv, 2024.12. 04.625172, 2024
2024
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Artikelen 1–18