| Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion J Zhou, SH Tan, V Nicolas, C Bauvy, ND Yang, J Zhang, Y Xue, ... Cell research 23 (4), 508-523, 2013 | 447 | 2013 |
| Artesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma Z Li, H Dai, X Huang, J Feng, J Deng, Z Wang, X Yang, Y Liu, Y Wu, ... Acta Pharmacologica Sinica 42 (2), 301-310, 2021 | 237 | 2021 |
| Critical role of pro-apoptotic Bcl-2 family members in andrographolide-induced apoptosis in human cancer cells J Zhou, S Zhang, O Choon-Nam, HM Shen Biochemical pharmacology 72 (2), 132-144, 2006 | 226 | 2006 |
| Fatty acid activation in carcinogenesis and cancer development: Essential roles of long-chain acyl-CoA synthetases Y Tang, J Zhou, SC Hooi, YM Jiang, GD Lu Oncology letters 16 (2), 1390-1396, 2018 | 192 | 2018 |
| Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways J Zhang, S Ng, J Wang, J Zhou, SH Tan, N Yang, Q Lin, D Xia, HM Shen Autophagy 11 (4), 629-642, 2015 | 180 | 2015 |
| Induction of autophagy by palmitic acid via protein kinase C-mediated signaling pathway independent of mTOR (mammalian target of rapamycin) SH Tan, G Shui, J Zhou, JJE Li, BH Bay, MR Wenk, HM Shen Journal of Biological Chemistry 287 (18), 14364-14376, 2012 | 179 | 2012 |
| Quercetin induces p53‐independent cancer cell death through lysosome activation by the transcription factor EB and reactive oxygen species‐dependent ferroptosis ZX Wang, J Ma, XY Li, Y Wu, H Shi, Y Chen, G Lu, HM Shen, GD Lu, ... British journal of pharmacology 178 (5), 1133-1148, 2021 | 177 | 2021 |
| Artesunate induces cell death in human cancer cells via enhancing lysosomal function and lysosomal degradation of ferritin ND Yang, SH Tan, S Ng, Y Shi, J Zhou, KSW Tan, WSF Wong, HM Shen Journal of Biological Chemistry 289 (48), 33425-33441, 2014 | 177 | 2014 |
| Full-coverage regulations of autophagy by ROS: from induction to maturation J Zhou, XY Li, YJ Liu, J Feng, Y Wu, HM Shen, GD Lu Autophagy 18 (6), 1240-1255, 2022 | 155 | 2022 |
| Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53-mediated death receptor 4 up-regulation J Zhou, GD Lu, CS Ong, CN Ong, HM Shen Molecular cancer therapeutics 7 (7), 2170-2180, 2008 | 154 | 2008 |
| Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin J Zhou, CN Ong, GM Hur, HM Shen Biochemical pharmacology 79 (9), 1242-1250, 2010 | 134 | 2010 |
| Critical role of CAV1/caveolin-1 in cell stress responses in human breast cancer cells via modulation of lysosomal function and autophagy Y Shi, SH Tan, S Ng, J Zhou, ND Yang, GB Koo, KA McMahon, RG Parton, ... Autophagy 11 (5), 769-784, 2015 | 127 | 2015 |
| ACSL4 is a predictive biomarker of sorafenib sensitivity in hepatocellular carcinoma J Feng, P Lu, G Zhu, SC Hooi, Y Wu, X Huang, H Dai, P Chen, Z Li, W Su, ... Acta Pharmacologica Sinica 42 (1), 160-170, 2021 | 125 | 2021 |
| A quantitative chemical proteomics approach to profile the specific cellular targets of andrographolide, a promising anticancer agent that suppresses tumor metastasis J Wang, XF Tan, P Yang, J Zhou, M Gao, Z Li, TK Lim, Y He, CS Ong, ... Molecular & Cellular Proteomics 13 (3), 876-886, 2014 | 116 | 2014 |
| Andrographolide sensitizes cisplatin-induced apoptosis via suppression of autophagosome-lysosome fusion in human cancer cells J Zhou, SE Hu, SH Tan, R Cao, Y Chen, D Xia, X Zhu, XF Yang, CN Ong, ... Autophagy 8 (3), 338-349, 2012 | 115 | 2012 |
| Anti‐inflammatory and anti‐oxidative effects of cherries on Freund's adjuvant‐induced arthritis in rats YH He, J Zhou, YS Wang, C Xiao, Y Tong, JCO Tang, ASC Chan, AP Lu Scandinavian journal of rheumatology 35 (5), 356-358, 2006 | 111 | 2006 |
| Luteolin induces G1 arrest in human nasopharyngeal carcinoma cells via the Akt–GSK-3β–Cyclin D1 pathway CS Ong, J Zhou, CN Ong, HM Shen Cancer letters 298 (2), 167-175, 2010 | 107 | 2010 |
| (−)-Epigallocatechin-3-gallate induces non-apoptotic cell death in human cancer cells via ROS-mediated lysosomal membrane permeabilization Y Zhang, ND Yang, F Zhou, T Shen, T Duan, J Zhou, Y Shi, XQ Zhu, ... Public Library of Science 7 (10), e46749, 2012 | 99 | 2012 |
| CCAAT/enhancer binding protein α predicts poorer prognosis and prevents energy starvation–induced cell death in hepatocellular carcinoma GD Lu, YH Ang, J Zhou, J Tamilarasi, B Yan, YC Lim, S Srivastava, ... Hepatology 61 (3), 965-978, 2015 | 85 | 2015 |
| Impaired autophagy due to constitutive mTOR activation sensitizes TSC2-null cells to cell death under stress S Ng, YT Wu, B Chen, J Zhou, HM Shen Autophagy 7 (10), 1173-1186, 2011 | 75 | 2011 |